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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-20
Wayne P. Wahls
Federal Grant PI
High Impact
Professor
Also affiliated: Illinois College (1990); Vanderbilt University (1997–1999); University of Arkansas Medical Center (2008–2024); University of Illinois Chicago (1990–1991); University of Chicago (1990–1991); Fred Hutch Cancer Center (1993–1997); Laboratoire de Biochimie (1998); Arkansas Department of Agriculture (2014)
Faculty Researcher
Biochemistry & Molecular Biology, College of Medicine
26 h-index
84 pubs
2,243 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Wayne P. Wahls, Professor in Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences, investigates the molecular mechanisms that govern genetic recombination, particularly during meiosis. His research group studies how environmental factors and specific DNA sequences influence the landscape of meiotic recombination, exploring its implications for evolution and genome stability. Wahls has received funding from the National Institute of General Medical Sciences for his work on elucidating DNA sequence codes that regulate meiotic recombination.
His recent publications examine the adaptive control of meiotic recombination hotspots, the function of the Pif1 helicase in unwinding DNA structures and its role in nuclear and mitochondrial processes, and the efficiency and outcomes of CRISPR/Cas9-mediated genome editing in the yeast *Schizosaccharomyces pombe*. Wahls also studies dynamic global acetylation remodeling during yeast stress responses and practical laboratory issues, such as contaminants in growth media and variations in agar composition affecting yeast plating efficiency. His work contributes to understanding fundamental biological processes and developing molecular tools.
Metrics
- h-index: 26
- Publications: 84
- Citations: 2,243
Selected Publications
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe (2025)
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Targeted Forward Genetics: Saturating Mutational Analyses of Specific Target Loci Within the Genome (2024)
Federal Grants 1 $423,218 total
NIH
Contact PI
May 2022 - Mar 2027
Systematic elucidation of DNA sequence codes that regulate meiotic recombination
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Combinatoial CREB/ATF dimers and cellular growth control NIH Principal Investigator
- Transcription-coupled Homologous Recombination Human Frontier Science Program Principal Investigator
- Center for Molecular Interactions in Cancer (CMIC) NIH Co-Investigator
- Biochemistry of recombination in meiosis NIH Principal Investigator
- HOMOLOGUS RECOMBINATION HOTSPOTS NIH Principal Investigator
- REGULATION OF MEIOTIC DEVELOPMENT BY MTS1-MTS2 PROTEIN NIH Principal Investigator
- Molecular mechanisms of aneuploidy NIH Co-Investigator
- Wahls start up account UAMS College of Medicine Principal Investigator
Collaboration Network
Top Collaborators
Reine U Protacio
University of Arkansas for Medical Sciences
5 shared publications
In database
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
- Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles
- DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe
- Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe
Reine U. Protacio
University of Arkansas for Medical Sciences
5 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Laboratory horror stories: Poison in the agars
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
- Agar lot-specific inhibition in the plating efficiency of yeast spores and cells
- Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions
Mari K. Davidson
University of Arkansas for Medical Sciences
4 shared publications
In database
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
- Laboratory horror stories: Poison in the agars
- Agar lot-specific inhibition in the plating efficiency of yeast spores and cells
Emory G. Malone
University of Arkansas for Medical Sciences
4 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles
- Agar lot-specific inhibition in the plating efficiency of yeast spores and cells
- DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe
Rebecca E. Hardman-Kavanaugh
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Aaron J. Storey
University of Arkansas for Medical Sciences
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Tara Stuecker
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Stephanie E. Hood
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Stephanie D. Byrum
University of Arkansas for Medical Sciences
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Alan J. Tackett
University of Arkansas for Medical Sciences
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Jeffrey A. Lewis
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Jun Gao
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
John C. Marecki
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
Alicia K. Byrd
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
Kevin D. Raney
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
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