Ellen van der Plas
Associate Professor
faculty
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Biography and Research Information
OverviewAI-generated summary
Ellen van der Plas is an Associate Professor at the University of Arkansas for Medical Sciences. Her research focuses on neurological and cognitive outcomes in various patient populations, including childhood cancer survivors, individuals with myotonic dystrophy type 1, and children with Huntington's disease. She investigates the relationship between biological markers, brain structure, and cognitive function.
Dr. van der Plas has published research examining cognitive impairment in survivors of pediatric acute lymphoblastic leukemia treated with chemotherapy, as well as the correlation between brain imaging findings and cognitive deficits in this group. Her work also explores the role of neurofilament light-chain protein as a potential biomarker for neurological conditions, including Huntington's disease and chronic kidney disease. She has led studies on the core brain symptoms of adult-onset myotonic dystrophy type 1, including cognitive deficits, apathy, and hypersomnolence, and has utilized quantitative muscle MRI to assess early muscle pathology in this condition. Her research extends to age-related cognitive changes in carriers of the mutant huntingtin gene, investigating the influence of CAG repeat length.
With an h-index of 23 and over 1,670 citations across 92 publications, Dr. van der Plas leads a research group and has collaborated with researchers such as Timothy R. Koscik, Trenesha L. Hill, Shelley E. Crary, and Joana M. Mack.
Metrics
- h-index: 23
- Publications: 92
- Citations: 1,701
Selected Publications
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A supervised STreNgth & Outpatient Exercise Regimen in pediatric patients with Acute Lymphoblastic Leukemia (STRONGER ALL) (2026)
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Association Between Sensorineural Hearing Loss and Neurocognitive Performance in Survivors of Childhood Cancer: A Systematic Review and Meta‐Analysis (2025)
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Diabetes mellitus and neurocognition: A report from the Childhood Cancer Survivor Study (2025)
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Parental Adverse Childhood Experiences and Health Care Use Among Children With Sickle Cell Disease (2025)
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An Activation Likelihood Estimation Meta-Analysis of Voxel-Based Morphometry Studies of Chemotherapy-Related Brain Volume Changes in Breast Cancer (2025)
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A Double-Blind, Randomized, Sham-Controlled Clinical Trial of Cerebellar Intermittent Theta Burst Stimulation for Bipolar Disorder: Safety, Tolerability, Mood and Cognitive Effects (2025)
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130 A supervised strength and outpatient exercise regimen in pediatric patients with acute lymphoblastic leukemia (STRONGER ALL) (2025)
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Age-Related Changes in Brain Structure in Pediatric Chronic Kidney Disease (2025)
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A double-blind, randomized, sham-controlled clinical trial of cerebellar intermittent theta burst stimulation for bipolar disorder: Safety, tolerability, mood and cognitive effects (2024)
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Characterization of brain development with neuroimaging in a female mouse model of chemotherapy treatment of acute lymphoblastic leukemia (2024)
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Risk factors for neurocognitive impairment, emotional distress, and poor quality of life in survivors of pediatric rhabdomyosarcoma: A report from the Childhood Cancer Survivor Study (2024)
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Understanding the impact of pediatric kidney transplantation on cognition: A review of the literature (2023)
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Longitudinal changes in white matter as measured with diffusion tensor imaging in adult-onset myotonic dystrophy type 1 (2023)
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Neurocognitive deficits may not resolve following pediatric kidney transplantation (2023)
Collaboration Network
Top Collaborators
- Associations between neurofilament light-chain protein, brain structure, and chronic kidney disease
- Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1
- Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children
- Quantitative muscle MRI as a sensitive marker of early muscle pathology in myotonic dystrophy type 1
- <scp>Age‐Related</scp> Cognitive Changes as a Function of <scp>CAG</scp> Repeat in Child and Adolescent Carriers of Mutant Huntingtin
Showing 5 of 20 shared publications
- Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1
- Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
- Global and Regional White Matter Fractional Anisotropy in Children with Chronic Kidney Disease
- Clinical and neuroradiological correlates of sleep in myotonic dystrophy type 1
- Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1
Showing 5 of 13 shared publications
- Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
- Behavioral features in child and adolescent huntingtin gene‐mutation carriers
- Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1
- White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden
- Longitudinal changes in white matter as measured with diffusion tensor imaging in adult-onset myotonic dystrophy type 1
Showing 5 of 11 shared publications
- Associations between neurofilament light-chain protein, brain structure, and chronic kidney disease
- Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children
- <scp>Age‐Related</scp> Cognitive Changes as a Function of <scp>CAG</scp> Repeat in Child and Adolescent Carriers of Mutant Huntingtin
- Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
- Global and Regional White Matter Fractional Anisotropy in Children with Chronic Kidney Disease
Showing 5 of 10 shared publications
- Associations between neurofilament light-chain protein, brain structure, and chronic kidney disease
- Global and Regional White Matter Fractional Anisotropy in Children with Chronic Kidney Disease
- Neurocognitive deficits may not resolve following pediatric kidney transplantation
- Understanding the impact of pediatric kidney transplantation on cognition: A review of the literature
- Subsequent kidney transplant after pediatric heart transplant: Prevalence and risk factors
Showing 5 of 10 shared publications
- <scp>Age‐Related</scp> Cognitive Changes as a Function of <scp>CAG</scp> Repeat in Child and Adolescent Carriers of Mutant Huntingtin
- Neurocognitive deficits may not resolve following pediatric kidney transplantation
- Behavioral features in child and adolescent huntingtin gene‐mutation carriers
- Brain Developmental Trajectories in Children and Young Adults with Isolated Cleft Lip and/or Cleft Palate
- Brain structure and neural activity related to reading in boys with isolated oral clefts
Showing 5 of 8 shared publications
- Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children
- <scp>Age‐Related</scp> Cognitive Changes as a Function of <scp>CAG</scp> Repeat in Child and Adolescent Carriers of Mutant Huntingtin
- Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
- Behavioral features in child and adolescent huntingtin gene‐mutation carriers
- Neurofilament light protein as a blood biomarker for Huntington’s disease in children
Showing 5 of 7 shared publications
- Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1
- Quantitative muscle MRI as a sensitive marker of early muscle pathology in myotonic dystrophy type 1
- Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1
- White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden
- Longitudinal changes in white matter as measured with diffusion tensor imaging in adult-onset myotonic dystrophy type 1
Showing 5 of 6 shared publications
- Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1
- Clinical and neuroradiological correlates of sleep in myotonic dystrophy type 1
- Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1
- White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden
- Longitudinal changes in white matter as measured with diffusion tensor imaging in adult-onset myotonic dystrophy type 1
Showing 5 of 6 shared publications
- Cognitive Impairment in Survivors of Pediatric Acute Lymphoblastic Leukemia Treated With Chemotherapy Only
- Sex-Based Differences in Functional Brain Activity During Working Memory in Survivors of Pediatric Acute Lymphoblastic Leukemia
- Risk factors for neurocognitive impairment, emotional distress, and poor quality of life in survivors of pediatric rhabdomyosarcoma: A report from the Childhood Cancer Survivor Study
- Genetic variants, neurocognitive outcomes, and functional neuroimaging in survivors of childhood acute lymphoblastic leukemia
- Characterization of brain development with neuroimaging in a female mouse model of chemotherapy treatment of acute lymphoblastic leukemia
Showing 5 of 6 shared publications
- Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1
- Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1
- White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden
- Longitudinal changes in white matter as measured with diffusion tensor imaging in adult-onset myotonic dystrophy type 1
- Neurocognitive Features of Motor Premanifest Individuals With Myotonic Dystrophy Type 1
- Brain Imaging in Pediatric Cancer Survivors: Correlates of Cognitive Impairment
- Supplementary Information from Brain Development and Heart Function after Systemic Single-Agent Chemotherapy in a Mouse Model of Childhood Leukemia Treatment
- Supplementary Information from Brain Development and Heart Function after Systemic Single-Agent Chemotherapy in a Mouse Model of Childhood Leukemia Treatment
- Data from Brain Development and Heart Function after Systemic Single-Agent Chemotherapy in a Mouse Model of Childhood Leukemia Treatment
- Data from Brain Development and Heart Function after Systemic Single-Agent Chemotherapy in a Mouse Model of Childhood Leukemia Treatment
- Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
- Behavioral features in child and adolescent huntingtin gene‐mutation carriers
- Characterizing Early Changes in Quality of Life in Young Women With Breast Cancer
- Characterizing academic performance in pediatric acute lymphoblastic leukemia with population‐based achievement tests
- Author response for "Behavioral features in child and adolescent huntingtin gene-mutation carriers"
- Quantitative muscle MRI as a sensitive marker of early muscle pathology in myotonic dystrophy type 1
- Assisted annotation in Deep LOGISMOS: Simultaneous multi‐compartment 3D MRI segmentation of calf muscles
- Assisted annotation in Deep LOGISMOS: Combining deep learning and graph optimization for simultaneous multi-compartment 3D segmentation of calf muscles on MRI
- Assisted annotation in Deep LOGISMOS: Combining deep learning and graph optimization for simultaneous multi-compartment 3D segmentation of calf muscles on MRI
- Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
- Behavioral features in child and adolescent huntingtin gene‐mutation carriers
- Striatal Development in <scp>Early‐Onset</scp> Huntington's Disease
- Author response for "Behavioral features in child and adolescent huntingtin gene-mutation carriers"
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