Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
J
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jeffrey A. Kamykowski's research focuses on the ultrastructural analysis of platelets and their role in thrombus formation and hemostasis. He utilizes advanced imaging techniques, including electron microscopy and deep learning-based analysis, to investigate the quantitative differences in platelet and organelle packing. His work has explored platelet behavior in various contexts, such as venous puncture wound hemostasis and the impact of COVID-19 on platelet structure. Kamykowski also trains image analysis techniques for characterizing cell phenotypes in microscopy images of mouse thrombi. His collaborations include extensive work with researchers at the University of Arkansas for Medical Sciences, such as Irina D. Pokrovskaya and Brian Storrie. Kamykowski has published 21 papers with 479 citations and an h-index of 9.
Metrics
- h-index: 9
- Publications: 21
- Citations: 506
Positions
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Core facilty tech 2010–presentUniversity of Arkansas for Medical Sciences Digital Microscopy Laboratory ORCID
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Research Tech 2008–2010University of Arkansas for Medical Sciences Physiology ORCID
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Clinical scientist 2006–2007Arkansas Childrens Hospital Clinical Laboratory -- microbiology ORCID
Selected Publications
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Murine thrombus organization limits access to high platelet activation states while supporting platelet recruitment (2026)
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Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation (2024)
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Trained image analysis techniques for characterizing cell phenotype in electron microscopy images of mouse thrombi (2024)
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Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets (2023)
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Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site (2023)
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Electron Microscope Characterization of Platelet Activation State Reveals That Wound Closure and P2Y 12 Receptors Are Major Early Determinants of Thrombus Structure in a Venous Puncture Model (2021)
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Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates (2021)
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Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape (2020)
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Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis (2020)
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Reduction in SNAP-23 Alters Microfilament Organization in Myofibrobastic Hepatic Stellate Cells (2019)
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3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets (2019)
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SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets (2018)
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The Alpha-Granule Release Reaction Is Mediated By SNARE-Dependent Solubilization of the Granule Matrix (2017)
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Managing the Introduction of Super-Resolution Microscopy into a Core Facility (2017)
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Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation (2016)
Collaboration Network
Top Collaborators
Brian Storrie
University of Arkansas for Medical Sciences
17 shared publications
In database
- Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet α-granules
- Electron <scp>T</scp>omography <scp>R</scp>eveals <scp>R</scp>ab6 <scp>I</scp>s <scp>E</scp>ssential to the <scp>T</scp>rafficking of <i>trans</i>‐<scp>G</scp>olgi <scp>C</scp>lathrin and <scp>COPI</scp>‐<scp>C</scp>oated <scp>V</scp>esicles and the <scp>M</scp>aintenance of <scp>G</scp>olgi <scp>C</scp>isternal <scp>N</scp>umber
- 3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets
- STEM tomography reveals that the canalicular system and α‐granules remain separate compartments during early secretion stages in blood platelets
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
Showing 5 of 17 shared publications
Irina D. Pokrovskaya
University of Arkansas for Medical Sciences
13 shared publications
In database
- 3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets
- STEM tomography reveals that the canalicular system and α‐granules remain separate compartments during early secretion stages in blood platelets
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
Showing 5 of 13 shared publications
Maria A. Aronova
National Institutes of Health (US)
11 shared publications
- 3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets
- STEM tomography reveals that the canalicular system and α‐granules remain separate compartments during early secretion stages in blood platelets
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
Showing 5 of 11 shared publications
Richard D. Leapman
National Institutes of Health (US)
11 shared publications
- 3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets
- STEM tomography reveals that the canalicular system and α‐granules remain separate compartments during early secretion stages in blood platelets
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
Showing 5 of 11 shared publications
Sidney W. Whiteheart
University of Kentucky (US)
7 shared publications
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
- Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis
- Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets
- The Alpha-Granule Release Reaction Is Mediated By SNARE-Dependent Solubilization of the Granule Matrix
Showing 5 of 7 shared publications
Smita Joshi
University of Kentucky (US)
5 shared publications
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
- Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis
- Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets
- The Alpha-Granule Release Reaction Is Mediated By SNARE-Dependent Solubilization of the Granule Matrix
Sung W. Rhee
University of Arkansas for Medical Sciences
5 shared publications
In database
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site
- Electron Microscope Characterization of Platelet Activation State Reveals That Wound Closure and P2Y 12 Receptors Are Major Early Determinants of Thrombus Structure in a Venous Puncture Model
- Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation
- Murine thrombus organization limits access to high platelet activation states while supporting platelet recruitment
Kelly K. Ball
University of Arkansas for Medical Sciences
5 shared publications
In database
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site
- Electron Microscope Characterization of Platelet Activation State Reveals That Wound Closure and P2Y 12 Receptors Are Major Early Determinants of Thrombus Structure in a Venous Puncture Model
- Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation
- Murine thrombus organization limits access to high platelet activation states while supporting platelet recruitment
Michael P. Tobin
National Institute of Biomedical Imaging and Bioengineering (US)
3 shared publications
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
- Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis
Rohan Desai
National Institute of Biomedical Imaging and Bioengineering (US)
3 shared publications
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
- Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis
Guofeng Zhang
National Institutes of Health (US)
3 shared publications
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape
- Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis
Oliver Zhao
National Institute of Biomedical Imaging and Bioengineering (US)
3 shared publications
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site
- Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation
Ngozi Wilkins
University of Arkansas for Medical Sciences (US)
2 shared publications
- Electron <scp>T</scp>omography <scp>R</scp>eveals <scp>R</scp>ab6 <scp>I</scp>s <scp>E</scp>ssential to the <scp>T</scp>rafficking of <i>trans</i>‐<scp>G</scp>olgi <scp>C</scp>lathrin and <scp>COPI</scp>‐<scp>C</scp>oated <scp>V</scp>esicles and the <scp>M</scp>aintenance of <scp>G</scp>olgi <scp>C</scp>isternal <scp>N</scp>umber
- Characterization of Platelet Alpha-Granule Dynamics
Guofeng Zhang
National Institute of Biomedical Imaging and Bioengineering (US)
2 shared publications
- 3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets
- SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets
Joshua Cohen
National Institutes of Health (US)
2 shared publications
- Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates
- Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site
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