Reine U Protacio

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Staff Scientist

UAMS

Also affiliated: Northwestern University (1996–1997); Harvard University (2002–2004)

11 h-index 25 pubs 773 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Reine U. Protacio's research focuses on understanding the molecular mechanisms that govern genetic recombination, particularly during meiosis. Her work investigates how environmental factors and specific DNA sequences influence the landscape of meiotic recombination, with implications for evolutionary processes. Protacio also studies the function of helicase enzymes, such as Pif1, examining their roles in DNA unwinding, DNA repair, and mitochondrial function. Her recent publications explore the impact of CRISPR/Cas9 gene editing efficiency in yeast and address practical laboratory challenges related to yeast cell culture. Protacio collaborates with researchers at the University of Arkansas for Medical Sciences, including Wayne P. Wahls, Emory G. Malone, and Kevin D. Raney, with whom she has co-authored multiple publications. Her scholarship metrics include an h-index of 10 and 719 total citations across 17 publications.

Metrics

h-index: 11
Publications: 25
Citations: 773

Positions

Staff Scientist publications 2013–2025

University of Arkansas for Medical Sciences Institution web page

Selected Publications

Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe (2025)

PubMed DOI OpenAlex
Targeted Forward Genetics: Saturating Mutational Analyses of Specific Target Loci Within the Genome (2024)

Methods in molecular biology DOI OpenAlex
Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024)

1 citation DOI OpenAlex
Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions (2024)

Biomolecules DOI OpenAlex
Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles (2024)

PubMed 2 citations DOI OpenAlex
Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)

Nature Communications 10 citations DOI OpenAlex
Laboratory horror stories: Poison in the agars (2024)

bioRxiv (Cold Spring Harbor Laboratory) 2 citations DOI OpenAlex
Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth (2024)

Nucleic Acids Research 2 citations DOI OpenAlex
DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe (2024)

PubMed DOI OpenAlex
Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution (2022)

Frontiers in Genetics 11 citations DOI OpenAlex
Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways (2022)

Journal of Biological Chemistry 3 citations DOI OpenAlex
Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination (2021)

Genetics 20 citations DOI OpenAlex
Molecular mechanisms for environmentally induced plasticity in the positioning of meiotic recombination at hotspots (2020)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast (2019)

G3 Genes Genomes Genetics 8 citations DOI OpenAlex
Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway (2019)

Genetics 17 citations DOI OpenAlex