Match tier Confirmed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Shadi A. Badiee

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

Faculty Researcher

4 h-index 17 pubs 64 cited

  • Molecular Dynamics Simulation
  • Humans
  • Protein Conformation
  • Hemagglutinin Glycoproteins, Influenza Virus
  • Lipid Bilayers
  • Membrane Transport Proteins
  • Heparin
  • Fibroblast Growth Factor 1
  • Hydrogen Bonding
  • Hydrogen-Ion Concentration
  • Protein Domains
  • Escherichia coli
  • Gram-Negative Bacteria
  • Escherichia coli Proteins
  • Binding Sites

Biography and Research Information

OverviewAI-generated summary

Shadi A. Badiee's research program investigates the molecular mechanisms underlying biological processes, with a particular focus on protein structure, function, and dynamics. Utilizing computational approaches such as molecular dynamics simulations, Badiee studies the conformational changes of proteins, including those involved in viral infection and cellular transport. Recent work has explored the role of cholesterol in the function of Class C G protein-coupled receptors and the alternating access mechanism of multidrug resistance transporters. Badiee also investigates the structural dynamics of viral glycoproteins, such as the hemagglutinin of the influenza virus, and the complex interactions within bacterial membrane proteins. Collaborations with other researchers at the University of Arkansas at Fayetteville have resulted in shared publications examining these and related topics.

Metrics

  • h-index: 4
  • Publications: 17
  • Citations: 64

Selected Publications

  • Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1 (2026)
    Biophysical Journal DOI OpenAlex
  • Lipid-Mediated Modulation of mGluR2 Embedded in Micelle and Bilayer Environments: Insights from Molecular Dynamics (2025)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant? (2024)
    Microorganisms 1 citation DOI OpenAlex
  • Molecular Dynamics Investigation of the Influenza Hemagglutinin Conformational Changes in Acidic pH (2024)
    The Journal of Physical Chemistry B 4 citations DOI OpenAlex
  • Deciphering the Interdomain Coupling in a Gram-Negative Bacterial Membrane Insertase (2024)
    The Journal of Physical Chemistry B 2 citations DOI OpenAlex
  • Molecular dynamics investigation of the influenza hemagglutinin conformational changes in acidic pH (2024)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Lipid-dependent conformational dynamics of bacterial ATP-binding cassette transporter Sav1866 (2024)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1 (2024)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Cholesterol-regulated conformational dynamics and stability of mGluR2 embedded in detergent micelles: Insights from molecular dynamics (2024)
    Biophysical Journal DOI OpenAlex
  • The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs (2023)
    Membranes 20 citations DOI OpenAlex
  • Cholesterol in Class C GPCRs: Role, Relevance, and Localization (2023)
    Membranes 24 citations DOI OpenAlex
  • A molecular dynamics study of the FGF1/FGF2 heterodimer in human fibroblasts (2023)
    Biophysical Journal 1 citation DOI OpenAlex
  • Cholesterol in Class C GPCRs: Role, Relevance, and Localization (2023)
    Preprints.org 6 citations DOI OpenAlex
  • Molecular dynamics investigation of the ph-dependent influenza hemagglutinin conformational change (2022)
    Biophysical Journal DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

20 Collaborators 3 Institutions 1 Country

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