Jawahar L. Mehta
Distingusihed Professor
faculty
Internal Med, College of Medicine
Research Areas
Biography and Research Information
OverviewAI-generated summary
Jawahar L. Mehta, Distinguished Professor in Internal Medicine at the University of Arkansas for Medical Sciences, leads a research group that investigates cardiovascular diseases and their relationship with infectious diseases, including COVID-19. His work has examined various aspects of cardiovascular health, such as the role of NF-κB as a therapeutic target and the impact of loneliness and social isolation on cardiovascular outcomes. He has also focused on the implications of COVID-19, including meta-analyses on the efficacy of aspirin and colchicine for mortality and mechanical ventilation, and the analysis of cerebral venous sinus thrombosis following vaccination. Additionally, his research has touched upon HDL cholesterol levels and susceptibility to COVID-19, as well as concerns regarding myocarditis and pericarditis in adolescents following COVID-19 vaccination.
With a career marked by extensive publication, Mehta holds an h-index of 33 and has accrued over 6,749 citations across 144 publications. He is recognized as a highly cited researcher. His collaborations within the University of Arkansas for Medical Sciences include joint publications with Nishank Jain, Subhi J. Al’Aref, Srinivas Ayyadevara, and J. Curran Henson. His recent work also includes updates on new therapies for patients with chronic kidney disease (CKD).
Metrics
- h-index: 90
- Publications: 651
- Citations: 38,536
Selected Publications
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Disulfidptosis: A novel cell death mechanism with pathological significance and therapeutic potential in diseases (2026)
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Knowledge gaps in revascularization strategies in the setting of type II myocardial infarction: A common clinical dilemma in contemporary practices (2026)
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Functional Biochemistry of Iron and Its Cardiopulmonary Impact (2026)
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Remodelling-derived pre-β1 and remnant HDL particles: a snapshot of reverse cholesterol transport dynamics and efficiency (2025)
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Molecular Insights into Ischemia–Reperfusion Injury in Coronary Artery Disease: Mechanisms and Therapeutic Implications: A Comprehensive Review (2025)
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Addressing myocardial infarction in South-Asian populations: risk factors and machine learning approaches (2025)
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The pleiotropic effects of PCSK9 in cardiovascular diseases beyond cholesterol metabolism (2025)
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Reply (2024)
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Applications of ChatGPT in Heart Failure Prevention, Diagnosis, Management, and Research: A Narrative Review (2024)
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Positive Implications of Introducing Mindfulness Techniques as a Platform for Preoperative Stress Reduction to Improve Patient Outcomes Postpercutaneous Coronary Intervention (2024)
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‘Exerkines’: A Comprehensive Term for the Factors Produced in Response to Exercise (2024)
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COVID-19 in the Initiation and Progression of Atherosclerosis (2024)
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Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases (2024)
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Myosin light chain phosphatase is a downstream target of Rho-kinase in endothelin-1-induced transactivation of the TGF-β receptor (2024)
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The Interplay of Thiamine and Cardiovascular Diseases (2024)
Grants & Funding
- Anti-myeloma efficacy of FAP inhibitor in ex vivo and in vivo systems for primary myeloma Vantia Therapeutics Ltd. Principal Investigator
- Structure based drug design for atherosclerosis targeted at LOX-1, a receptor for oxidized low-density lipoprotein American Heart Association (SouthWest Affiliate) Co-Investigator
- Regulation of LOX-1 Expression by Pioglitazone Takeda Principal Investigator
- TOPCAT: Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone AnTagonist NIH/Nat. Heart, Lung & Blood Institute - Pass Through: New England Research Insts., Inc. Principal Investigator
- TOPCAT: Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone AnTagonist NIH/Nat. Heart, Lung & Blood Institute - Pass Through: New England Research Insts., Inc. Principal Investigator
Collaboration Network
Top Collaborators
- Cerebral Venous Sinus Thrombosis following COVID-19 Vaccination: Analysis of 552 Worldwide Cases
- COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis
- ‘Exerkines’: A Comprehensive Term for the Factors Produced in Response to Exercise
- Syndemic: A Synergistic Anthropological Approach to the COVID-19 Pandemic
- Does aspirin save lives in patients with COVID-19?
Showing 5 of 8 shared publications
- Cerebral Venous Sinus Thrombosis following COVID-19 Vaccination: Analysis of 552 Worldwide Cases
- COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis
- Syndemic: A Synergistic Anthropological Approach to the COVID-19 Pandemic
- Does aspirin save lives in patients with COVID-19?
- Letter in response to “<scp>COVID</scp>‐19, Virchow's triad and thromboembolic risk in obese pregnant women”
Showing 5 of 6 shared publications
- Updates on New Therapies for Patients with CKD
- Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Mesenchymal Stem Cell Treatment for Hyperactive Immune Response in Patients with COVID-19
- The Structural Basis of Effective LOX-1 Inhibition
Showing 5 of 6 shared publications
- NF-κB, A Potential Therapeutic Target in Cardiovascular Diseases
- Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
- NF-Κb, A Potential Therapeutic Target, In Cardiovascular Diseases
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases
Showing 5 of 6 shared publications
- HDL cholesterol levels and susceptibility to COVID-19
- COVID-19 in the Initiation and Progression of Atherosclerosis
- Prolactin Inhibition in Peripartum Cardiomyopathy: Systematic Review and Meta-analysis
- Vegetarianism, microbiota, and cardiovascular health: looking back, and forward
- Persistent cardiac injury – An important component of long COVID-19 syndrome
Showing 5 of 6 shared publications
- HDL cholesterol levels and susceptibility to COVID-19
- COVID-19 in the Initiation and Progression of Atherosclerosis
- Prolactin Inhibition in Peripartum Cardiomyopathy: Systematic Review and Meta-analysis
- Vegetarianism, microbiota, and cardiovascular health: looking back, and forward
- Persistent cardiac injury – An important component of long COVID-19 syndrome
Showing 5 of 6 shared publications
- Updates on New Therapies for Patients with CKD
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Potent Antiplatelet Therapy May Reduce Death from Sepsis in Patients on Chronic Dialysis
- Age Modifies Intracranial and Gastrointestinal Bleeding Risk from P2Y12 Inhibitors in Patients Receiving Dialysis
- 438 Platelets, Inflammation and Thrombosis in Chronic Kidney Disease
- Cerebral Venous Sinus Thrombosis following COVID-19 Vaccination: Analysis of 552 Worldwide Cases
- COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis
- Syndemic: A Synergistic Anthropological Approach to the COVID-19 Pandemic
- The long-term cardiovascular impairment of COVID 19: need for clarity in definition and terminology
- HDL cholesterol levels and susceptibility to COVID-19
- COVID-19 in the Initiation and Progression of Atherosclerosis
- Prolactin Inhibition in Peripartum Cardiomyopathy: Systematic Review and Meta-analysis
- Applications of ChatGPT in Heart Failure Prevention, Diagnosis, Management, and Research: A Narrative Review
- PEGylated Gold Nanoparticle Toxicity in Cardiomyocytes: Assessment of Size, Concentration, and Time Dependency
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Positive Implications of Introducing Mindfulness Techniques as a Platform for Preoperative Stress Reduction to Improve Patient Outcomes Postpercutaneous Coronary Intervention
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Potent Antiplatelet Therapy May Reduce Death from Sepsis in Patients on Chronic Dialysis
- Age Modifies Intracranial and Gastrointestinal Bleeding Risk from P2Y12 Inhibitors in Patients Receiving Dialysis
- Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
- Protein homeostasis in the aged and diseased heart
- Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
- Updates on New Therapies for Patients with CKD
- Molecular Insights into Ischemia–Reperfusion Injury in Coronary Artery Disease: Mechanisms and Therapeutic Implications: A Comprehensive Review
- Applications of ChatGPT in Heart Failure Prevention, Diagnosis, Management, and Research: A Narrative Review
- Meta-Analysis of the Effect of Aspirin on Mortality in COVID-19
- Meta-analysis of the Effect of Colchicine on Mortality and Mechanical Ventilation in COVID-19
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
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