Lemuel A. Brown Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
University of Arkansas at Fayetteville
faculty
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Biography and Research Information
OverviewAI-generated summary
Lemuel A. Brown's research program investigates mechanisms of skeletal muscle aging and regeneration. His work has explored how the cellular environment and molecular signaling pathways contribute to age-related changes in muscle tissue. This includes studying the role of pro-resolving mediators in skeletal muscle, and how deficiencies in these molecules may lead to maladaptive tissue remodeling.
Further research has focused on the behavior of muscle stem cells in aged mice, particularly in response to neuromuscular junction perturbations. Brown's publications also examine the influence of metabolic factors, such as diet-induced obesity, on extracellular matrix remodeling during muscle regeneration. Additionally, his work has investigated the impact of specific gene expressions, like PGC-1α, on the myogenic response, and explored biological sex differences in the development of fibrosis associated with cancer cachexia. Brown's scholarship metrics include an h-index of 23, 82 total publications, and 1,508 total citations, designating him as a highly cited researcher.
Metrics
- h-index: 23
- Publications: 82
- Citations: 1,508
Selected Publications
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023) DOI
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023) DOI
- Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration (2022) DOI
- The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration (2021) DOI
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