Biography and Research Information

OverviewAI-generated summary

Kelly K. Ball's research investigates mechanisms of platelet activation and thrombus formation, particularly in the context of wound hemostasis and vascular injury. Their work has focused on characterizing the structure and evolution of thrombi using advanced imaging techniques, such as electron microscopy. Studies have examined how factors like platelet aggregation, receptor signaling (e.g., P2Y12, GPVI), and Syk inhibition influence thrombus development in venous and arterial models. Additionally, Ball has explored the implications of collateral artery function and therapeutic interventions, such as beta-blocker therapy, in a rat model of ischemic stroke. Ball has a publication record of 30 articles with 848 citations and an h-index of 13, indicating recent activity in the field.

Metrics

  • h-index: 13
  • Publications: 30
  • Citations: 848

Selected Publications

  • The Syk inhibitor BI 1002494 impairs thrombus infill in a murine femoral artery occlusion without affecting hemostasis (2025) DOI
  • Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure (2025) DOI
  • Differential Effects of GPVI Deletion and SYK Inhibition on Thrombus Organization and Platelet Adhesion in a Murine Jugular Puncture Wound Model (2024) DOI
  • Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation (2024) DOI
  • Puncture Wound Hemostasis and Preparation of Samples for Montaged Wide-Area Electron Microscopy Analysis (2024) DOI
  • JoVE Video Dataset (2024) DOI
  • Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site (2023) DOI
  • Electron Microscope Characterization of Platelet Activation State Reveals That Wound Closure and P2Y 12 Receptors Are Major Early Determinants of Thrombus Structure in a Venous Puncture Model (2021) DOI
  • Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates (2021) DOI
  • Mechanisms of Increased Infarct Volume in a Rat Model of Ischemic Stroke: Implications for Leptomeningeal Collateral Artery Function and Beta Blocker Therapy (2021) DOI

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