Biography and Research Information
OverviewAI-generated summary
Arundhati Chavan's research focuses on the molecular mechanisms underlying acute megakaryoblastic leukemia (AMKL) and acute myeloid leukemia (AML). Her work investigates how genetic fusions, such as CBFA2T3-GLIS2, drive transcriptional rewiring through epigenetic modifications, specifically enhancer methylation. Chavan's publications explore the role of enzymes like DNMT3B in controlling chromatin states and cell cycle networks in AML, identifying potential vulnerabilities for therapeutic intervention. She has co-authored publications with researchers at the University of Arkansas for Medical Sciences, including Samrat Roy Choudhury and Giselle Almeida Gonzalez. Chavan's research is characterized by an h-index of 1 and 5 total publications.
Metrics
- h-index: 1
- Publications: 5
- Citations: 2
Selected Publications
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Abstract 3496: Epigenetic repurposing by CBFA2T3-GLIS2 reveals a druggable DNA methylation axis in high-risk pediatric AML vulnerability in pediatric AML (2026)
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Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML (2026)
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Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia (2025)
Collaboration Network
Top Collaborators
Samrat Roy Choudhury
Arkansas Children's Hospital
3 shared publications
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
- DNMT3B Controls Enhancer-Linked Chromatin and Cell Cycle Networks in Acute Myeloid Leukemia
Pritam Biswas
Arkansas Children's Hospital
2 shared publications
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- DNMT3B Controls Enhancer-Linked Chromatin and Cell Cycle Networks in Acute Myeloid Leukemia
Giselle Almeida Gonzalez
University of Arkansas for Medical Sciences
2 shared publications
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Jason E. Farrar
Arkansas Children's Hospital
2 shared publications
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Akhilesh Kaushal
Arkansas Children's Hospital
1 shared publication
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Cory C. Padilla
Biota Pharmaceuticals (United States) (US)
1 shared publication
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Jay F. Sarthy
1 shared publication
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Soheil Meshinchi
Fred Hutch Cancer Center (US)
1 shared publication
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Rhonda E. Ries
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
1 shared publication
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Soheil Meshinchi
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
1 shared publication
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Kimberly Stephens
University of Arkansas for Medical Sciences
1 shared publication
In database
- DNMT3B Controls Enhancer-Linked Chromatin and Cell Cycle Networks in Acute Myeloid Leukemia
Similar Researchers
Based on overlapping research topics
Giselle Almeida Gonzalez
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Epigenetics and DNA Methylation
Genomics and Chromatin Dynamics
Jason E. Farrar
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Genomics and Chromatin Dynamics
Child and Adolescent Health
Akhilesh Kaushal
University of Arkansas for Medical Sciences
Epigenetics and DNA Methylation
Genomics and Chromatin Dynamics
Child and Adolescent Health
Samrat Roy Choudhury
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Epigenetics and DNA Methylation
Genomics and Chromatin Dynamics
Troy Davidson
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Child and Adolescent Health
Acute Myeloid Leukemia Research
Fraley, Patrick
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Epigenetics and DNA Methylation
Genomics and Chromatin Dynamics