Match tier
Institution-verified
Presence
Current · Arkansas
Last published
2026
Sources
Institutional record
Refreshed
2026-08-20
M
Marjan Boerma
Sourced from institutional research profiles (UAMS TRI or ARA).
Federal Grant PI
High Impact
Professor
Also affiliated: American Heart Association (2006); National Institutes of Health (2007); United States Department of Veterans Affairs (2007); Loma Linda University (2015); University of Arkansas Medical Center (2010–2022); Leiden University Medical Center (2002–2005); Moffitt Cancer Center (2012); scPharmaceuticals (United States) (2015); Central Arkansas Veterans Healthcare System (2006–2015); Las Vegas Institute (2008); Winthrop Rockefeller Foundation (2021–2025); Arkansas Biosciences Institute (2006); Creative Research Enterprises (United States) (2015); Charité - Universitätsmedizin Berlin (2012)
Faculty Researcher
37 h-index
223 pubs
5,274 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Marjan Boerma's research focuses on understanding the biological mechanisms underlying cardiovascular injury caused by cancer therapies, including radiation and chemotherapy. Utilizing pre-clinical research models, Boerma investigates the cardiac side effects of these treatments, both individually and in combination. The research assesses cardiac function, tissue structure, and molecular alterations in response to radiation and chemotherapy.
Boerma has secured significant federal funding for this work, including a $1,471,447 grant from the NIH/National Institute of General Medical Sciences for the Center for Studies of Host Response to Cancer Therapy, and another $1,147,500 grant for COBRE Phase III from the same agency. Additional funding includes $395,650 from the NIH/NIH Office of the Director for the Development of a minimally invasive biomarker assay to detect delayed radiation injury, and $588,106 from the NIH/NIH Office of the Director for research on The Protein C Pathway in Mitigation of Radiation-Induced Endothelial and Vascular Dysfunction.
Boerma's scholarly contributions are reflected in a high-impact researcher designation, with an h-index of 37, over 5,000 citations, and 221 publications. Key collaborators at the University of Arkansas for Medical Sciences include Vijayalakshmi Sridharan, Igor Koturbash, Ashley Nemec-Bakk, and Rupak Pathak.
Metrics
- h-index: 37
- Publications: 223
- Citations: 5,274
Selected Publications
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Dataset for: Multi-organ acute and delayed effects following exposure to neutron radiation (2026)
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Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025)
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Adverse Outcome Pathways Applied to Space Radiation Research (2025)
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Sex-specific immune alterations in mice following long-term simulated microgravity and chronic irradiation (2025)
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A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity (2025)
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Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming (2025)
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Bridging Earth and Space: A Flexible and Resilient Federated Learning Framework Deployed on the International Space Station (2025)
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Distinct Urinary Metabolite Signatures Mirror In Vivo Oxidative Stress-Related Radiation Responses in Mice (2024)
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Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading (2024)
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<scp>AOP</scp> report: Development of an adverse outcome pathway for deposition of energy leading to abnormal vascular remodeling (2024)
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Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease (2024)
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Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury (2024)
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Effects of confounding and effect-modifying lifestyle, environmental and medical factors on risk of radiation-associated cardiovascular disease (2024)
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Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma (2024)
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Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma (2024)
Federal Grants 4 $3,602,703 total
NIH
Contact PI
Aug 2025 - May 2030
NIH
Contact PI
Feb 2020 - Jan 2026
Development of a minimally invasive biomarker assay to detect delayed radiation injury
NIH
Contact PI
Jun 2017 - Nov 2022
The Protein C Pathway in Mitigation of Radiation-Induced Endothelial and Vascular Dysfunction
NIH
Contact PI
Jun 2015 - May 2026
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- ABI C. OBrien NIH COBRE FY26 Y4 State of Arkansas
- Effects of Chronic and Single-dose Charged Particle Exposure on Cardiac Function and Structure in Multiple Animal Models National Aeronautics & Space Administration
- Platelets in radiation-induced immune dysregulation NIH/Nat. Inst. of Allergy & Infectious Diseases
- Impact of hemodynamics on efferocytosis in endothelial cells NIH/Nat. Heart, Lung & Blood Institute
- Metabolomics Based Prediction of Delayed Effects of Acute Radiation Exposure NIH/Nat. Inst. of Allergy & Infectious Diseases via Nelson Scientific Labs, LLC
- Tocotrienol as a countermeasure against high-energy charged particle-induced carcinogenesis, cardiovascular disease, and central nervous system effects- Resubmission National Aeronautics & Space Administration
- Advanced development of multi-omics based assays to predict late radiation organinjuries - the DEARE-Watch project NIH
- Team Leader for the Radiation Effects Team National Space Biomedical Research Institute via Baylor College of Medicine
- Role of TLR4 in Radiation-induced Cardiomyopathy/Upstate NY US Department of Defense via SUNY Upstate Medical University
- Phosphodiesterase inhibitors and tocols in radiation-induced heart disease American Cancer Society, Inc.
- Role of Senescent Cells in Radiation-induced Pulmonary Fibrosis NIH
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences
- COBRE Phase III _ Boerma NIH/Nat. Inst. of General Medical Sciences
- Center for Molecular Interactions in Cancer (CMIC) NIH
- Integration of in-silico and in-vivo Models for Determining Preclinical Indicators and/or Integrated Biomarkers of Radiation-Induced Vascular Dysfunction National Aeronautics & Space Administration via Louisiana State University
- Photobiomodulation to Ameliorate Neuronal Degeneration and Cognitive Decline after Mixed Field Irradiation - Continuation National Aeronautics & Space Administration
- Radiation-Induced Heart Disease: Mechanisms and Interventions NIH
- Oral Interleukin 11 as a Countermeasure against Radiation Injury to Gut NIH
- Center for Research on Cardiac and Vascular Effects of Space Radiation National Space Biomedical Research Institute
- MRNA translational Control of Cell Cycle Progression American Cancer Society, Inc.
Collaboration Network
Top Collaborators
Vijayalakshmi Sridharan
University of Arkansas for Medical Sciences
16 shared publications
In database
- TLR4—A Pertinent Player in Radiation-Induced Heart Disease?
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- The M2 Gene Is a Determinant of Reovirus-Induced Myocarditis
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
Showing 5 of 16 shared publications
Yaoxiang Li
Georgetown University (US)
9 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
- Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity
Showing 5 of 9 shared publications
Amrita K. Cheema
Georgetown University (US)
9 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
- Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity
Showing 5 of 9 shared publications
Igor Koturbash
University of Arkansas for Medical Sciences
8 shared publications
In database
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading
- A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment
Showing 5 of 8 shared publications
Shivani Bansal
Georgetown University (US)
8 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
- Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
Showing 5 of 8 shared publications
José A. Fernández
Scripps Research Institute (US)
7 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
Showing 5 of 7 shared publications
John H. Griffin
Scripps Research Institute (US)
7 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
Showing 5 of 7 shared publications
Reid D. Landes
University of Arkansas for Medical Sciences
6 shared publications
In database
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
Showing 5 of 6 shared publications
Ashley Nemec-Bakk
University of Arkansas for Medical Sciences
6 shared publications
In database
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading
Showing 5 of 6 shared publications
Meth Jayatilake
Georgetown University (US)
6 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Distinct Urinary Metabolite Signatures Mirror In Vivo Oxidative Stress-Related Radiation Responses in Mice
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
Showing 5 of 6 shared publications
Sunil Bansal
Georgetown University (US)
6 shared publications
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
- An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
Showing 5 of 6 shared publications
Paari Dominic
Louisiana State University Health Sciences Center Shreveport (US)
5 shared publications
- Cancer Radiation Therapy May Be Associated With Atrial Fibrillation
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Abstract P098: Effects Of Occupational Radiation Exposure On The Prevalence Of Hypertension And Its Complications
- Abstract 9708: Direct Normal Irradiance from Solar Radiation Negatively Correlates With Af Hospitalization in the United States
Maohua Cao
5 shared publications
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Late Health Effects of Partial Body Irradiation Injury in a Minipig Model Are Associated with Changes in Systemic and Cardiac IGF-1 Signaling
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
Kimberly J. Krager
University of Arkansas for Medical Sciences
5 shared publications
In database
- TLR4—A Pertinent Player in Radiation-Induced Heart Disease?
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Small animal models of localized heart irradiation
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models
Jacqueline P. Williams
University of Rochester Medical Center (US)
5 shared publications
- A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment
- All for one, though not one for all: team players in normal tissue radiobiology
- Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading
- A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment
- Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming
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