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Presence Current · Arkansas
Last published 2023
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Kalee N. Holloway

Researcher

Faculty Researcher

6 h-index 7 pubs 95 cited

  • Ethanol
  • Alcoholism
  • Animals
  • Mice
  • Neuroinflammatory Diseases
  • Male
  • Cerebellum
  • Female
  • Hippocampus
  • Mice, Inbred C57BL
  • Transcriptome
  • Disease Models, Animal
  • Adaptor Proteins, Vesicular Transport
  • Adaptor Proteins, Signal Transducing
  • Toll-Like Receptor 4

Biography and Research Information

OverviewAI-generated summary

Kalee N. Holloway's research investigates the effects of ethanol consumption on neuroinflammation and molecular changes in the brain. Her work has focused on chronic plus binge mouse models of alcohol use disorder, examining specific brain regions like the cerebellum and hippocampus. Holloway's publications explore how ethanol administration influences glial gene expression and activates signaling pathways such as TLR4 and MyD88-dependent signaling. She has also studied the divergent and overlapping transcriptome responses in the hippocampus and cerebellum following developmental ethanol exposure during critical neurogenic periods, particularly in the context of fetal alcohol spectrum disorders. Holloway collaborates with researchers at the University of Arkansas for Medical Sciences, including Paul D. Drew, Cynthia J.M. Kane, James C. Douglas, and Tonya Rafferty, with whom she shares multiple publications. Her published work includes studies on neuroinflammatory diseases, alcoholism, and the molecular underpinnings of these conditions.

Metrics

  • h-index: 6
  • Publications: 7
  • Citations: 95

Selected Publications

  • Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023)
    Cells 32 citations DOI OpenAlex
  • Balancing Therapeutic Efficacy and Safety of MDMA and Novel MDXX Analogues as Novel Treatments for Autism Spectrum Disorder (2023)
    Psychedelic Medicine 10 citations DOI OpenAlex
  • Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023)
    Frontiers in Neuroscience 13 citations DOI OpenAlex
  • Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression (2023)
    Cells 10 citations DOI OpenAlex
  • Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022)
    The American Journal of Drug and Alcohol Abuse 16 citations DOI OpenAlex
  • A Case of Confluence: A Middle-Aged Woman with Progressive Dyspnea and Hypoxia (2022)
  • Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period (2021)
    Alcoholism Clinical and Experimental Research 14 citations DOI OpenAlex

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Collaboration Network

14 Collaborators 4 Institutions 1 Country

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