Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
David N. Church's research focuses on the molecular mechanisms underlying cancer, particularly endometrial and colorectal cancers. His work investigates the role of specific gene mutations, such as those in the POLE proofreading domain, and their impact on cancer prognosis and the identification of potential therapeutic targets. He has published extensively on the clinicopathological and molecular characterization of various cancer types, including the interpretation of somatic mutations in endometrial carcinoma and the practical guidance for mismatch repair-deficiency testing.
His scholarship includes a significant publication record, with a total of 242 publications and over 9,400 citations, contributing to his h-index of 45. Church collaborates with researchers at the University of Arkansas for Medical Sciences, including Arny A. Ferrando and Robert R. Wolfe, as well as Shiloah A. Kviatkovsky at the University of Arkansas at Fayetteville, indicating a network of shared research interests and projects. He leads a research group and maintains an active lab website, suggesting ongoing research activities and mentorship.
Metrics
- h-index: 45
- Publications: 242
- Citations: 9,411
Positions
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Assistant ProfessorUniversity of Arkansas for Medical Sciences Institutional directory
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University of OxfordWellcome Trust Centre for Human Genetics; Department of Oncology ORCID
Selected Publications
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Guidelines for replacement of a balloon gastrostomy tube in infants and pediatric patients: The American Society for Parenteral and Enteral Nutrition (2026)
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From Anecdote to Evidence: Dispelling Myths in Bodybuilding and Physique Sports (2026)
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Guidelines for nutrition in adults with head and neck cancer: The American Society for Parenteral and Enteral Nutrition (2026)
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Elevated miR-194-5p Expression during Short-Term Energy Deficit Attenuates Postexercise Muscle Protein Synthesis by Inhibiting Anabolic Signaling (2026)
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Effects of acute essential amino acid intake on post-prandial raw bioimpedance and fluid shifts between healthy young and older adults: An exploratory pilot study (2025)
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The effect of bed rest, unilateral limb immobilization and head‐down tilt on muscle protein synthesis: A systematic review and meta‐analysis (2025)
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Exploring the multifactorial causes and therapeutic strategies for anabolic resistance in sarcopenia: A systems modeling study (2025)
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The Effects of Essential Amino Acid Supplementation on Hippocampal Neurotrophin, Dopaminergic and Serotonergic Changes in an Overtraining Mouse Model (2025)
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Antiaging agents: pharmacological therapy targeted at preserving skeletal muscle size and function in aging adults (2025)
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Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond (2025)
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Effects of exercise with or without a hypocaloric diet on intermuscular and intramuscular fat: a systematic review (2025)
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Muscle Protein Synthesis Response to Whole-Foods and Free-Form Essential Amino Acids: An Exploratory Analysis (2025)
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The effect of nandrolone decanoate administration on fatigue during a volume‐overload stress in male mice (2025)
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The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta‐Analysis (2025)
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Proximate analysis and concordance with nutritional labeling of most sold protein bars in Santiago, Chile (2025)
Grants & Funding
As listed on this researcher's institutional profile.
- Effects of lean pork loin intake and GLP-1 receptors agonist on protein homeostasis and glucose regulation in prediabetic adults National Pork Board
- Ferrando - Optimizing Performance for Soldiers II (OPS II ) Pennington/USARIEM U.S. Army Research Institute of Environmental Medicine via Pennington Biomedical Research Center
- ABI C. OBrien NIH COBRE FY26 Y4 State of Arkansas
- INVESTIGATING THE ROLE OF SERUM RESPONSE FACTOR IN CARDIAC MITOCHONDRIAL BIOENERGETICS AND FUNCTION IN THE AGING HEART National Pork Board
- Effects of lean pork on protein homeostasis and glucose regulation in prediabetic adults. National Pork Board
Collaboration Network
Top Collaborators
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- The contributory role of vascular health in age‐related anabolic resistance
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
Showing 5 of 37 shared publications
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
- Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults
Showing 5 of 27 shared publications
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- Mitigation of Muscle Loss in Stressed Physiology: Military Relevance
- Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
Showing 5 of 13 shared publications
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- Comparison of basal whole‐body protein kinetics and muscle protein synthesis between young and older adults
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Continuous oral stable isotope ingestion to measure whole-body protein turnover
Showing 5 of 9 shared publications
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit
- Mitigation of Muscle Loss in Stressed Physiology: Military Relevance
- Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
Showing 5 of 8 shared publications
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
- Comparison of basal whole‐body protein kinetics and muscle protein synthesis between young and older adults
- The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism
Showing 5 of 7 shared publications
- Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
Showing 5 of 7 shared publications
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations
- Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study
- Effects of exercise with or without a hypocaloric diet on intermuscular and intramuscular fat: a systematic review
Showing 5 of 7 shared publications
- Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding
- Metabolic Evaluation of the Dietary Guidelines’ Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial
- Comparison of basal whole‐body protein kinetics and muscle protein synthesis between young and older adults
- The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism
- Whole-body protein kinetic models to quantify the anabolic response to dietary protein consumption
Showing 5 of 6 shared publications
- Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Acute hypoxia reduces exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Acute hypoxia reduces exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Acute hypoxia reduces exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
- Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations
- Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study
- Testosterone Administration Does Not Affect The Muscle Metabolome During Severe Energy Deficit And Subsequent Recovery
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
- Consideration of the role of protein quality in determining dietary protein recommendations
- The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism
- Whole-body protein kinetic models to quantify the anabolic response to dietary protein consumption
- Muscle Protein Synthesis Response to Whole-Foods and Free-Form Essential Amino Acids: An Exploratory Analysis
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
- 440 Muscle Protein Synthesis and Whole-Body Protein Balance Following Ingestion of Beef or a Soy Protein Based Meat Alternative
- Exploratory Analysis Of Protein Metabolism Sex Difference Following Feeding
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