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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Ravi W. Sun

Researcher

Also affiliated: Arkansas Children's Hospital (2017–2026); University of Arkansas System (2021); Siloah St. Trudpert Klinikum (2011)

Faculty Researcher

7 h-index 17 pubs 135 cited

  • Humans
  • Cell Proliferation
  • Endothelial Cells
  • Male
  • Arteriovenous Malformations
  • Female
  • Lymphatic Abnormalities
  • Endothelium, Vascular
  • Vascular Malformations
  • Child, Preschool
  • Retrospective Studies
  • Infant
  • Neovascularization, Pathologic
  • Signal Transduction
  • Transforming Growth Factor beta1

Biography and Research Information

OverviewAI-generated summary

Ravi W. Sun's research focuses on the cellular and molecular mechanisms underlying vascular malformations. His work investigates the hyperproliferative nature of endothelial cells in conditions such as venous malformations and arteriovenous malformations. Sun has published studies examining dysregulated signaling pathways, including TGF-β/BMP, and the role of specific microRNAs, such as microRNA-21, in driving cell proliferation and inhibiting tumor suppressor genes like PDCD4 in lymphatic malformations. His research also explores the involvement of mural cells in endothelial-to-mesenchymal transition within arteriovenous malformations and the potential therapeutic inhibition of factors like Angiopoietin-2 to control malformation cell growth. Sun collaborates with several researchers at the University of Arkansas for Medical Sciences, including Graham M. Strub and Gresham T. Richter, with whom he has co-authored multiple publications.

Metrics

  • h-index: 7
  • Publications: 17
  • Citations: 135

Selected Publications

  • M2 Macrophage Polarization Characterizes an Immunosuppressive Microenvironment in Extracranial Arteriovenous Malformations (2026)
    Biomedicines DOI OpenAlex
  • Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells (2025)
    The FASEB Journal 1 citation DOI OpenAlex
  • Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs (2024)
    Cells 2 citations DOI OpenAlex
  • Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4 (2023)
    Journal of Investigative Dermatology 6 citations DOI OpenAlex
  • Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1 (2022)
    Scientific Reports 10 citations DOI OpenAlex
  • Bronchogenic cyst of the posterior neck mimicking lymphatic malformation (2022)
    Clinical Case Reports 3 citations DOI OpenAlex
  • Venous malformation vessels are improperly specified and hyperproliferative (2021)
    PLoS ONE 16 citations DOI OpenAlex
  • NOTCH pathway activation in infantile hemangiomas (2020)
    Journal of Vascular Surgery Venous and Lymphatic Disorders 15 citations DOI OpenAlex
  • Eosinophilic Esophagitis (2019)
    2 citations DOI OpenAlex
  • Abnormal elastin and collagen deposition is present in extracranial arteriovenous malformations: A comparison to intracranial disease. (2019)
    PubMed 11 citations DOI OpenAlex
  • A novel surgical treatment for posterior glottic stenosis using thyroid ala cartilage – A case report and literature review (2018)
    International Journal of Pediatric Otorhinolaryngology 8 citations DOI OpenAlex
  • Current status, pitfalls and future directions in the diagnosis and therapy of lymphatic malformation (2017)
    Journal of Biophotonics 45 citations DOI OpenAlex
  • Eosinophilic esophagitis in children under the age of 5 years: Clinical characteristics (2017)
    The Laryngoscope 15 citations DOI OpenAlex

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Collaboration Network

27 Collaborators 5 Institutions 1 Country

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