Mari Davidson
Sourced from institutional research profiles (UAMS TRI or ARA).
Associate Professor
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Mari Davidson's research investigates fundamental biological processes, with a significant portion of her work focusing on cell adhesion molecules and genetic recombination. Her early publications explored the diverse roles of cadherins, a family of cell adhesion proteins critical for tissue development and function, examining their expression in human osteoblasts and their connection to bone formation. Further work delved into protocadherins, characterizing their distinct properties compared to classical cadherins and their presence in the central nervous system.
More recently, Davidson's research has focused on the molecular mechanisms of meiosis, specifically the role of proteins like Rec12 (Spo11) in recombination and chromosome segregation in the yeast *Schizosaccharomyces pombe*. This work has elucidated distinct requirements for these proteins in different stages of meiosis. Her research group also investigates gene expression and protein interactions, including studies on epidermal growth factor receptor and its role in tissue regeneration, as well as the interaction between human cytomegalovirus proteins and host cellular machinery.
With an h-index of 23 and over 1,700 citations across 51 publications, Davidson has made substantial contributions to molecular biology and genetics. Her recent activity indicates ongoing research in these areas.
Metrics
- h-index: 23
- Publications: 51
- Citations: 1,722
Positions
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Associate Professor 2002–presentUniversity of Arkansas for Medical Sciences Biochemistry and Molecular Biology Institutional directory
Selected Publications
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Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024)
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Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions (2024)
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Laboratory horror stories: Poison in the agars (2024)
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Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution (2022)
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Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways (2022)
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Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination (2021)
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Molecular mechanisms for environmentally induced plasticity in the positioning of meiotic recombination at hotspots (2020)
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Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast (2019)
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Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway (2019)
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The Syphilis Testing Result Interprofessional Counseling and Education (STRICE) simulation (2019)
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Incorporating Interprofessional Education to Distance Curricula Through Online Simulation: A Pilot Project (2018)
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Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot (2018)
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Proteomic analysis of a meiotic recombination hotspot (2016)
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Nonsense codon suppression in fission yeast due to mutations of tRNASer.11 and translation release factor Sup35 (eRF3) (2014)
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A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs (2013)
Grants & Funding
As listed on this researcher's institutional profile.
- Biochemistry of recombination in meiosis NIH
- Molecular mechanisms of aneuploidy NIH
- CADHERIN 5 AND ENDOTHELIAL JUNCTION NIH
Collaboration Network
Top Collaborators
- Distinct functions of S. pombeRec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II
- Atf1-Pcr1-M26 Complex Links Stress-activated MAPK and cAMP-dependent Protein Kinase Pathways via Chromatin Remodeling of cgs2+
- Discrete DNA sites regulate global distribution of meiotic recombination
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Meiotic Recombination Hotspots of Fission Yeast Are Directed to Loci that Express Non-Coding RNA
Showing 5 of 27 shared publications
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
Showing 5 of 9 shared publications
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast
- Phosphorylation-Independent Regulation of Atf1-Promoted Meiotic Recombination by Stress-Activated, p38 Kinase Spc1 of Fission Yeast
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- Regulation of meiotic recombination by a multifunctional ATF/CREB protein
Showing 5 of 7 shared publications
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
- Laboratory horror stories: Poison in the agars
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
- Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast
- Nonsense codon suppression in fission yeast due to mutations of tRNASer.11 and translation release factor Sup35 (eRF3)
- Proteomic analysis of a meiotic recombination hotspot
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
- Distinct functions of S. pombeRec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II
- Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast
- A DNA binding motif of meiotic recombinase Rec12 (Spo11) defined by essential glycine-202, and persistence of Rec12 protein after completion of recombination
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway
- Molecular mechanisms for environmentally induced plasticity in the positioning of meiotic recombination at hotspots
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- Proteomic analysis of a meiotic recombination hotspot
- The Syphilis Testing Result Interprofessional Counseling and Education (STRICE) simulation
- Incorporating Interprofessional Education to Distance Curricula Through Online Simulation: A Pilot Project
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