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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
Wayne P. Wahls
Federal Grant PI
High Impact
Professor
Also affiliated: Vanderbilt University (1997–1999); University of Illinois Chicago (1990–1991); Fred Hutch Cancer Center (1993–1997)
Biochemistry & Molecular Biology, College of Medicine
26 h-index
84 pubs
2,260 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Wayne P. Wahls, Professor in Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences, investigates fundamental mechanisms of genetic recombination and gene expression. His research group has explored the roles of specific DNA sequences, such as hypervariable minisatellites and Z-DNA motifs, in promoting homologous recombination and gene conversion events in human cells. Studies have also examined the involvement of chromatin remodeling factors and transcription factors in regulating meiotic recombination hotspots, particularly in the fission yeast *Schizosaccharomyces pombe*.
Wahls' work has contributed to understanding the function of proteins like Rec12 (Spo11) in meiotic recombination and chromosome segregation. He has also developed and applied molecular biology techniques, including CRISPR-based approaches for proteomic analysis of genomic loci. His research has been supported by federal grants, including a $423,218 award from the NIH/National Institute of General Medical Sciences for the systematic elucidation of DNA sequence codes regulating meiotic recombination. Wahls is recognized as a highly cited researcher, with a h-index of 26 and over 2,250 citations across his 84 publications. He actively collaborates with researchers within the University of Arkansas system and beyond.
Metrics
- h-index: 26
- Publications: 84
- Citations: 2,260
Positions
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University of Arkansas for Medical Sciences 2002–presentORCID
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Professor publications 2002–2026University of Arkansas for Medical Sciences Biochemistry & Molecular Biology, College of Medicine Institutional directory
Selected Publications
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe (2025)
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Targeted Forward Genetics: Saturating Mutational Analyses of Specific Target Loci Within the Genome (2024)
Federal Grants 1 $423,218 total
NIH
Contact PI
May 2022 - Mar 2027
Systematic elucidation of DNA sequence codes that regulate meiotic recombination
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Combinatoial CREB/ATF dimers and cellular growth control NIH Principal Investigator
- Transcription-coupled Homologous Recombination Human Frontier Science Program Principal Investigator
- Center for Molecular Interactions in Cancer (CMIC) NIH Co-Investigator
- Biochemistry of recombination in meiosis NIH Principal Investigator
- HOMOLOGUS RECOMBINATION HOTSPOTS NIH Principal Investigator
- REGULATION OF MEIOTIC DEVELOPMENT BY MTS1-MTS2 PROTEIN NIH Principal Investigator
- Molecular mechanisms of aneuploidy NIH Co-Investigator
- Wahls start up account UAMS College of Medicine Principal Investigator
Collaboration Network
Top Collaborators
Mari K. Davidson
27 shared publications
In database
- Distinct functions of S. pombeRec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II
- Atf1-Pcr1-M26 Complex Links Stress-activated MAPK and cAMP-dependent Protein Kinase Pathways via Chromatin Remodeling of cgs2+
- Discrete DNA sites regulate global distribution of meiotic recombination
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Meiotic Recombination Hotspots of Fission Yeast Are Directed to Loci that Express Non-Coding RNA
Showing 5 of 27 shared publications
Aaron J. Storey
University of Arkansas for Medical Sciences
22 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- In Vivo Metabolic Tracing Demonstrates the Site‐Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
Showing 5 of 22 shared publications
Stephanie D. Byrum
University of Arkansas for Medical Sciences
16 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 16 shared publications
Jeffrey A. Lewis
University of Arkansas at Fayetteville
15 shared publications
In database
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 15 shared publications
Samuel G. Mackintosh
University of Arkansas for Medical Sciences
14 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 14 shared publications
Rick D. Edmondson
University of Arkansas for Medical Sciences
13 shared publications
In database
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
Rebecca E. Hardman-Kavanaugh
University of Arkansas at Fayetteville
13 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
Tara Stuecker
University of Arkansas at Fayetteville
13 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
Stephanie E. Hood
University of Arkansas at Fayetteville
13 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
Reine U Protacio
University of Arkansas for Medical Sciences
12 shared publications
In database
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
Showing 5 of 12 shared publications
Jun Gao
University of Arkansas for Medical Sciences
11 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription
- Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast
- Phosphorylation-Independent Regulation of Atf1-Promoted Meiotic Recombination by Stress-Activated, p38 Kinase Spc1 of Fission Yeast
Showing 5 of 11 shared publications
Gregory A. Barrett-Wilt
University of Wisconsin System (US)
10 shared publications
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 10 shared publications
Venkata R. Krishnamurthi
University of Arkansas at Fayetteville
10 shared publications
In database
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 10 shared publications
Y Wang
University of Arkansas at Fayetteville
10 shared publications
In database
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 10 shared publications
A. Tackett
University of Arkansas for Medical Sciences
10 shared publications
In database
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 10 shared publications
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