Jennifer Chen

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University of Arkansas primary UAMS

Also affiliated: Rutgers, The State University of New Jersey (2023); Broad Institute (2021); Brigham Young University–Hawaii (2019); University of Vermont (2024); Brigham and Women's Hospital (2000–2011); San Francisco General Hospital (2023); The University of Sydney (2019–2024); Hartford Hospital (2010); Queensland Health (2022); University of Minnesota (2020–2021); San Francisco VA Medical Center (2006); Gladstone Institutes (2005–2006); University of Nevada, Reno (2001–2004); Harvard University (2001–2018); University of Connecticut (2010–2023); University of British Columbia (2008); Johns Hopkins University (2020); Central Connecticut State University (2019); University of Alberta (2016); Queensland University of Technology (2008); The University of Queensland (2025); University of California, San Francisco (2005–2023); Baylor College of Medicine (2023); University of Toronto (2004–2024); University of Washington (2024); Washington University in St. Louis (2008–2023); Cornell University (2017); University of Maryland Eastern Shore (2015); Brown University (2025); University of Michigan (2013); Royal Brisbane and Women's Hospital (2022–2025); Columbia University Irving Medical Center (2016); Great Ormond Street Hospital (2016); University of Minnesota System (2020); Lenox Hill Hospital (2011–2012); Hospital for Sick Children (2011–2016); Baylor University Medical Center (1993); Lankenau Medical Center (2024); Yale University (2018–2025); University of California San Diego (2023); Massachusetts General Hospital (2018); Blood Systems Research Institute (2006); University of California San Francisco Medical Center (2023); Saint Francis Hospital & Medical Center (2023); City Eye Centre (2008); Stanford Medicine (2023); Westmead Institute for Medical Research (2019–2024); Arkansas Children's Nutrition Center (2024–2025); AstraZeneca (United States) (2010); University of California Davis Medical Center (2006); Saint Louis University (2018); Drexel University (2012–2018); Rice University (2012); UConn Health (2023); Columbia University (2016–2022); University of Pennsylvania (2010–2025); University of California, Davis (2006–2022); The University of Texas at Austin (2023); The University of Texas Southwestern Medical Center (2010); University of California, Berkeley (2003); Stanford University (2023); McMaster University (2022–2023)

34 h-index 147 pubs 6,037 cited

Upstream record may be merged OpenAlex, the source of these figures, lists 64 institutions in 4 countries for this author record — a pattern that usually means it combines several researchers with similar names. The totals above may include work by other people.

Research Areas

Biomedical Subjects

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ORCID Research Group

OverviewAI-generated summary

Jennifer Chen's research focuses on understanding disease mechanisms and immune responses, with a significant portion of her recent work investigating SARS-CoV-2 infection and its impact. She has published studies on the cellular targets of SARS-CoV-2 in human airway epithelium, identifying alterations in gene expression and cell state changes. Further research has explored the role of nonsteroidal anti-inflammatory drugs in modulating the cytokine and antibody response to SARS-CoV-2, as well as the generation of high-affinity neutralizing antibodies in the absence of T follicular helper cells.

Beyond viral infections, Chen's research interests extend to other areas of human health. She has contributed to work on integrative oncogene-dependency mapping to identify vulnerabilities and synergies in lung cancer, and has investigated the role of Nox4 expression in osteo-progenitors during bone development in mice. Additionally, her work includes a systematic review on the efficacy of treatments in reducing inflammatory lesion count in rosacea. Chen leads a research group and has a substantial publication record, evidenced by an h-index of 34 and over 5,900 citations. She collaborates with researchers from the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences.

Metrics

h-index: 34
Publications: 147
Citations: 6,037

Selected Publications

Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications (2025)

The FASEB Journal 2 citations DOI OpenAlex
Soy Isoflavones Prevent Loss of Bone Quality Associated With High Fat Diet in Rats Through Ameliorating Epigenetic Modifications in Bone (2025)

Current Developments in Nutrition DOI OpenAlex
Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption (2025)

Cancers 1 citation DOI OpenAlex
Cystatin M/E ameliorates bone resorption through increasing osteoclastic cell estrogen influx (2024)

Research Square 1 citation DOI OpenAlex
Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice (2024)

The Journal of Nutritional Biochemistry 10 citations DOI OpenAlex
Nox4 expression in osteo-progenitors controls bone development in mice during early life (2022)

Communications Biology 18 citations DOI OpenAlex