Colin D. Kay
Professor
faculty
COM | Peds Developmental Nutrition
Research Areas
Biography and Research Information
OverviewAI-generated summary
Colin D. Kay, Professor in the Department of Pediatrics at the University of Arkansas for Medical Sciences, investigates the effects of dietary compounds on cardiometabolic health. His research group focuses on understanding how specific bioactive components, such as anthocyanins found in fruits like blueberries and strawberries, can modulate physiological responses to dietary challenges. Recent studies led by Kay have utilized randomized controlled trials to examine the impact of these compounds on metabolic and inflammatory markers in individuals with conditions such as metabolic syndrome and hypercholesterolemia.
Kay's work also extends to exploring novel delivery methods for bioactive compounds. This includes research on protein-polyphenol aggregate particles and spray-dried or freeze-dried protein-spinach particles, aiming to enhance the bioaccessibility of beneficial nutrients like carotenoids, chlorophylls, and phenolics. His research network includes collaborations with colleagues at the University of Arkansas for Medical Sciences, such as Mário G. Ferruzzi, with whom he has co-authored multiple publications. Kay's scholarship metrics include an h-index of 44, with over 8,700 citations across 152 publications, designating him as a highly cited researcher.
Metrics
- h-index: 45
- Publications: 149
- Citations: 8,864
Selected Publications
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Prenatal Polyphenol Intake During Late Pregnancy Is Positively Associated With Academic and IQ Scores in School-Age Children (2025)
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Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery (2025)
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Comparison of the capillary and venous blood plasma lipidomes: validation of self-collected blood for plasma lipidomics (2025)
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Identification and functional characterization of BAHD acyltransferases associated with anthocyanin acylation in blueberry (2025)
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Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial (2025)
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Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods (2024)
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Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery (2024)
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Genotype and ripening method affect carotenoid content and bio-accessibility in banana (2024)
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Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome – results from a six-month, double-blind, randomized controlled trial (2024)
Collaboration Network
Top Collaborators
- Foaming and sensory characteristics of protein-polyphenol particles in a food matrix
- Spray-dried and freeze-dried protein-spinach particles; effect of drying technique and protein type on the bioaccessibility of carotenoids, chlorophylls, and phenolics
- Boosting the Bioaccessibility of Dietary Bioactives by Delivery as Protein–Polyphenol Aggregate Particles
- High-density linkage map construction and identification of loci regulating fruit quality traits in blueberry
- The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice
Showing 5 of 20 shared publications
- An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder
- The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice
- Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro
- Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study
- Identification and functional characterization of BAHD acyltransferases associated with anthocyanin acylation in blueberry
Showing 5 of 11 shared publications
- Foaming and sensory characteristics of protein-polyphenol particles in a food matrix
- Spray-dried and freeze-dried protein-spinach particles; effect of drying technique and protein type on the bioaccessibility of carotenoids, chlorophylls, and phenolics
- Boosting the Bioaccessibility of Dietary Bioactives by Delivery as Protein–Polyphenol Aggregate Particles
- High-density linkage map construction and identification of loci regulating fruit quality traits in blueberry
- Influence of simulated food and oral processing on carotenoid and chlorophyll <i>in vitro</i> bioaccessibility among six spinach genotypes
Showing 5 of 10 shared publications
- Foaming and sensory characteristics of protein-polyphenol particles in a food matrix
- Spray-dried and freeze-dried protein-spinach particles; effect of drying technique and protein type on the bioaccessibility of carotenoids, chlorophylls, and phenolics
- Boosting the Bioaccessibility of Dietary Bioactives by Delivery as Protein–Polyphenol Aggregate Particles
- High-density linkage map construction and identification of loci regulating fruit quality traits in blueberry
- Genotype and ripening method affect carotenoid content and bio-accessibility in banana
Showing 5 of 8 shared publications
- The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice
- Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study
- Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study
- Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study
- Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro β-Cell Functions Critical for Metabolic Health
Showing 5 of 7 shared publications
- The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice
- Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study
- Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study
- Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study
- Evaluation of Poorly-Bioavailable Cocoa Flavanols and Their Gut Microbial Metabolites in Potentiating Anti-diabetic Activities Through BTBR.Cg-Lepob/ob/WiscJ Mice
Showing 5 of 6 shared publications
- The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice
- Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study
- Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study
- Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study
- Evaluation of Poorly-Bioavailable Cocoa Flavanols and Their Gut Microbial Metabolites in Potentiating Anti-diabetic Activities Through BTBR.Cg-Lepob/ob/WiscJ Mice
Showing 5 of 6 shared publications
- Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: Results from a double blind, randomized controlled trial in metabolic syndrome participants
- Strawberry Consumption, Cardiometabolic Risk Factors, and Vascular Function: A Randomized Controlled Trial in Adults with Moderate Hypercholesterolemia
- Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome – results from a six-month, double-blind, randomized controlled trial
- Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial
- PTFS11-05-23 Effect of Cultivar and Processing on the Bioavailability of (Poly)phenols Using Blueberries as a Model Fruit
- Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: Results from a double blind, randomized controlled trial in metabolic syndrome participants
- A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study
- Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome – results from a six-month, double-blind, randomized controlled trial
- Extended recommendations on the nomenclature for microbial catabolites of dietary (poly)phenols, with a focus on isomers
- Effect of age and sex on the urinary elimination of a single dose of mixed flavonoids: results from a single-arm intervention in healthy United Kingdom adults
- Gut microbes modulate the effects of the flavonoid quercetin on atherosclerosis
- Gut microbiota and diet matrix modulate the effects of the flavonoid quercetin on atherosclerosis
- The Metabolome of Food Knowledge Database: Development of a Nutrition Database to Support Precision Nutrition
- Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial
- PTFS11-05-23 Effect of Cultivar and Processing on the Bioavailability of (Poly)phenols Using Blueberries as a Model Fruit
- Performance of Urinary Phenyl-γ-Valerolactones as Biomarkers of Dietary Flavan-3-ol Exposure
- Extended recommendations on the nomenclature for microbial catabolites of dietary (poly)phenols, with a focus on isomers
- Performance of urinary phenyl-γ-valerolactones as biomarkers of dietary flavan-3-ol exposure
- OR13-07-23 Enhanced Anthocyanin Metabolite Excretion in Adults With the Genotype for Persistent Lactase Expression
- Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods
- Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery
- Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery
- Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery
- Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro
- Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial
- PTFS11-05-23 Effect of Cultivar and Processing on the Bioavailability of (Poly)phenols Using Blueberries as a Model Fruit
- Strawberry Consumption, Cardiometabolic Risk Factors, and Vascular Function: A Randomized Controlled Trial in Adults with Moderate Hypercholesterolemia
- Extended recommendations on the nomenclature for microbial catabolites of dietary (poly)phenols, with a focus on isomers
- The berry health tool chest – an evidence map and interactive resource
- Spray-dried and freeze-dried protein-spinach particles; effect of drying technique and protein type on the bioaccessibility of carotenoids, chlorophylls, and phenolics
- Influence of simulated food and oral processing on carotenoid and chlorophyll <i>in vitro</i> bioaccessibility among six spinach genotypes
- Genotype and ripening method affect carotenoid content and bio-accessibility in banana
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