Thomas Kieber‐Emmons
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Also affiliated: The Wistar Institute (1992–2008); Roswell Park Comprehensive Cancer Center (1981–2009); Centre National de la Recherche Scientifique (2003); New York State Department of Health (1986–1988); Children's Hospital of Philadelphia (1996–1998); Inserm (2003); Tel Aviv University (1998); Hebrew University of Jerusalem (1986); Korea University (1998); National Foundation for Cancer Research (1983); University of Arkansas Medical Center (2003–2019); Hospital of the University of Pennsylvania (1996); Sheba Medical Center (1998); Centre de Recherche des Cordeliers (2003); Central Arkansas Veterans Healthcare System (2004); Philadelphia VA Medical Center (1995–2001); University of Pennsylvania Health System (1997); Korea University (1998); University of Pennsylvania (1988–2014); KU Leuven (2003)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Thomas Kieber‐Emmons' research focuses on harnessing antibody polyspecificity for cancer immunotherapy and understanding immune responses to vaccines. His work includes designing bioactive peptides based on antibody structures and investigating antibody reactivity against tumor-associated antigens. Kieber‐Emmons has also published on the P10s-PADRE vaccine's effects in breast cancer patients and discusses topics related to vaccine risk communication and expert panel discussions on antigenic sin.
Metrics
- h-index: 42
- Publications: 243
- Citations: 5,624
Selected Publications
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When Reassurance Falls Short: Rethinking Vaccine Risk Communication (2025)
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Abstract PO5-02-05: Assessing Vaccine-Mediated Cellular Immune Responses in Patients Receiving Combined Vaccine and Chemotherapy Treatment (2024)
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Abstract 3860: Characterizing peripheral immune correlates of tumor response in breast cancer patients immunized with the P10s-PADRE vaccine (2024)
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Abstract 700: Induction of cancer-specific T-cell responses in patients immunized with P10s-PADRE vaccine (2023)
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Thoughts on mRNA Vaccine Response (2023)
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VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen (2023)
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Harnessing Antibody Polyspecificity for Cancer Immunotherapy (2022)
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Living with Endemic COVID-19 (2022)
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Abstract P2-14-15: Timing of the immunization defines immune signature of a peptide cancer vaccine combined with Neoadjuvant chemotherapy in HR+ breast cancer patients (2022)
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Cancer Patients and COVID-19 Vaccination (2021)
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P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses (2021)
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Expert Panel Discussion on Antigenic Sin (2021)
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Antibodies are the Forefront of Today's Medicine (2021)
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Antibodies in the Thick of Things (2021)
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“Why Not Hybridomas” (2021)
Collaboration Network
Top Collaborators
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Tumor-Associated Glycans and Immune Surveillance
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
Showing 5 of 48 shared publications
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
Showing 5 of 30 shared publications
- Tumor-Associated Glycans and Immune Surveillance
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- The Promise of Anti-idiotype Revisited
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Multiple Antigenic Mimotopes of HIV Carbohydrate Antigens
Showing 5 of 26 shared publications
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
- CHST11 gene expression and DNA methylation in breast cancer
- Moving a Carbohydrate Mimetic Peptide into the clinic
Showing 5 of 20 shared publications
- Relevance of Pathological Complete Response after Neoadjuvant Therapy for Breast Cancer
- Breast Cancer Immunotherapy: An Update
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Moving a Carbohydrate Mimetic Peptide into the clinic
- Harnessing benefit from targeting tumor associated carbohydrate antigens
Showing 5 of 19 shared publications
- Relevance of Pathological Complete Response after Neoadjuvant Therapy for Breast Cancer
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
- Moving a Carbohydrate Mimetic Peptide into the clinic
Showing 5 of 10 shared publications
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- A Mimic of Tumor Rejection Antigen-Associated Carbohydrates Mediates an Antitumor Cellular Response
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
Showing 5 of 8 shared publications
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Carbohydrate-Mimetic Peptides for Pan Anti-Tumor Responses
- Defining the Recognition Elements of Lewis Y-Reactive Antibodies
- The Potential Role of Solvation in Antibody Recognition of the Lewis Y Antigen
- Structure-Based Peptide Mimicry of Tumor-Associated Antigens
Showing 5 of 8 shared publications
- Relevance of Pathological Complete Response after Neoadjuvant Therapy for Breast Cancer
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Moving a Carbohydrate Mimetic Peptide into the clinic
- Harnessing benefit from targeting tumor associated carbohydrate antigens
- Defining and Managing Expectations for Early Immunotherapy Cancer Trials
Showing 5 of 8 shared publications
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
- Immunomodulatory Effects of Radiofrequency Ablation in a Breast Cancer Model
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
Showing 5 of 7 shared publications
- Obesity promotes 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in female zucker rats
- CHST11 gene expression and DNA methylation in breast cancer
- Obesity increases the incidence of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in an ovariectomized Zucker rat model
- Expression analysis of carbohydrate antigens in ductal carcinoma in situof the breast by lectin histochemistry
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
Showing 5 of 7 shared publications
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
- CHST11 gene expression and DNA methylation in breast cancer
- Carbohydrate (Chondroitin 4) Sulfotransferase-11-Mediated Induction of Epithelial-Mesenchymal Transition and Generation of Cancer Stem Cells
- Abstract 4018: DNA methylation controls CHST11 gene expression in breast cancer
Showing 5 of 6 shared publications
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
- Characterization of the glycosylation profile of the human breast cancer cell line, MDA-231, and a bone colonizing variant
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
- P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract P2-14-15: Timing of the immunization defines immune signature of a peptide cancer vaccine combined with Neoadjuvant chemotherapy in HR+ breast cancer patients
- Carbohydrate-Mimetic Peptides for Pan Anti-Tumor Responses
- Defining the Recognition Elements of Lewis Y-Reactive Antibodies
- The Potential Role of Solvation in Antibody Recognition of the Lewis Y Antigen
- Carbohydrate Mimetic Peptide Vaccines
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