Biography and Research Information
OverviewAI-generated summary
J S James researches the effects of synthetic cannabinoid receptor agonists on fentanyl-induced respiratory depression. In a 2025 publication, James and collaborators investigated how these agonists can worsen respiratory depression caused by fentanyl and potentially make naloxone, an overdose reversal medication, less effective in mice. A 2024 publication explored a similar mechanism, suggesting a potential reason for "Narcan-resistant" overdoses. James's work contributes to understanding complex drug interactions and their implications for overdose treatment. This research is conducted in collaboration with other researchers at the University of Arkansas for Medical Sciences, including William E. Fantegrossi, Brenda M. Gannon, Hannah Shaw, and Jeffery H. Moran, as evidenced by shared publications.
Metrics
- h-index: 2
- Publications: 4
- Citations: 10
Selected Publications
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Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice (2025)
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Respiratory Depressant Effects of Fentanyl in Combination With Synthetic Cannabinoid Receptor Agonists: A Potential Mechanism for “Narcan-Resistant” Overdose (2024)
Collaboration Network
Top Collaborators
William E. Fantegrossi
University of Arkansas for Medical Sciences
2 shared publications
In database
- Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
- Respiratory Depressant Effects of Fentanyl in Combination With Synthetic Cannabinoid Receptor Agonists: A Potential Mechanism for “Narcan-Resistant” Overdose
Hannah Shaw
University of Arkansas for Medical Sciences
1 shared publication
In database
- Respiratory Depressant Effects of Fentanyl in Combination With Synthetic Cannabinoid Receptor Agonists: A Potential Mechanism for “Narcan-Resistant” Overdose
Brenda M. Gannon
University of Arkansas for Medical Sciences
1 shared publication
In database
- Respiratory Depressant Effects of Fentanyl in Combination With Synthetic Cannabinoid Receptor Agonists: A Potential Mechanism for “Narcan-Resistant” Overdose
Jessica Thrush
University of Arkansas for Medical Sciences
1 shared publication
In database
- Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
Taher M Yusufali
University of Arkansas for Medical Sciences
1 shared publication
In database
- Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
Hannah E. Shaw
University of Arkansas for Medical Sciences
1 shared publication
In database
- Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
Marina Avram
Arkansas Department of Agriculture
1 shared publication
In database
- Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
Jeffery H. Moran
Arkansas Department of Agriculture
1 shared publication
In database
- Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice
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