Behjatolah Monzavi‐Karbassi

Federal Grant PI High Impact

Associate Professor

UAMS

Also affiliated: Russian Academy of Sciences (1998); University of Arkansas Medical Center (2020); Kurchatov Institute (1998); Cancer Research Center (2006); Winthrop Rockefeller Foundation (2008–2023); Institute of Molecular Genetics (1998); Arkansas Department of Agriculture (2014); University of Pennsylvania (1999–2003)

Faculty Researcher

24 h-index 78 pubs 1,619 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Behjatolah Monzavi‐Karbassi's research focuses on cancer immunology and treatment, particularly in the context of breast cancer. His work investigates the induction of immune responses to tumor-associated antigens, as demonstrated by studies on the P10s-PADRE vaccine combined with chemotherapy in breast cancer patients. These investigations aim to assess both humoral and cellular immune responses and characterize peripheral immune correlates of tumor response.

Further research explores the role of the tumor microenvironment and its interaction with the immune system. This includes examining tumor exosome-macrophage interactions and the involvement of tumor-associated glycans. Monzavi‐Karbassi also studies potential therapeutic targets, such as scavenger receptor A (SR-A) in breast cancer, and investigates antibodies targeting specific molecules like chondroitin sulfate proteoglycan 4 (CSPG4) for their reactivity against tumor antigens. His research extends to animal models, including studies on how soy protein concentrate intake affects inflammatory markers in rats.

Monzavi‐Karbassi has a scholarly record of 78 publications, with 1,615 citations, and an h-index of 24. He has received federal funding from the NIH/National Cancer Institute for his work on SR-A as a therapeutic target in breast cancer. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Fariba Jousheghany, Bernice Nounamo, Steven R. Post, and Reza Hakkak.

Metrics

h-index: 24
Publications: 78
Citations: 1,619

Selected Publications

Abstract PO5-02-05: Assessing Vaccine-Mediated Cellular Immune Responses in Patients Receiving Combined Vaccine and Chemotherapy Treatment (2024)

Cancer Research DOI OpenAlex
Abstract 3860: Characterizing peripheral immune correlates of tumor response in breast cancer patients immunized with the P10s-PADRE vaccine (2024)

Cancer Research DOI OpenAlex
Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A (2024)

Cancer Research DOI OpenAlex
The Tumor Microenvironment and Immune Response in Breast Cancer (2024)

International Journal of Molecular Sciences 2 citations DOI OpenAlex
Abstract 700: Induction of cancer-specific T-cell responses in patients immunized with P10s-PADRE vaccine (2023)

Cancer Research DOI OpenAlex
Feeding Soy Protein Concentrates with Low and High Isoflavones Alters 9 and 18 Weeks Serum Isoflavones and Inflammatory Protein Levels in Lean and Obese Zucker Rats (2023)

Journal of Medicinal Food 9 citations DOI OpenAlex
VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen (2023)

International Journal of Molecular Sciences 3 citations DOI OpenAlex
Feeding Obese Zucker Rats With Soy Protein Concentrate With High Isoflavones Compared to Low Isoflavones Leads to a Significant Reduction of Serum Tumor Necrosis Factor-α (2022)

Current Developments in Nutrition DOI OpenAlex
Abstract P2-14-15: Timing of the immunization defines immune signature of a peptide cancer vaccine combined with Neoadjuvant chemotherapy in HR+ breast cancer patients (2022)

Cancer Research DOI OpenAlex
P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses (2021)

Oncotarget 11 citations DOI OpenAlex
Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study (2020)

Frontiers in Oncology 2 citations DOI OpenAlex
Carbohydrate (Chondroitin 4) Sulfotransferase-11-Mediated Induction of Epithelial-Mesenchymal Transition and Generation of Cancer Stem Cells (2020)

Pharmacology 10 citations DOI OpenAlex
Macrophage Class A Scavenger Receptors Bind Tumor‐Associated Carbohydrate Antigens and Promote Breast Cancer Growth and Metastases in Mice (2020)

The FASEB Journal DOI OpenAlex
Abstract P3-09-18: Immunization of breast cancer patients in combination with standard-of-care chemotherapy: Results of a phase Ib clinical trial (2020)

Cancer Research DOI OpenAlex
Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells—in vitro and ex vivo study (2020)

Journal of Biochemical and Molecular Toxicology 16 citations DOI OpenAlex