Li Xia

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NCTR

Also affiliated: Chongqing University of Posts and Telecommunications (2011); Dalian Ocean University (2007–2008); Jiangnan University (2024); University of North Carolina at Chapel Hill (2002); Nanjing Agricultural University (2014); United States Food and Drug Administration (2025); Central South University (2007–2011); University of Electronic Science and Technology of China (2022–2023); Harbin Medical University (2011); Shanghai Jiao Tong University (2021–2023); Yunnan Agricultural University (2007); Wuhan University of Technology (2021); Chinese Academy of Sciences (2023); Tianjin Foreign Studies University (2012); Qufu Normal University (2011); Purdue University West Lafayette (2024); Fudan University (2003–2022); WuXi AppTec (China) (2024); Tianjin Medical University Cancer Institute and Hospital (2016); Hefei Institutes of Physical Science (2023); Southwest Medical University (2023); China University of Geosciences (2011); Sichuan Agricultural University (2008); Anshan Normal University (2007–2011); Affiliated Hospital of Southwest Medical University (2023); Jiangsu Academy of Agricultural Sciences (2014); Mianyang Central Hospital (2022); Burke Medical Research Institute (2005–2010); Sichuan Cancer Hospital (2023); Wuxi No.2 People's Hospital (2024); Chinese Academy of Forestry (2020); Research Institute of Forestry (2020); Heze University (2020); Peking University Third Hospital (2024); Children's Hospital of Fudan University (2019–2021); First Hospital of Xi'an (2014); Guangdong Baiyun University (2012); University of Chinese Academy of Sciences (2007); UNC Lineberger Comprehensive Cancer Center (2002); State Key Laboratory of Tree Genetics and Breeding (2020); Laiwu Vocational and Technical College (2009); Tianjin Medical University (2016); Chongqing Jiaotong University (2018); Nanjing Medical University (2012); Xinjiang University of Finance and Economics (2007–2012)

16 h-index 104 pubs 5,755 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Li Xia's research focuses on the molecular mechanisms underlying cellular processes, particularly the role of epigenetic modifications in gene regulation and disease. Xia has investigated histone methylation, including the purification and functional characterization of histone methyltransferases like SET8 and ESET. This work explores how these enzymes interact with transcription factors and influence gene expression codes. Further research has examined the impact of histone modifications, such as lysine 27 methylation, on gene silencing via Polycomb-group proteins. Xia's recent publications also delve into the interplay between metabolic processes, like glycolysis, and epigenetic modifications, such as histone lactylation, in driving oncogenesis. Additionally, Xia has explored the role of long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) in modulating immune responses, specifically M2 macrophage activation and inflammation, in conditions like asthma, atopic dermatitis, and psoriasis.

Metrics

h-index: 16
Publications: 104
Citations: 5,755

Selected Publications

N-nitroso-ethylisopropylamine mutagenicity in rat liver using the cII transgenic mutation assay and duplex sequencing analysis of genomic DNA (2025)

Chemico-Biological Interactions 2 citations DOI OpenAlex
Germline mutagenicity of molnupiravir and its active form, β-d-N4-hydroxycytidine, in Caenorhabditis elegans evaluated using whole-genome sequencing (2025)

Toxicology Letters 2 citations DOI OpenAlex
Genotoxicity of nanoparticles evaluated using the in vitro micronucleus assay, a review of recent data § (2025)

Journal of Environmental Science and Health Part C 2 citations DOI OpenAlex