Brandon S.B. Canup Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

National Center for Toxicological Research

faculty

13 h-index 27 pubs 1,199 cited

Research Areas

Nanoparticle-Based Drug Delivery Cancer Treatment and Pharmacology Phytochemicals and Antioxidant Activities Immune Response and Inflammation Pharmacological Effects and Toxicity Studies Gut microbiota and health Extracellular vesicles in disease

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OverviewAI-generated summary

Brandon S.B. Canup's research investigates the application of nanotherapeutics for disease prevention and treatment. His work has focused on utilizing natural nanovesicles derived from sources like tea flowers and leaves for targeted delivery. Publications include studies on how these nanovesicles can suppress metastatic breast cancer through mechanisms like reactive oxygen species (ROS) generation and microbiota modulation. Other research areas involve tumor microenvironment-responsive nanococktails for synergistic cancer treatment and the development of quadruple-responsive nanoparticles for combination chemotherapy in metastatic breast cancer. Canup has also explored the intracellular release of drugs via external stimuli, such as UV irradiation of photosensitive nanoparticles, and has investigated sex-based differences in the immunotoxicity of silver nanoparticles. His scholarship metrics include an h-index of 13, 27 total publications, and 1,199 total citations.