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Biography and Research Information
OverviewAI-generated summary
Jacob M. Keck's research focuses on antimicrobial resistance and the development of new therapeutic strategies. His work has investigated treatment-emergent resistance to cefiderocol in carbapenem-resistant *Acinetobacter baumannii*, linking this resistance to the insertion sequence IS *Aba36* within the siderophore receptor *pirA*. Keck also examines antifungal resistance and the evaluation of antifungal stewardship initiatives, including the use of micafungin. His recent publications explore the challenges and approaches to managing fever in neutropenic patients, the emergence of resistance to new antibiotics, and case series utilizing novel antifungal agents like rezafungin for invasive candidiasis. He has also published on the use of combination therapies, such as aztreonam–avibactam with eravacycline, for complex bacterial infections. Keck's research network includes collaborators such as Ryan K. Dare and Alina Viteri at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 5
- Publications: 8
- Citations: 86
Selected Publications
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Use of Aztreonam–Avibactam with Rapid Eravacycline Step-Down Therapy for a Tibial Septic Non-Union by NDM-Producing Enterobacter cloacae (2025)
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“Dusting Off the Cobwebs”: Rethinking How We Use New Antibiotics (2025)
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It’s Here, It’s There, There’s Fungi Everywhere: A Case Series Utilizing Rezafungin for Invasive Candidiasis (2025)
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New Agents Are Coming, and So Is the Resistance (2024)
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Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i> (2024)
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Antifungal resistance, combinations and pipeline: oh my! (2023)
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Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center (2023)
Collaboration Network
Top Collaborators
David A. Cretella
Jackson Memorial Hospital (US)
3 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Antifungal resistance, combinations and pipeline: oh my!
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Katie E. Barber
University of Mississippi (US)
3 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Antifungal resistance, combinations and pipeline: oh my!
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Kayla R. Stover
University of Mississippi (US)
3 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Antifungal resistance, combinations and pipeline: oh my!
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Ryan K Dare
University of Arkansas for Medical Sciences
3 shared publications
In database
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
- It’s Here, It’s There, There’s Fungi Everywhere: A Case Series Utilizing Rezafungin for Invasive Candidiasis
- Use of Aztreonam–Avibactam with Rapid Eravacycline Step-Down Therapy for a Tibial Septic Non-Union by NDM-Producing Enterobacter cloacae
Alina Viteri
University of Arkansas for Medical Sciences
3 shared publications
In database
- New Agents Are Coming, and So Is the Resistance
- It’s Here, It’s There, There’s Fungi Everywhere: A Case Series Utilizing Rezafungin for Invasive Candidiasis
- “Dusting Off the Cobwebs”: Rethinking How We Use New Antibiotics
Mary Joyce B. Wingler
Jackson Memorial Hospital (US)
2 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Prakhar Vijayvargiya
Jackson Memorial Hospital (US)
2 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Jamie L. Wagner
University of Mississippi (US)
2 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Tulip A. Jhaveri
University of Mississippi Medical Center (US)
2 shared publications
- Approach to fever in patients with neutropenia: a review of diagnosis and management
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Rebekah N. Thompson
University of Arkansas Medical Center
2 shared publications
In database
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
- Use of Aztreonam–Avibactam with Rapid Eravacycline Step-Down Therapy for a Tibial Septic Non-Union by NDM-Producing Enterobacter cloacae
Zerelda Esquer Garrigos
University of Mississippi Medical Center (US)
1 shared publication
- Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center
Brandon Hawkins
University of Tennessee at Knoxville (US)
1 shared publication
- Antifungal resistance, combinations and pipeline: oh my!
En Huang
University of Arkansas for Medical Sciences (US)
1 shared publication
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
Sun Hee Moon
University of Arkansas for Medical Sciences (US)
1 shared publication
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
Michael S. Lowry
University of Arkansas for Medical Sciences (US)
1 shared publication
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
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