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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-08

Hannah E. Shaw

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Also affiliated: University of Maryland, Baltimore (2024); United States Department of Justice (2024); Drug Enforcement Administration (2024)

4 h-index 8 pubs 31 cited

  • Analgesics, Opioid
  • Animals
  • Fentanyl
  • Male
  • Mice
  • Narcotic Antagonists
  • Locomotion
  • Motor Activity
  • Cannabinoids
  • Naloxone
  • Respiratory Insufficiency
  • Cannabinoid Receptor Agonists
  • Furans
  • Mice, Inbred C57BL
  • Opioid-Related Disorders

Biography and Research Information

OverviewAI-generated summary

Hannah E. Shaw investigates the pharmacological effects and abuse liability of novel psychoactive substances. Her research involves animal models, primarily mice, to study drug-induced behaviors such as locomotion and respiratory depression, as well as the potential for dependence and withdrawal. Recent work has examined the effects of synthetic cannabinoid receptor agonists, arylcyclohexylamines, and fentanyl analogues, assessing their interactions with opioid systems and the efficacy of antagonists like naloxone.

Shaw's publications also explore the neurocognitive effects of various drugs, including those with phencyclidine-like properties and their implications for psychosis-like symptoms. She has investigated the interoceptive effects of lysergamides and the impact of psychedelics on opioid consumption and withdrawal. Her collaborators include William E. Fantegrossi, Brenda M. Gannon, Jeffery H. Moran, and Marina Avram, all from the University of Arkansas for Medical Sciences, with whom she has co-authored multiple publications. Shaw's work contributes to understanding drug mechanisms and potential therapeutic interventions.

Metrics

  • h-index: 4
  • Publications: 8
  • Citations: 31

Selected Publications

  • Interoceptive effects of N1-substituted lysergamides in rats: Role of agonist affinity at 5-hydroxytryptamine receptors and in vivo metabolism to lysergic acid diethylamide (2026)
    Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
  • Effects of Psychedelics Lysergic Acid Diethylamide and R (–)-2,5-Dimethoxy-4-Iodoamphetamine on Oral Opioid Consumption and Naloxone-Precipitated Withdrawal in Male C57Bl/6J Mice (2026)
    Psychedelic Medicine DOI OpenAlex
  • Effects of psychostimulants on locomotor activity in the BTBR T+ Itpr3tf/J mouse: implications for comorbid autism spectrum disorder and attention deficit hyperactivity disorder (2025)
    Psychopharmacology DOI OpenAlex
  • Effects of orally self-administered furanyl fentanyl and acryl fentanyl in mice: antinociception, dependence and withdrawal, and defense of consumption (2025)
    Neuropharmacology 5 citations DOI OpenAlex
  • Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice (2025)
    Drug and Alcohol Dependence 7 citations DOI OpenAlex
  • Phencyclidine-Like Abuse Liability and Psychosis-Like Neurocognitive Effects of Novel Arylcyclohexylamine Drugs of Abuse in Rodents (2024)
    Journal of Pharmacology and Experimental Therapeutics 7 citations DOI OpenAlex
  • Balancing Therapeutic Efficacy and Safety of MDMA and Novel MDXX Analogues as Novel Treatments for Autism Spectrum Disorder (2023)
    Psychedelic Medicine 10 citations DOI OpenAlex

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Collaboration Network

26 Collaborators 9 Institutions 2 Countries

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