Mortaza Derakhshani-Molayousefi

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

University of Arkansas

Also affiliated: Southern Illinois University Edwardsville (2015–2016); Colorado State University (2020)

Faculty Researcher

5 h-index 18 pubs 80 cited

Research Areas

Biomedical Subjects

Links

Lab Website

OverviewAI-generated summary

Mortaza Derakhshani-Molayousefi's research focuses on molecular dynamics simulations to investigate the behavior and conformational changes of biological molecules and systems. His work has explored the structure and dynamics of lipid bilayers, particularly the influence of cholesterol on their properties, and the conformational dynamics of metabotropic glutamate receptor 1. He also studies the behavior of amorphous shapes, such as reverse micelles, using computational methods. Recent publications indicate a strong interest in the molecular mechanisms of drug transport, specifically focusing on multidrug resistance protein 1 (P-glycoprotein) and its modulation by lipids and nucleotides. His research aims to provide insights into drug delivery systems, such as liposomes, and to elucidate molecular interactions relevant to disease mechanisms, including quorum sensing inhibition in bacteria. He has a h-index of 5 with 17 publications and 79 citations, and collaborates with several researchers at the University of Arkansas at Fayetteville.

Metrics

h-index: 5
Publications: 18
Citations: 80

Selected Publications

Interplay Between Cholesterol Concentration and Membrane Curvature in Liposomes Revealed by Molecular Dynamics Simulations (2026)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
BPS2025 - Exploring lipid-protein interactions and nucleotide binding in multidrug resistance protein 1: Insights from molecular dynamics and free energy perturbation simulations (2025)

Biophysical Journal DOI OpenAlex
BPS2025 - Optimizing liposomal drug delivery systems through cholesterol dynamics: Insights from coarse-grained simulations (2025)

Biophysical Journal DOI OpenAlex
Shape of AOT Reverse Micelles: The Mesoscopic Assembly Is More Than the Sum of the Parts (2024)

The Journal of Physical Chemistry B 7 citations DOI OpenAlex
Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1 (2024)

bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
The effect of cholesterol concentration on planar and spherical lipid bilayers (2024)

Biophysical Journal 1 citation DOI OpenAlex
Structural effects of ALS-associated mutations on profilin (2023)

Biophysical Journal DOI OpenAlex
Cholesterol dependence on the conformational changes of metabotropic glutamate receptor 1 (mGLuR1) (2023)

Biophysical Journal DOI OpenAlex
How to Characterize Amorphous Shapes: The Tale of a Reverse Micelle (2022)

The Journal of Physical Chemistry B 10 citations DOI OpenAlex
Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein (2022)

Biophysical Journal DOI OpenAlex
Structural dynamics of prefusion spike protein of SARS-CoV-2 and its variants (2022)

Biophysical Journal DOI OpenAlex
How to Characterize Amorphous Shapes: The Tale of a Reverse Micelle (2021)

ChemRxiv DOI OpenAlex
How to Characterize Amorphous Shapes: The Tale of a Reverse Micelle (2021)

DOI OpenAlex