HongDuck Yun
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Researcher
Graduate Student Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
HongDuck Yun's research focuses on understanding and suppressing hepatocellular carcinoma (HCC), a significant form of liver cancer. Their work investigates the dual targeting of epigenetic regulators EZH2 and LSD1 to disrupt signaling pathways crucial for HCC cell survival and proliferation. Specifically, Yun's recent publications highlight how this dual approach can overcome resistance mechanisms and immune evasion in HCC by interfering with the Sonic Hedgehog signaling pathway. This pathway involves key proteins like EZH2 and GLI1, and its disruption is a central theme in Yun's investigations. The research also examines the broader implications of epigenetic modifications, including the role of histone demethylases, in cancer development.
Metrics
- Publications: 2
Selected Publications
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Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling (2026)
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Abstract 1276: Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma. (2026)
Collaboration Network
Top Collaborators
- Abstract 1276: Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma.
- Abstract 1276: Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma.
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
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