Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
HongDuck Yun's research focuses on the molecular mechanisms underlying hepatocellular carcinoma (HCC), particularly investigating therapeutic strategies that target epigenetic regulators. His recent work has explored the dual targeting of EZH2 and LSD1, epigenetic enzymes, to suppress HCC progression. This approach aims to disrupt signaling pathways, such as the Sonic Hedgehog pathway, which are implicated in liver cancer development and resistance to existing treatments. Yun's publications also touch upon overcoming immune evasion in HCC through these combined epigenetic and kinase-targeting strategies. His scholarly output, though limited in quantity, indicates a focus on disease mechanisms research within oncology, specifically concerning gene expression regulation and cancer cell signaling.
Metrics
- h-index: 1
- Publications: 2
- Citations: 1
Selected Publications
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Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling (2026)
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Abstract 1276: Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma. (2026)
Collaboration Network
Top Collaborators
- Abstract 1276: Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma.
- Abstract 1276: Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma.
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
- Dual Targeting of EZH2 and LSD1 Suppresses Hepatocellular Carcinoma via Disruption of Sonic Hedgehog Signaling
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