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Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
F
Fariba Jousheghany
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Also affiliated: University of Arkansas Medical Center (2005–2014); University of Pennsylvania (2003)
14 h-index
42 pubs
707 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Fariba Jousheghany's research focuses on the molecular mechanisms of breast cancer metastasis, particularly the role of chondroitin sulfates. Her work has investigated how these glycosaminoglycans, specifically CSPG4 and CHST11 gene expression, contribute to the formation of surface P-selectin ligands on aggressive breast cancer cells, facilitating metastasis. Jousheghany has also explored the potential of targeting tumor-associated carbohydrate antigens through vaccine development. This includes preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma, and a Phase I clinical trial of such a vaccine in stage IV breast cancer patients. Her research network includes collaborators such as Behjatolah Monzavi‐Karbassi and Thomas Kieber‐Emmons at the University of Arkansas for Medical Sciences, with whom she has co-authored multiple publications. Jousheghany's scholarship metrics include an h-index of 14, with 42 publications and 707 citations.
Metrics
- h-index: 14
- Publications: 42
- Citations: 707
Selected Publications
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Abstract 2908: SR-A antagonism remodels the myeloid population of tumor immune microenvironment, expands CD8-positive T cells, and enhances antitumor efficacy in vivo (2026)
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Class A scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer (2026)
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Abstract PO5-02-05: Assessing Vaccine-Mediated Cellular Immune Responses in Patients Receiving Combined Vaccine and Chemotherapy Treatment (2024)
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Abstract 3860: Characterizing peripheral immune correlates of tumor response in breast cancer patients immunized with the P10s-PADRE vaccine (2024)
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Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A (2024)
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Abstract 700: Induction of cancer-specific T-cell responses in patients immunized with P10s-PADRE vaccine (2023)
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VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen (2023)
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Abstract P2-14-15: Timing of the immunization defines immune signature of a peptide cancer vaccine combined with Neoadjuvant chemotherapy in HR+ breast cancer patients (2022)
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P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses (2021)
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Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study (2020)
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Carbohydrate (Chondroitin 4) Sulfotransferase-11-Mediated Induction of Epithelial-Mesenchymal Transition and Generation of Cancer Stem Cells (2020)
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Macrophage Class A Scavenger Receptors Bind Tumor‐Associated Carbohydrate Antigens and Promote Breast Cancer Growth and Metastases in Mice (2020)
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Abstract P3-09-18: Immunization of breast cancer patients in combination with standard-of-care chemotherapy: Results of a phase Ib clinical trial (2020)
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Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells—in vitro and ex vivo study (2020)
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Carbamate Derivatives of Colchicine Show Potent Activity toward Primary Acute Lymphoblastic Leukemia and Primary Breast Cancer Cells: <i>In Vitro</i> and <i>Ex Vivo</i> Study (2019)
Collaboration Network
Top Collaborators
Thomas Kieber‐Emmons
University of Arkansas for Medical Sciences
32 shared publications
In database
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
Showing 5 of 32 shared publications
Behjatolah Monzavi‐Karbassi
University of Arkansas for Medical Sciences
32 shared publications
In database
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
Showing 5 of 32 shared publications
Eric R. Siegel
University of Arkansas for Medical Sciences
18 shared publications
In database
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
- CHST11 gene expression and DNA methylation in breast cancer
- Moving a Carbohydrate Mimetic Peptide into the clinic
Showing 5 of 18 shared publications
Issam Makhoul
Arkansas Cardiology
10 shared publications
In database
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Moving a Carbohydrate Mimetic Peptide into the clinic
- P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract P6-10-06: Inducing immune responses to tumor associated carbohydrate antigens by a carbohydrate mimetic peptide vaccine: Clinical experience in phase I and phase II trials
Showing 5 of 10 shared publications
Cécile Artaud
University of Arkansas for Medical Sciences (US)
9 shared publications
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- A Mimic of Tumor Rejection Antigen-Associated Carbohydrates Mediates an Antitumor Cellular Response
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
Showing 5 of 9 shared publications
Laura F. Hutchins
Winthrop Rockefeller Foundation
7 shared publications
In database
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Pre-diagnosis blood glucose and prognosis in women with breast cancer
- Moving a Carbohydrate Mimetic Peptide into the clinic
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
Showing 5 of 7 shared publications
Leah Hennings
Winthrop Rockefeller Foundation (US)
6 shared publications
- Chondroitin sulfate glycosaminoglycans as major P‐selectin ligands on metastatic breast cancer cell lines
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
- Carbohydrate Mimetic Peptides Augment Carbohydrate-Reactive Immune Responses in the Absence of Immune Pathology
Showing 5 of 6 shared publications
Anastas Pashov
Bulgarian Academy of Sciences (BG)
5 shared publications
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Preclinical studies of carbohydrate mimetic peptide vaccines for breast cancer and melanoma
- Carbohydrate Mimetic Peptides Augment Carbohydrate-Reactive Immune Responses in the Absence of Immune Pathology
- Fucosylated lactosamines participate in adhesion of HIV-1 envelope glycoprotein to dendritic cells
- Evaluating strategies to enhance the anti-tumor immune response to a carbohydrate mimetic peptide vaccine
Aiwei Yao‐Borengasser
University of Arkansas for Medical Sciences
5 shared publications
In database
- Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in aggressive breast cancer cells
- CHST11 gene expression and DNA methylation in breast cancer
- Carbohydrate (Chondroitin 4) Sulfotransferase-11-Mediated Induction of Epithelial-Mesenchymal Transition and Generation of Cancer Stem Cells
- Abstract 4018: DNA methylation controls CHST11 gene expression in breast cancer
- Abstract 2704: Ectopic expression of CHST11 promotes proliferation and migration of human breast cancer cells.
Thomas J. Kelly
University of Arkansas for Medical Sciences
5 shared publications
In database
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
- VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen
- Macrophage Class A Scavenger Receptors Bind Tumor‐Associated Carbohydrate Antigens and Promote Breast Cancer Growth and Metastases in Mice
- Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A
- Abstract 2908: SR-A antagonism remodels the myeloid population of tumor immune microenvironment, expands CD8-positive T cells, and enhances antitumor efficacy in vivo
Steven R. Post
University of Arkansas for Medical Sciences
5 shared publications
In database
- VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen
- Macrophage Class A Scavenger Receptors Bind Tumor‐Associated Carbohydrate Antigens and Promote Breast Cancer Growth and Metastases in Mice
- Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A
- Class A scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer
- Abstract 2908: SR-A antagonism remodels the myeloid population of tumor immune microenvironment, expands CD8-positive T cells, and enhances antitumor efficacy in vivo
Soheila Korourian
University of Arkansas for Medical Sciences
4 shared publications
In database
- CHST11 gene expression and DNA methylation in breast cancer
- Reduction of Spontaneous Metastases through Induction of Carbohydrate Cross-Reactive Apoptotic Antibodies
- Deficiency in surface expression of E‐selectin ligand promotes lung colonization in a mouse model of breast cancer
- Reduction of tumor growth and spontaneous metastasis through induction of carbohydrate cross-reactive apoptotic antibodies
Angela Pennisi
University of Arkansas for Medical Sciences (US)
4 shared publications
- Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
- Moving a Carbohydrate Mimetic Peptide into the clinic
- Abstract P6-10-06: Inducing immune responses to tumor associated carbohydrate antigens by a carbohydrate mimetic peptide vaccine: Clinical experience in phase I and phase II trials
- Abstract P3-09-18: Immunization of breast cancer patients in combination with standard-of-care chemotherapy: Results of a phase Ib clinical trial
Bernice Nounamo
University of Arkansas for Medical Sciences
4 shared publications
In database
- VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen
- Abstract 700: Induction of cancer-specific T-cell responses in patients immunized with P10s-PADRE vaccine
- Abstract 3860: Characterizing peripheral immune correlates of tumor response in breast cancer patients immunized with the P10s-PADRE vaccine
- Abstract PO5-02-05: Assessing Vaccine-Mediated Cellular Immune Responses in Patients Receiving Combined Vaccine and Chemotherapy Treatment
Behjatolah Monzavi Karbassi
University of Arkansas for Medical Sciences
3 shared publications
In database
- Reduction of tumor growth and spontaneous metastasis through induction of carbohydrate cross-reactive apoptotic antibodies
- Evaluating the immunogenicity of carbohydrate mimotopes and synthetic conjugates
- Abstract 2908: SR-A antagonism remodels the myeloid population of tumor immune microenvironment, expands CD8-positive T cells, and enhances antitumor efficacy in vivo
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