Lane Smith

Researcher

University of Arkansas for Medical Sciences

faculty

5 h-index 7 pubs 305 cited

Research Areas

DNA Repair Mechanisms Protein Structure and Dynamics Cancer-related molecular mechanisms research Molecular Biology Techniques and Applications Bioinformatics and Genomic Networks

Links

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OverviewAI-generated summary

Lane Smith's research focuses on the molecular mechanisms underlying DNA repair and replication, particularly concerning the function of the Human Rev1 protein. Smith's work has investigated how Human Rev1 interacts with specific DNA structures, such as G-quadruplex motifs. Recent publications highlight the role of an insert region unique to higher eukaryotes in mediating selective binding of Human Rev1 to these motifs, suggesting a mechanism for accurate replication of stabilized G-quadruplexes. Smith has collaborated with researchers at the University of Arkansas for Medical Sciences, including Amit Ketkar, Robert L. Eoff, Megan R. Reed, and Leena Maddukuri, on shared publications. Smith's scholarly output includes 7 publications with an h-index of 5 and over 300 citations, with recent activity noted in 2021.

Metrics

  • h-index: 5
  • Publications: 7
  • Citations: 305

Selected Publications

  • Selective Binding Of Human Rev1 With G‐Quadruplex DNA Is Determined By A Region Unique to Higher Eukaryotes (2021) DOI
  • Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs (2021) DOI

Collaborators

Researchers in the database who share publications

Amit Ketkar University of Arkansas for Medical Sciences 2 shared publications Robert L. Eoff University of Arkansas for Medical Sciences 2 shared publications Megan R. Reed University of Arkansas for Medical Sciences 2 shared publications Leena Maddukuri University of Arkansas for Medical Sciences 2 shared publications Julie Gunderson Hendrix College 2 shared publications

Similar Researchers

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Robert Eoff University of Arkansas for Medical Sciences
DNA Repair Mechanisms Protein Structure and Dynamics Cancer-related molecular mechanisms research
Good match 4 shared topics