Laura Marcu
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Professor
Also affiliated: University of Southern California (1994–2008); Dartmouth Institute for Health Policy and Clinical Practice (2025); Cedars-Sinai Medical Center (1994–2006); LAC+USC Medical Center (2006); University of California, Los Angeles (2001); California Southern University (1998–2006); West Health (2015); University of California System (2008–2025); Valahia University of Targoviste (2022); Dartmouth Psychiatric Research Center (2025); Med Center (2005); Neurological Surgery (2009–2025); Institute of Biomedical Science (2022); University of California Davis Medical Center (2020); Ukrainian Catholic University (2020); University of California, Davis (2005–2025)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Laura Marcu's research focuses on the development and clinical application of label-free optical spectroscopy and imaging technologies for tissue diagnostics and image-guided interventions. Her work integrates advanced instrumentation with signal processing and artificial intelligence to enable real-time tissue characterization. She has pioneered clinical applications of fluorescence lifetime imaging (FLIM), including first-in-human intraoperative studies for brain and head-and-neck cancers.
Dr. Marcu has also developed multimodal FLIM-IVUS and FLIm-PSOCT systems for in vivo intravascular imaging. Her research has led to publications on mesoscopic fluorescence lifetime imaging, multispectral FLIM devices, and hybrid intracoronary imaging technologies. She has investigated the in vivo characterization of glioblastoma using label-free intraoperative FLIM and developed anatomy-specific classification models for surgical guidance in head and neck cancer.
Her scholarly output includes 336 publications, with an h-index of 46 and over 6,500 citations. She holds an Endowed Professorship of Neurosurgery Research at UC Davis and directs the Biophotonics Laboratory. She also serves as Founding Director of the NIH-NIBIB P41 National Center for Interventional Biophotonic Technologies (NCIBT) and Co-Director of the Biomedical Technology Program at the UC Davis Comprehensive Cancer Center.
Metrics
- h-index: 46
- Publications: 336
- Citations: 6,527
Selected Publications
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Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling (2025)
Collaboration Network
Top Collaborators
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
- Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
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