Prabhash Nath Tripathi

High Impact

Postdoctoral researcher

UAMS

Also affiliated: Indian Institute of Chemical Biology (2012); University of Allahabad (2024); Shobhit University (2024–2025); Chaudhary Charan Singh University (2022–2025); Himalayan Institute of Yoga Science and Philosophy (2022); Sardar Vallabhbhai Patel University of Agriculture & Technology (2025); Institute of Engineering (2022–2025); Institute of Medical Sciences (1998–2022); Charles R. Drew University of Medicine and Science (2005); Indian Institute of Technology Indore (2018); Banaras Hindu University (1998–2022); Stanford University (2024–2025)

Postdoc Researcher

20 h-index 58 pubs 1,741 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Prabhash Nath Tripathi's research focuses on the development of potential inhibitors for acetylcholinesterase (AChE) and amyloid-beta (Aβ) aggregation, with applications in treating Alzheimer's disease. His work involves screening compounds through in vitro biochemical assays and in vivo models, complemented by computational methods using Schrodinger software. Tripathi has investigated various chemical scaffolds, including 1,3,4-oxadiazole, 2-pyridylpiperazine, N-benzylpiperidine, and ferulic acid, to identify compounds with inhibitory activity against cholinesterases, beta-secretase-1, Aβ, and oxidative stress. These rationally designed compounds undergo synthesis and evaluation through in vitro enzyme and cell-based assays, preclinical in vivo studies, and ex vivo studies using rat brains. He has also engaged in collaborative research to discover hybrid ligands for Alzheimer's disease treatment.

Prior to his current role, Tripathi gained three years of industrial experience in the synthesis of organic molecules, including carbohydrate-based molecules like nucleosides and nucleotides, and biological dyes such as fluorescent molecules. His scholarly output includes 58 publications with over 1,700 citations, contributing to his h-index of 20, and he is recognized as a highly cited researcher. Tripathi leads a research group and has collaborated with researchers such as Amit Kumar Tiwari and Sanjana Sood.

Metrics

h-index: 20
Publications: 58
Citations: 1,741

Selected Publications

Mustard seeds and curry leaves: Flavorful defenders of blood sugar (2026)

Elsevier eBooks DOI OpenAlex
A Macropinocytosis-Driven Approach for Efficient Delivery of Small- and Macromolecular Cancer Therapeutics in Cancer (Abstract ID: 227830) (2026)

Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
Abstract LB315: Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer (2026)

Cancer Research DOI OpenAlex
Exploring promising pharmaceutical candidates for antiaging (2025)

Neurobiology of Aging DOI OpenAlex
Therapeutic approaches to age related cognitive decline and neurodegenerative diseases (2025)

Neurobiology of Aging DOI OpenAlex
Mitochondrial dysfunction and aging (2025)

Neurobiology of Aging 3 citations DOI OpenAlex
Neuronal loss and synaptic dysfunction (2025)

Neurobiology of Aging DOI OpenAlex
Nutrient-Sensing Pathways: Gatekeepers of Longevity (2025)

Nutritional neurosciences 3 citations DOI OpenAlex
Intellectual Property Rights in Neuroprotective Biomaterials (2025)

39 citations DOI OpenAlex
Emerging Trends: Neurofilament Biomarkers in Precision Neurology (2024)

Neurochemical Research 29 citations DOI OpenAlex