Kalee N. Holloway

Researcher

University of Arkansas for Medical Sciences

faculty

6 h-index 7 pubs 79 cited

Research Areas

Neuroscience and Neuropharmacology Research Immune Response and Inflammation Substance Abuse Treatment and Outcomes Birth, Development, and Health Neurological disorders and treatments Behavioral and Psychological Studies Genomics and Phylogenetic Studies

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Research Group

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OverviewAI-generated summary

Kalee N. Holloway's research investigates the neurobiological impacts of alcohol consumption, particularly focusing on chronic and binge alcohol administration models in mice. Her work examines how ethanol affects neuroinflammation, exploring the roles of specific molecular signaling pathways such as TLR4 and MyD88. Holloway's publications have analyzed transcriptomic changes in the cerebellum and hippocampus following developmental ethanol exposure, providing insights into potential mechanisms underlying fetal alcohol spectrum disorders and alcohol use disorder. She has also explored the molecular responses to ethanol in these brain regions, identifying altered glial gene expression and neuroinflammation. In addition to her work on alcohol's effects, Holloway has contributed to research on novel therapeutic treatments for autism spectrum disorder, specifically investigating MDMA and related analogues. Her scholarly output includes seven publications with a total of 79 citations and an h-index of 6. She has collaborated extensively with researchers at the University of Arkansas for Medical Sciences, including Paul D. Drew, Cynthia J.M. Kane, James C. Douglas, and Tonya Rafferty.

Metrics

h-index: 6
Publications: 7
Citations: 79

Selected Publications

Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023) DOI
Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023) DOI
Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression (2023) DOI
Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022) DOI
A Case of Confluence: A Middle-Aged Woman with Progressive Dyspnea and Hypoxia (2022) DOI
Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period (2021) DOI