Aaron J. Storey
Researcher
Also affiliated: Arkana Laboratories (2022–2026); Arkansas Department of Agriculture (2014)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Aaron J. Storey's research focuses on the molecular mechanisms underlying cancer development and the identification of novel therapeutic targets. His work investigates how aberrant cellular processes, such as phase separation and chromatin looping, contribute to tumorigenesis. Storey has published studies on the role of specific proteins, including NSD3 and HTRA1, in cancer and kidney disease, exploring their potential as therapeutic targets. He has also investigated the use of proteolysis-targeting chimeras (PROTACs) for cancer treatment, including the discovery of dual WDR5 and Ikaros PROTAC degraders.
His recent publications explore the regulatory axis of YY1 in advanced prostate cancer and the engagement of histone modifications in silencing endogenous retroviruses. Storey's research employs techniques such as mass spectrometry to identify novel antigens in membranous nephropathy and utilizes cistrome analysis to understand gene regulation in cancer. He maintains a collaborative network with researchers at the University of Arkansas for Medical Sciences, including Samuel G. Mackintosh, Alan J. Tackett, Sydnye L. Shuttleworth, and Fenghuang Zhan, with whom he has co-authored numerous publications.
Storey's scholarship metrics include an h-index of 23, with over 2,018 citations across 135 publications, indicating a significant body of work in his field. He is recognized as a highly cited researcher.
Metrics
- h-index: 24
- Publications: 145
- Citations: 2,066
Selected Publications
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication (2025)
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The phenylalanine-and-glycine repeats of NUP98 oncofusions form condensates that selectively partition transcriptional coactivators (2025)
Collaboration Network
Top Collaborators
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 17 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 16 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 15 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 10 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 10 shared publications
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Characterization of methionine dependence in melanoma cells
Showing 5 of 8 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
Showing 5 of 7 shared publications
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
Showing 5 of 6 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
Showing 5 of 6 shared publications
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
- The phenylalanine-and-glycine repeats of NUP98 oncofusions form condensates that selectively partition transcriptional coactivators
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
Showing 5 of 6 shared publications
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Proprotein convertase subtilisin/kexin type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use
- The Alternative Pathway Is Necessary and Sufficient for Complement Activation by Anti-THSD7A Autoantibodies, Which Are Predominantly IgG4 in Membranous Nephropathy
Showing 5 of 6 shared publications
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Proprotein convertase subtilisin/kexin type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use
- Cubilin and amnionless protein are novel target antigens in anti–brush border antibody disease
- Phase separation drives aberrant chromatin looping and cancer development
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- The phenylalanine-and-glycine repeats of NUP98 oncofusions form condensates that selectively partition transcriptional coactivators
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- Phase separation drives aberrant chromatin looping and cancer development
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
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