Laura R. Osborn

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UAMS

Also affiliated: Ave Maria University (2020); Arkansas Children's Research Institute (2024–2026)

2 h-index 16 pubs 26 cited

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Biomedical Subjects

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ORCID

OverviewAI-generated summary

Laura R. Osborn's research investigates the effects of early-life stress on offspring bone health, with a particular focus on the period of lactation. Her work also examines the development of peripheral neuropathy in animal models, specifically mice and rats, and its association with factors such as myelin degradation and cold hypersensitivity. Osborn's laboratory has explored metabolic profiling to understand the impact of early-life stress following peripheral nerve injury and the consequent changes in gut microbiome composition. Her publications include studies on meloxicam bioactivation, paclitaxel-induced peripheral neuropathy, and the metabolism of synthetic cannabinoids. Osborn holds an h-index of 2 with 16 total publications and 26 citations. She has collaborated with researchers including Mary Grace Bishop, Kayleigh Amber Rodriguez, Dakota Redling, and Grover P. Miller, all from the University of Arkansas for Medical Sciences.

Metrics

h-index: 2
Publications: 16
Citations: 26

Selected Publications

Degraded myelin is associated with cold hypersensitivity in paclitaxel-induced peripheral neuropathy (2026)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Impact of Early Life Stress on the Composition of Gut Microbiome (2026)

Journal of Pain DOI OpenAlex
Myelin Degradation as a Driver of Persistent, Exclusive Cold Hypersensitivity in a Model of Chemotherapy-Induced Peripheral Neuropathy (2026)

Journal of Pain DOI OpenAlex
A Novel Model of Paclitaxel-Induced Peripheral Neuropathy Produces a Clinically Relevant Phenotype in Mice (2026)

Current Neuropharmacology 2 citations DOI OpenAlex
Stress During Lactation: A Hidden Link to Offspring Bone Health (2025)

Calcified Tissue International 1 citation DOI OpenAlex
Impact of Maternal Care Behaviors on Mechanical Sensitivity of Adult Offspring (2025)

Journal of Pain DOI OpenAlex
Effect of Early Life Stress on Skeletal Health (2024)

Current Developments in Nutrition DOI OpenAlex
Behavioral Effects of Repeated Paclitaxel Cycles on Paclitaxel-Induced Peripheral Neuropathy Resolution (2024)

Journal of Pain DOI OpenAlex
The Persistence Of Rodent Mechanical Hypersensitivity Following Chronic Constriction Injury From Chronic Early-Life Stress (2024)

Journal of Pain DOI OpenAlex
Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes (2022)

Metabolites 2 citations DOI OpenAlex
Methamphetamine‐Induced Proteomic Changes Within the Neuroinflammatory TLR4 Pathway Persist After Long‐Term Self‐Administration in Rats (2022)

The FASEB Journal DOI OpenAlex
Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam (2020)

Toxicology 20 citations DOI OpenAlex