Marjan Boerma Institution Verified

Sourced from institutional research profiles (UAMS TRI or ARA).

High Impact

Professor

University of Arkansas for Medical Sciences

faculty

37 h-index 212 pubs 5,057 cited

Research Areas

Cancer Treatment and Pharmacology Radiation Therapy and Dosimetry Cardiovascular Function and Risk Factors Pharmacological Effects and Toxicity Studies Immune Response and Inflammation Molecular Biology Techniques and Applications Extracellular vesicles in disease

Links

ORCID Lab Website Research Group UAMS TRI Profile

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OverviewAI-generated summary

Marjan Boerma's research investigates the biological mechanisms underlying cardiovascular injury caused by cancer therapies, such as chemotherapy and radiation. Her work aims to identify potential countermeasures for intervention. Using pre-clinical research models, Boerma's group assesses cardiac function, tissue structure, and molecular alterations in response to various cancer treatments, both alone and in combination.

Her research group has explored the role of specific molecular pathways in radiation-induced heart disease, including the involvement of TLR4. Additionally, her team has investigated methods for isolating extracellular vesicles for molecular phenotyping, with potential applications in detecting biomarkers for radiation exposure. Boerma's scholarly contributions include 212 publications, an h-index of 37, and over 5,000 citations, designating her as a highly cited researcher.

Boerma collaborates with several researchers at the University of Arkansas for Medical Sciences, including Vijayalakshmi Sridharan, Igor Koturbash, Ashley Nemec-Bakk, and Rupak Pathak, with whom she has co-authored multiple publications. She leads an active research group and maintains a laboratory website.

Metrics

h-index: 37
Publications: 212
Citations: 5,057

Selected Publications

Adverse Outcome Pathways Applied to Space Radiation Research (2025) DOI
Sex-specific immune alterations in mice following long-term simulated microgravity and chronic irradiation (2025) DOI
A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity (2025) DOI
Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming (2025) DOI
Distinct Urinary Metabolite Signatures Mirror In Vivo Oxidative Stress-Related Radiation Responses in Mice (2024) DOI
Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading (2024) DOI
<scp>AOP</scp> report: Development of an adverse outcome pathway for deposition of energy leading to abnormal vascular remodeling (2024) DOI
Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease (2024) DOI
Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury (2024) DOI
Effects of confounding and effect-modifying lifestyle, environmental and medical factors on risk of radiation-associated cardiovascular disease (2024) DOI
Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma (2024) DOI
A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment (2024) DOI
A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment (2023) DOI
PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular aging (2023) DOI
Development of an adverse outcome pathway for deposition of energy leading to vascular remodeling (2023) DOI