Sree V. Chintapalli
Assistant Professor (non-tenure)
Also affiliated: University of Essex (2007–2013); Arkansas Children's Hospital (2016–2026); Pennsylvania State University (2011–2015); Royal College of Surgeons in Ireland (2024); University of Arkansas Medical Center (2016–2026); St. Vincent's University Hospital (2024); University of Kansas Medical Center (2025); Arkansas Children's Nutrition Center (2015–2026); Arkansas Department of Agriculture (2016–2026); University of California, Davis (2012–2014)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Sree V. Chintapalli's research focuses on the interplay between diet, the gut microbiome, and host physiology, with a particular emphasis on metabolic health and vascular complications. Chintapalli has investigated the impact of maternal obesity and diet on the developing gut microbiome in offspring, as well as the influence of specific dietary components, such as blueberries and strawberries, on vascular health in mouse models of metabolic syndrome. This work has explored mechanisms involving nitric oxide production and oxidative stress, alongside the modulation of gut microbial communities.
Further research has examined sex differences in skeletal muscle characteristics and explored the role of specific molecules, like hippuric acid, in bone metabolism, mediated by gut microbiota. Chintapalli has also contributed to a broader understanding of myoglobin's diverse functions, including its potential roles in metabolic tissues like brown adipose tissue. With 98 publications and an h-index of 25, Chintapalli is recognized as a highly cited researcher. Key collaborators include Sean H. Adams, Umesh D. Wankhade, Brian D. Piccolo, and Aline Andres, all from the University of Arkansas for Medical Sciences.
Metrics
- h-index: 26
- Publications: 97
- Citations: 1,930
Selected Publications
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Mutation-induced heme pocket destabilization in myoglobinopathy (2026)
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MyD88 signaling in trophoblasts contributes to maternal high fat diet-associated alterations in placental gene expression and lipid profiles (2026)
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Mutation induced heme pocket destabilization in myoglobinopathy (2026)
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Mutation induced heme pocket destabilization in myoglobinopathy (2026)
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Integrating fingerprint prediction and physicochemical property filtering to annotate unknown metabolites from high-resolution MS/MS spectra (2026)
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Urinary sodium excretion is associated with increased body mass index: A cross-sectional analytical study among adults in Kuala Lumpur, Malaysia (2026)
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Enhancing Mitochondrial Function in Skeletal Muscle Cells through Metabolite Modulation: Therapeutic Implications for Muscle Metabolic Diseases (2025)
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Abstract 1547 Innovative Insights into Myoglobin-Metabolite Interactions and Muscle Cell Bioenergetics (2025)
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The Effect of Mhealth Interventions on Quality of Life in HIV Patients: A GRADE Assessed Systematic Review and Meta-Analysis (2025)
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Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery (2025)
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Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice (2024)
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Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods (2024)
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Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery (2024)
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Effects of Statin and Annatto-extracted Tocotrienol Supplementation on Glucose Homeostasis, Bone Microstructure, and Gut Microbiota Composition in Obese Mice (2024)
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Effect of lactate supplementation to skeletal muscle cells on fiber type transition and cellular bioenergetics (2024)
Collaboration Network
Top Collaborators
- A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin
- Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
- Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor
- Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics
- Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy
Showing 5 of 13 shared publications
- Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
- Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics
- Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy
- Computational insights on molecular interactions of acifran with GPR109A and GPR109B
- Computational Analysis Reveals Unique Binding Patterns of Oxygenated and Deoxygenated Myoglobin to the Outer Mitochondrial Membrane
Showing 5 of 12 shared publications
- Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
- A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
Showing 5 of 11 shared publications
- A versatile delivery vehicle for cellular oxygen and fuels or metabolic sensor? A review and perspective on the functions of myoglobin
- Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
- Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor
- Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics
- Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy
Showing 5 of 11 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
- Spinal cord injury-induced neurogenic bowel: A role for host-microbiome interactions in bowel pain and dysfunction
- Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice
Showing 5 of 9 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- C‐section increases cecal abundance of the archetypal bile acid and glucocorticoid modifying <i>Lachnoclostridium [clostridium] scindens</i> in mice
- Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery
- Integrating fingerprint prediction and physicochemical property filtering to annotate unknown metabolites from high-resolution MS/MS spectra
- GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Gut Microbes Are Associated with the Vascular Beneficial Effects of Dietary Strawberry on Metabolic Syndrome‐Induced Vascular Inflammation
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice
- MyD88 signaling in trophoblasts contributes to maternal high fat diet-associated alterations in placental gene expression and lipid profiles
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice
- Metabolic and fecal microbial changes in adult fetal growth restricted mice
- Spinal cord injury-induced neurogenic bowel: A role for host-microbiome interactions in bowel pain and dysfunction
- Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods
- Spinal Cord Injury-Induced Neurogenic Bowel: A Role for Host-Microbiome Interactions in Bowel Pain and Dysfunction
- Quantitative Metabolomics-Driven Protein Target Prediction: A Computational Workflow for Precision Nutrition Discovery
- Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
- Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
- Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
- Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
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