Thomas S. Risch
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Also affiliated: Rutgers, The State University of New Jersey (2026); Frostburg State University (2006); University of Georgia (1997); Max Planck Institute for Molecular Genetics (2018); Arkansas Biosciences Institute (2020–2023); Auburn University (1995–2006)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Thomas S. Risch's research program investigates the molecular underpinnings of various human cancers, with a significant focus on medulloblastoma and colorectal cancer. His work has explored the whole-genome landscape of medulloblastoma subtypes, identifying enhancer hijacking as a mechanism that activates oncogenes and revealing subgroup-specific cellular origins through active enhancers. In colorectal cancer, his research has involved molecular dissection of pre-clinical models to identify biomarkers that predict sensitivity to EGFR inhibitors.
Risch has also contributed to understanding the genetic drivers of epigenetic and transcriptional variation in human immune cells. His broader research interests extend to the molecular evolution of early-onset prostate cancer, where he has worked to identify molecular risk markers and clinical trajectories. Additionally, his work includes the genomics and drug profiling of acute lymphoblastic leukemia, identifying recurrent mutation patterns and potential therapeutic options. He has also been involved in curating clinically annotated data for the ovarian cancer transcriptome.
His scholarship metrics include an h-index of 30, with 108 total publications and over 6,300 citations. Risch has collaborated with researchers at Arkansas State University, including Virginie Rolland, Stacy J. Scherman, and Valerie M. Kearny, as well as Renn Tumlison from Henderson State University.
Metrics
- h-index: 21
- Publications: 73
- Citations: 1,568
Positions
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Medical Genetics Center 2023–presentBioinformatics ORCID
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Research assistent 2016–2020Max Planck Institute for Molecular Genetics OWL - Yaspo lab / Research Group Gene Regulation & System Biology of Cancer ORCID
Selected Publications
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Winter roost selection of two bottomland forest bat specialists, southeastern myotis and Rafinesque’s big-eared bats (2026)
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Spring Migration Behavior of Female Indiana Bats Overwintering in Arkansas (2023)
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Microhabitat of Myotis leibii summer roosts at the southwestern periphery of their range (2023)
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Drivers of Southern Flying Squirrel (Glaucomys volans) Aggregation Size in South Carolina, U.S.A. (2022)
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Fall and winter activity of two bat species in response to winter flooding and decreasing temperature (2022)
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Broad scale functional connectivity for Asian elephants in the Nepal-India transboundary region (2022)
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Distribution and Roost Site Selection of Eastern Small-Footed Bats (Myotis leibii) in Mountains of West-Central Arkansas (2022)
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Biomarker Metabolites Discriminate between Physiological States of Field, Cave and White-nose Syndrome Diseased Bats (2022)
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Changes in habitat suitability over a two decade period before and after Asian elephant recolonization (2020)
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Disease recovery in bats affected by white-nose syndrome (2020)
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Assessment of the Portable C-320 Electronic Nose for Discrimination of Nine Insectivorous Bat Species: Implications for Monitoring White-Nose Syndrome (2020)
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Morphological Discrimination of Gray Bats and Southeastern Bats (2019)
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Implications of forest management practices for sex-specific habitat use by Nycticeius humeralis (2019)
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Habitat use by Asian elephants: Context matters (2019)
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Bat Occupancy Estimates and Species Richness at Cache River National Wildlife Refuge (2017)
Collaboration Network
Top Collaborators
- Isolation and Identification of an Extracellular Subtilisin-Like Serine Protease Secreted by the Bat Pathogen Pseudogymnoascus destructans
- Disease recovery in bats affected by white-nose syndrome
- Sebaceous Lipid Profiling of Bat Integumentary Tissues: Quantitative Analysis of Free Fatty Acids, Monoacylglycerides, Squalene, and Sterols
- Fatty Acid Methyl Ester Profiles of Bat Wing Surface Lipids
- Profiling the Triacylglyceride Contents in Bat Integumentary Lipids by Preparative Thin Layer Chromatography and MALDI-TOF Mass Spectrometry
Showing 5 of 10 shared publications
- Sex-specific foraging habits and roost characteristics ofNycticeius humeralisin north-central Arkansas
- Habitat use of female gray bats assessed using aerial telemetry
- Abundance and Distribution of Overwintering Red-tailed Hawks and American Kestrels in an Agricultural Landscape in Northeastern Arkansas
- Implications of forest management practices for sex-specific habitat use by Nycticeius humeralis
- Distribution and Roost Site Selection of Eastern Small-Footed Bats (Myotis leibii) in Mountains of West-Central Arkansas
Showing 5 of 9 shared publications
- Reproductive and resource benefits to large female body size in a mammal with female-biased sexual size dimorphism
- The Use of Nest Boxes to Sample Arboreal Vertebrates
- Keeping Tabs: Are Redundant Marking Systems Needed for Rodents?
- The burden of motherhood: gliding locomotion in mammals influences maternal reproductive investment
- Characterization of microsatellite DNA loci for the southern flying squirrel (Glaucomys volans)
Showing 5 of 7 shared publications
- Isolation and Identification of an Extracellular Subtilisin-Like Serine Protease Secreted by the Bat Pathogen Pseudogymnoascus destructans
- Sebaceous Lipid Profiling of Bat Integumentary Tissues: Quantitative Analysis of Free Fatty Acids, Monoacylglycerides, Squalene, and Sterols
- Fatty Acid Methyl Ester Profiles of Bat Wing Surface Lipids
- Profiling the Triacylglyceride Contents in Bat Integumentary Lipids by Preparative Thin Layer Chromatography and MALDI-TOF Mass Spectrometry
- Triacylglyceride composition and fatty acyl saturation profile of a psychrophilic and psychrotolerant fungal species grown at different temperatures
Showing 5 of 7 shared publications
- Distribution and Habitat Attributes of an Endemic Subspecies of Pocket Gopher
- New Records of the Eastern Small-footed Bat (Myotis leibii) in Arkansas
- Morphological Discrimination of Gray Bats and Southeastern Bats
- Spring Migration Behavior of Female Indiana Bats Overwintering in Arkansas
- New Records and Notes on the Ecology of the Northern Long-Eared Bat (Myotis septentrionalis) in Arkansas
- Selection of tree roosts by male Indiana bats during the autumn swarm in the Ozark Highlands, USA
- Distribution and Roost Site Selection of Eastern Small-Footed Bats (Myotis leibii) in Mountains of West-Central Arkansas
- Morphological Discrimination of Gray Bats and Southeastern Bats
- New Records and Notes on the Ecology of the Northern Long-Eared Bat (Myotis septentrionalis) in Arkansas
- Microhabitat of Myotis leibii summer roosts at the southwestern periphery of their range
- How do land‐use practices affect human—elephant conflict in nepal?
- Willingness to pay for mitigating human-elephant conflict by residents of Nepal
- Habitat use by Asian elephants: Context matters
- Changes in habitat suitability over a two decade period before and after Asian elephant recolonization
- Broad scale functional connectivity for Asian elephants in the Nepal-India transboundary region
- Sebaceous Lipid Profiling of Bat Integumentary Tissues: Quantitative Analysis of Free Fatty Acids, Monoacylglycerides, Squalene, and Sterols
- Fatty Acid Methyl Ester Profiles of Bat Wing Surface Lipids
- Triacylglyceride composition and fatty acyl saturation profile of a psychrophilic and psychrotolerant fungal species grown at different temperatures
- Glycerophospholipid Analysis of Eastern Red Bat (Lasiurus Borealis) Hair by Electrospray Ionization Tandem Mass Spectrometry
- Fatty Acid Methyl Ester Profiles of Bat Wing Surface Lipids
- Habitat use of female gray bats assessed using aerial telemetry
- Captures of the Tome's sword-nosed bat, _Lonchorhina aurita_ (Chiroptera, Phyllostomidae), from Ometepe Island, Nicaragua, and range implications for this species
- Spring Migration Behavior of Female Indiana Bats Overwintering in Arkansas
- Distribution and Habitat Attributes of an Endemic Subspecies of Pocket Gopher
- Amphibian, Reptile, and Small Mammal Associates of Ozark Pocket Gopher Habitat in Izard County, Arkansas
- Responses of Bats to Forest Fragmentation in the Mississippi River Alluvial Valley, Arkansas, USA
- Drivers of Southern Flying Squirrel (Glaucomys volans) Aggregation Size in South Carolina, U.S.A.
- How do land‐use practices affect human—elephant conflict in nepal?
- Willingness to pay for mitigating human-elephant conflict by residents of Nepal
- Habitat use by Asian elephants: Context matters
- Changes in habitat suitability over a two decade period before and after Asian elephant recolonization
- Assessment of the Portable C-320 Electronic Nose for Discrimination of Nine Insectivorous Bat Species: Implications for Monitoring White-Nose Syndrome
- Implications of forest management practices for sex-specific habitat use by Nycticeius humeralis
- Biomarker Metabolites Discriminate between Physiological States of Field, Cave and White-nose Syndrome Diseased Bats
- Drivers of Southern Flying Squirrel (Glaucomys volans) Aggregation Size in South Carolina, U.S.A.
- Selection of tree roosts by male Indiana bats during the autumn swarm in the Ozark Highlands, USA
- Distribution of Bats in Bottomland Hardwood Forests of the Arkansas Delta Region
- Indiana Bat (Myotis sodalis) Maternity Colonies in Arkansas
- The separate effects of egg size and parental quality on the development of ornamental plumage coloration
- Seasonal Tradeoffs in Reproductive Investment in a Multi-Brooded Passerine
- First Observation of Cavity Nesting by a Female Blue Grosbeak
- Disease recovery in bats affected by white-nose syndrome
- Sebaceous Lipid Profiling of Bat Integumentary Tissues: Quantitative Analysis of Free Fatty Acids, Monoacylglycerides, Squalene, and Sterols
- Fatty Acid Methyl Ester Profiles of Bat Wing Surface Lipids
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