Lauren Appell

Sourced from institutional research profiles (UAMS TRI or ARA).

Physician

UAMS

Also affiliated: Arkansas Children's Hospital (2021–2026); University of Arkansas Medical Center (2025); University of Alabama at Birmingham (2014)

Faculty Researcher

2 h-index 14 pubs 17 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group UAMS TRI Profile

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OverviewAI-generated summary

Lauren Appell's research focuses on various aspects of pediatric hematology and oncology, with recent publications investigating T-cell activation and cytotoxicity in relation to DNA-PKcs inhibition. Appell has also studied rare conditions, including GATA2 deficiency presenting as recalcitrant warts in an adolescent, and CAR-T cell therapy for post-transplant lymphoproliferative disorder in a pediatric heart transplant recipient. Other work includes exploring late complications of hematopoietic stem cell transplantation (HSCT) such as inflammatory myositis, and investigating causes of fever of unknown origin post-bone marrow transplant (BMT), including HHV-6 encephalitis. Appell's research also extends to clinical interventions, such as the STRONGER ALL study evaluating an exercise regimen for pediatric acute lymphoblastic leukemia patients and the use of granulocyte infusions for pediatric hematology/oncology patients with severe neutropenia and fungal infections. Appell's scholarly output includes 14 publications with an h-index of 2, and collaborations with Jason E. Farrar, JM Mack, Ana Clara P. Azevedo‐Pouly, and Melanie Barker.

Metrics

h-index: 2
Publications: 14
Citations: 17

Selected Publications

Feasibility of Non-Sedated Multispectral Neuroimaging in Newly Diagnosed Children with Leukemia (2026)

medRxiv DOI OpenAlex
Central nervous system-symptomatic hyperammonemia following recombinant crisantaspase Pseudomonas fluorescens (2026)

The American Journal of the Medical Sciences DOI OpenAlex
A supervised STreNgth & Outpatient Exercise Regimen in pediatric patients with Acute Lymphoblastic Leukemia (STRONGER ALL) (2026)

The American Journal of the Medical Sciences DOI OpenAlex
From cornstarch to crisis: thiamine deficiency following pegylated asparaginase induced hypoglycemia in infant B-ALL (2026)

The American Journal of the Medical Sciences DOI OpenAlex
Clinical conundrum: solving the mystery (2026)

The American Journal of the Medical Sciences DOI OpenAlex
Liberalizing hospital proximity requirements for children/young adults with low-burden B-ALL receiving tisagenlecleucel (2025)

Blood Advances DOI OpenAlex
130 A supervised strength and outpatient exercise regimen in pediatric patients with acute lymphoblastic leukemia (STRONGER ALL) (2025)

Journal of Clinical and Translational Science DOI OpenAlex
Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency (2024)

Journal of Allergy and Clinical Immunology Global 1 citation DOI OpenAlex
Inhibition of DNA-Pkcs As Novel Therapy for the Prevention of Acute Gvhd Following Hematopoietic Stem Cell Transplantation (2021)

Blood DOI OpenAlex