Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
J
Jyotshna Kanungo
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Senior (Principal) Investigator
Also affiliated: National Institutes of Health (2006–2018); United States Food and Drug Administration (2011–2026); Augusta University (1993–1996); National Institute of Neurological Disorders and Stroke (2006–2018); Bentham Science Publishers (United Arab Emirates) (2014)
19 h-index
52 pubs
1,008 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jyotshna Kanungo's research focuses on understanding the neurodevelopmental and neurotoxic effects of environmental agents, utilizing zebrafish as a model organism. Her work investigates how substances like inorganic arsenic and ketamine impact neural development and function, with implications for human health conditions including autism and depression. Kanungo has explored the molecular mechanisms underlying arsenic-induced neurotoxicity, examining its effects on dopaminergic and motor neurons, and its potential involvement with the Sonic hedgehog pathway. She has also studied the antidepressant actions of ketamine, with a focus on the role of L-type calcium channels and gene expression changes in zebrafish embryos.
Her research employs advanced techniques for neurotoxicity assessment, such as combining tissue clearing with Fluoro-Jade C labeling. Kanungo's publication record includes work on screening tools for evaluating the neurotoxic potential of botanicals. Her scholarship metrics include an h-index of 19, with 52 total publications and 996 total citations. She collaborates with researchers at the National Center for Toxicological Research, including Qiang Gu, Nathan C. Twaddle, Frederick A. Beland, and Camila Silva.
Metrics
- h-index: 19
- Publications: 52
- Citations: 1,008
Positions
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Senior (Principal) Investigator publications 2011–2026National Center for Toxicological Research Division of Neurotoxicology Division of Neurotoxicology ORCID
Selected Publications
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A new method for visualizing cerebrovascular vessels (2026)
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N-Acetylcysteine Prevents Arsenic-Induced Apoptosis but Not Supernumerary Motor Neuron Development in Zebrafish Embryos: Assessment of Protein Carbonylation and the p53 Pathway (2026)
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Special Issue “Zebrafish: A Model Organism for Human Health and Disease” (2025)
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Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development (2025)
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Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety (2024)
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Neurogenic Effects of Inorganic Arsenic and Cdk5 Knockdown in Zebrafish Embryos: A Perspective on Modeling Autism (2024)
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Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish (2023)
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Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments (2023)
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Use of zebrafish embryos to study molecular and cellular neurotoxic effects of drugs: A focus on signaling and ketamine (2022)
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Effect of ketamine on gene expression in zebrafish embryos (2021)
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Effects of acetyl L‐carnitine on zebrafish embryos: Phenotypic and gene expression studies (2020)
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N-acetylcysteine prevents verapamil-induced cardiotoxicity with no effect on the noradrenergic arch-associated neurons in zebrafish (2020)
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Cell & Developmental Biology (2019)
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Nifedipine toxicity is exacerbated by acetyl l ‐carnitine but alleviated by low‐dose ketamine in zebrafish in vivo (2019)
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Downregulation of 14-3-3 Proteins in Alzheimer’s Disease (2019)
Collaboration Network
Top Collaborators
Qiang Gu
National Center for Toxicological Research
17 shared publications
In database
- Downregulation of 14-3-3 Proteins in Alzheimer’s Disease
- Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish
- Mechanistic studies on ketamine-induced mitochondrial toxicity in zebrafish embryos
- Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model
- Ketamine-induced attenuation of reactive oxygen species in zebrafish is prevented by acetyl l-carnitine in vivo
Showing 5 of 17 shared publications
Syed F. Ali
National Center for Toxicological Research
15 shared publications
In database
- Developmental toxicity assay using high content screening of zebrafish embryos
- Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish
- Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles
- Acetyl l-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos
- l-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos
Showing 5 of 15 shared publications
Merle G. Paule
National Center for Toxicological Research
15 shared publications
In database
- Developmental toxicity assay using high content screening of zebrafish embryos
- Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish
- Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles
- Acetyl l-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos
- In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos
Showing 5 of 15 shared publications
Bonnie Robinson
National Center for Toxicological Research
11 shared publications
In database
- Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles
- Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish
- Mechanistic studies on ketamine-induced mitochondrial toxicity in zebrafish embryos
- Ketamine-induced attenuation of reactive oxygen species in zebrafish is prevented by acetyl l-carnitine in vivo
- Cyclosporine exacerbates ketamine toxicity in zebrafish: Mechanistic studies on drug–drug interaction
Showing 5 of 11 shared publications
Melanie Dumas
Bionetics (United States) (US)
9 shared publications
- Developmental toxicity assay using high content screening of zebrafish embryos
- Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish
- Mechanistic studies on ketamine-induced mitochondrial toxicity in zebrafish embryos
- Ketamine-induced attenuation of reactive oxygen species in zebrafish is prevented by acetyl l-carnitine in vivo
- Cyclosporine exacerbates ketamine toxicity in zebrafish: Mechanistic studies on drug–drug interaction
Showing 5 of 9 shared publications
Elvis Cuevas
National Center for Toxicological Research (US)
8 shared publications
- Developmental toxicity assay using high content screening of zebrafish embryos
- Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish
- Downregulation of 14-3-3 Proteins in Alzheimer’s Disease
- Acetyl l-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos
- l-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos
Showing 5 of 8 shared publications
Xiaoqing Guo
National Center for Toxicological Research
5 shared publications
In database
- Developmental toxicity assay using high content screening of zebrafish embryos
- Acetyl l-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos
- Ketamine attenuates cytochrome p450 aromatase gene expression and estradiol‐17β levels in zebrafish early life stages
- Nicotine alters the expression of molecular markers of endocrine disruption in zebrafish
- Acetyl L ‐carnitine targets adenosine triphosphate synthase in protecting zebrafish embryos from toxicities induced by verapamil and ketamine: An in vivo assessment
William J. Trickler
National Center for Toxicological Research (US)
4 shared publications
- Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles
- Acetyl l-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos
- Ketamine attenuates cytochrome p450 aromatase gene expression and estradiol‐17β levels in zebrafish early life stages
- Nicotine alters the expression of molecular markers of endocrine disruption in zebrafish
Sumit Sarkar
National Center for Toxicological Research
4 shared publications
In database
- Downregulation of 14-3-3 Proteins in Alzheimer’s Disease
- Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model
- Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments
- A new method for visualizing cerebrovascular vessels
Camila Silva
National Center for Toxicological Research
3 shared publications
In database
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
- N-Acetylcysteine Prevents Arsenic-Induced Apoptosis but Not Supernumerary Motor Neuron Development in Zebrafish Embryos: Assessment of Protein Carbonylation and the p53 Pathway
Nathan C. Twaddle
National Center for Toxicological Research
3 shared publications
In database
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
- N-Acetylcysteine Prevents Arsenic-Induced Apoptosis but Not Supernumerary Motor Neuron Development in Zebrafish Embryos: Assessment of Protein Carbonylation and the p53 Pathway
Frederick A. Beland
National Center for Toxicological Research
3 shared publications
In database
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
- N-Acetylcysteine Prevents Arsenic-Induced Apoptosis but Not Supernumerary Motor Neuron Development in Zebrafish Embryos: Assessment of Protein Carbonylation and the p53 Pathway
Susan M. Lantz-McPeak
National Center for Toxicological Research (US)
2 shared publications
- Developmental toxicity assay using high content screening of zebrafish embryos
- Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles
Harish C. Pant
National Institute of Neurological Disorders and Stroke (US)
2 shared publications
- A 24-Residue Peptide (p5), Derived from p35, the Cdk5 Neuronal Activator, Specifically Inhibits Cdk5-p25 Hyperactivity and Tau Hyperphosphorylation
- Notch and Cdk5 in Zebrafish mindbomb Mutant: Co-regulation or Coincidence?
James Raymick
National Center for Toxicological Research
2 shared publications
In database
- Downregulation of 14-3-3 Proteins in Alzheimer’s Disease
- Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model
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