Jyotshna Kanungo Data-verified
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Senior (Principal) Investigator
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Biography and Research Information
OverviewAI-generated summary
Jyotshna Kanungo's research investigates the neurotoxicological effects of environmental agents, with a particular focus on zebrafish as a model organism. Her work examines how substances like inorganic arsenic impact neuronal development, including dopaminergic, serotonergic, and motor neurons. Kanungo has explored the mechanisms by which arsenic induces apoptosis and alters gene expression in zebrafish embryos, with some investigations drawing parallels to modeling conditions such as autism. Additionally, her research has delved into the potential antidepressant actions of ketamine, exploring its effects on gene expression and the role of L-type calcium channels. Kanungo also contributes to the development of screening tools for assessing the neurotoxic potential of botanicals and has published on advanced techniques for neurotoxicity assessments, such as combining tissue clearing with specific labeling methods. Her scholarship metrics include an h-index of 19, with 46 total publications and 961 total citations. She has collaborated extensively with colleagues at the National Center for Toxicological Research.
Metrics
- h-index: 19
- Publications: 51
- Citations: 988
Selected Publications
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Special Issue “Zebrafish: A Model Organism for Human Health and Disease” (2025)
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Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development (2025)
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Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety (2024)
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Neurogenic Effects of Inorganic Arsenic and Cdk5 Knockdown in Zebrafish Embryos: A Perspective on Modeling Autism (2024)
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Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish (2023)
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Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments (2023)
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Use of zebrafish embryos to study molecular and cellular neurotoxic effects of drugs: A focus on signaling and ketamine (2022)
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Effect of ketamine on gene expression in zebrafish embryos (2021)
Collaboration Network
Top Collaborators
- Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish
- Antidepressant Actions of Ketamine: Potential Role of L-Type Calcium Channels
- Effect of ketamine on gene expression in zebrafish embryos
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Neurogenic Effects of Inorganic Arsenic and Cdk5 Knockdown in Zebrafish Embryos: A Perspective on Modeling Autism
Showing 5 of 6 shared publications
- Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish
- Antidepressant Actions of Ketamine: Potential Role of L-Type Calcium Channels
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
- Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
- Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
- Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
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