Ravi W. Sun
Researcher
Also affiliated: Arkansas Children's Hospital (2017–2026); University of Arkansas System (2021); Siloah St. Trudpert Klinikum (2011)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Ravi W. Sun's research focuses on the cellular and molecular mechanisms underlying vascular malformations. His work investigates the hyperproliferative nature of endothelial cells in conditions such as venous malformations and arteriovenous malformations. Sun has published studies examining dysregulated signaling pathways, including TGF-β/BMP, and the role of specific microRNAs, such as microRNA-21, in driving cell proliferation and inhibiting tumor suppressor genes like PDCD4 in lymphatic malformations. His research also explores the involvement of mural cells in endothelial-to-mesenchymal transition within arteriovenous malformations and the potential therapeutic inhibition of factors like Angiopoietin-2 to control malformation cell growth. Sun collaborates with several researchers at the University of Arkansas for Medical Sciences, including Graham M. Strub and Gresham T. Richter, with whom he has co-authored multiple publications.
Metrics
- h-index: 7
- Publications: 17
- Citations: 135
Selected Publications
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M2 Macrophage Polarization Characterizes an Immunosuppressive Microenvironment in Extracranial Arteriovenous Malformations (2026)
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Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells (2025)
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Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs (2024)
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Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4 (2023)
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Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1 (2022)
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Bronchogenic cyst of the posterior neck mimicking lymphatic malformation (2022)
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Venous malformation vessels are improperly specified and hyperproliferative (2021)
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NOTCH pathway activation in infantile hemangiomas (2020)
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Eosinophilic Esophagitis (2019)
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Abnormal elastin and collagen deposition is present in extracranial arteriovenous malformations: A comparison to intracranial disease. (2019)
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A novel surgical treatment for posterior glottic stenosis using thyroid ala cartilage – A case report and literature review (2018)
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Current status, pitfalls and future directions in the diagnosis and therapy of lymphatic malformation (2017)
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Eosinophilic esophagitis in children under the age of 5 years: Clinical characteristics (2017)
Collaboration Network
Top Collaborators
- Venous malformation vessels are improperly specified and hyperproliferative
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Venous malformation vessels are improperly specified and hyperproliferative
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Venous malformation vessels are improperly specified and hyperproliferative
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Venous malformation vessels are improperly specified and hyperproliferative
- Venous malformation vessels are improperly specified and hyperproliferative
- Venous malformation vessels are improperly specified and hyperproliferative
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
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