Wayne P. Wahls
Federal Grant PI
High Impact
Professor
faculty
Biochemistry & Molecular Biology, College of Medicine
25 h-index
74 pubs
2,223 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Wayne P. Wahls is a Professor in the Department of Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences. His research focuses on understanding the molecular mechanisms that regulate genetic recombination, particularly during meiosis. Wahls has received a grant from the NIH/National Institute of General Medical Sciences for $423,218 to support the systematic elucidation of DNA sequence codes that regulate meiotic recombination.
His work involves studying fungal genetics, specifically in the yeast *Schizosaccharomyces pombe*, to investigate processes such as DNA repair, gene editing with CRISPR/Cas9, and global acetylation remodeling during cellular responses like heat shock. Wahls's laboratory also examines the function of specific proteins, including helicases like Pif1, and their roles in nuclear and mitochondrial functions. His research group maintains an active lab website and collaborates with researchers at the University of Arkansas for Medical Sciences and the University of Arkansas at Fayetteville.
Wahls has authored 74 publications, with an h-index of 25 and over 2,200 citations. He is recognized as a high-impact researcher and has served as a principal investigator on federal grants.
Metrics
- h-index: 25
- Publications: 74
- Citations: 2,223
Selected Publications
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe (2025)
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Dynamic global acetylation remodeling during the yeast heat shock response (2025)
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Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024)
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Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions (2024)
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Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles (2024)
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Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
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Laboratory horror stories: Poison in the agars (2024)
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Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth (2024)
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DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe (2024)
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Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution (2022)
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Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination (2021)
Federal Grants 1 $423,218 total
NIH/National Institute of General Medical Sciences
Contact PI
May 2022 - Mar 2027
Systematic elucidation of DNA sequence codes that regulate meiotic recombination
Grants & Funding
- No FP attached UAMS College of Medicine Principal Investigator
- Combinatoial CREB/ATF dimers and cellular growth control NIH Principal Investigator
- Transcription-coupled Homologous Recombination Human Frontier Science Program Principal Investigator
- Systematic elucidation of DNA sequence codes that regulate meiotic recombination NIH Principal Investigator
- Systematic elucidation of DNA sequence codes that regulate meiotic recombination NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Center for Molecular Interactions in Cancer (CMIC) NIH Co-Investigator
- Transcription-coupled Homologous Recombination Human Frontier Science Program Principal Investigator
- Biochemistry of recombination in meiosis NIH Principal Investigator
Collaboration Network
Top Collaborators
Reine U. Protacio
University of Arkansas for Medical Sciences
6 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Laboratory horror stories: Poison in the agars
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
- Agar lot-specific inhibition in the plating efficiency of yeast spores and cells
- Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions
Showing 5 of 6 shared publications
Reine U Protacio
University of Arkansas for Medical Sciences (US)
5 shared publications
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
- Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles
- DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe
- Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe
Mari K. Davidson
University of Arkansas for Medical Sciences (US)
4 shared publications
- Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution
- Laboratory horror stories: Poison in the agars
- Agar lot-specific inhibition in the plating efficiency of yeast spores and cells
Emory G. Malone
University of Arkansas for Medical Sciences
4 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles
- Agar lot-specific inhibition in the plating efficiency of yeast spores and cells
- DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe
Rebecca E. Hardman-Kavanaugh
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Aaron J. Storey
University of Arkansas for Medical Sciences
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Tara Stuecker
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Stephanie E. Hood
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Stephanie D. Byrum
University of Arkansas for Medical Sciences
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Alan J. Tackett
University of Arkansas for Medical Sciences
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Jeffrey A. Lewis
University of Arkansas at Fayetteville
3 shared publications
In database
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Jun Gao
University of Arkansas for Medical Sciences (US)
2 shared publications
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
John C. Marecki
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
Alicia K. Byrd
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
Kevin D. Raney
University of Arkansas for Medical Sciences
2 shared publications
In database
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
Similar Researchers
Based on overlapping research topics
Emory G. Malone
University of Arkansas for Medical Sciences
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