Match tier Listed
Presence Current · Arkansas
Last published 2021
Sources OpenAlex · ORCID
Refreshed 2026-08-08

John E. Seng

Researcher

Also affiliated: University of Minnesota (1997); Charles River Laboratories (United States) (2003–2010); University of Minnesota Medical Center (1998); Minnesota Oncology (2013–2017)

Faculty Researcher

16 h-index 28 pubs 887 cited

  • Animals
  • Male
  • Rats
  • Female
  • Mice
  • Dose-Response Relationship, Drug
  • Liver
  • Food Deprivation
  • Energy Intake
  • Carcinogenicity Tests
  • Humans
  • Aryl Hydrocarbon Hydroxylases
  • Rats, Sprague-Dawley
  • Body Weight
  • Chloral Hydrate

Biography and Research Information

OverviewAI-generated summary

John E. Seng is a faculty member at the University of Arkansas for Medical Sciences whose research focuses on the effects of radiation exposure on biological systems. His work has investigated the differential recovery of small intestinal segments following partial-body irradiation in non-human primates, as well as plasma metabolomics in primate models of abdominal radiation exposure. Seng has a scholarly h-index of 16, with 28 total publications and 884 citations. He has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Martin Hauer-Jensen, Rupak Pathak, Marjan Boerma, and Qiang Fu, on multiple publications.

Metrics

  • h-index: 16
  • Publications: 28
  • Citations: 887

Selected Publications

  • Plasma Metabolomics in a Nonhuman Primate Model of Abdominal Radiation Exposure (2021)
    Metabolites 2 citations DOI OpenAlex
  • Total Body Irradiation in the “Hematopoietic” Dose Range Induces Substantial Intestinal Injury in Non-Human Primates (2015)
    Radiation Research 33 citations DOI OpenAlex
  • Toxicokinetics of chloral hydrate in ad libitum-fed, dietary-controlled, and calorically restricted male B6C3F1 mice following short-term exposure (2003)
    Toxicology and Applied Pharmacology 17 citations DOI OpenAlex
  • Dietary controlled carcinogenicity study of chloral hydrate in male B6C3F1 mice (2003)
    Toxicology and Applied Pharmacology 26 citations DOI OpenAlex
  • Body weight considerations in the B6C3F1 mouse and the use of dietary control to standardize background tumor incidence in chronic bioassays (2003)
    Toxicology and Applied Pharmacology 23 citations DOI OpenAlex
  • A Mechanistic Basis for the Beneficial Effects of Caloric Restriction On Longevity and Disease: Consequences for the Interpretation of Rodent Toxicity Studies (1998)
    International Journal of Toxicology 24 citations DOI OpenAlex
  • FDA Points-to-Consider Documents: The Need for Dietary Control for the Reduction of Experimental Variability within Animal Assays and the Use of Dietary Restriction to Achieve Dietary Control (1996)
    Toxicologic Pathology 43 citations DOI OpenAlex
  • Effects of Caloric Restriction on Expression of Testicular Cytochrome P450 Enzymes Associated with the Metabolic Activation of Carcinogens (1996)
    Archives of Biochemistry and Biophysics 34 citations DOI OpenAlex
  • Purification and characterization of an amidase from an acrylamide-degrading Rhodococcus sp (1994)
    Applied and Environmental Microbiology 75 citations DOI OpenAlex
  • Effects of caloric restriction on rodent drug and carcinogen metabolizing enzymes: implications for mutagenesis and cancer (1993)
    Mutation Research/DNAging 57 citations DOI OpenAlex
  • Cellular Localization of Cytochrome P45011A1 in Testes of Mature Sprague-Dawley Rats1 (1991)
    Biology of Reproduction 14 citations DOI OpenAlex
  • Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine (1991)
    Toxicology and Applied Pharmacology 21 citations DOI OpenAlex

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Collaboration Network

8 Collaborators 2 Institutions 1 Country

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