Graham M. Strub
Associate Professor
Also affiliated: Boston Children's Hospital (2018); Arkansas Children's Hospital (2020–2026); Harvard University (2018); University of Richmond (2001); Virginia Commonwealth University (2009–2010); University of Washington (2011–2018); University of Arkansas Medical Center (2020–2023); University of Arkansas System (2021–2026); Arkansas Children's Nutrition Center (2020–2022); Virginia Commonwealth University Medical Center (2008–2012); Marshall University (2010)
Faculty Researcher
Otolaryngology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Graham M. Strub's research focuses on vascular anomalies, particularly arteriovenous malformations (AVMs) and lymphatic malformations (LMs). His work investigates the molecular mechanisms driving the proliferation of endothelial cells in these conditions, exploring signaling pathways such as TGF-β/BMP and the role of microRNAs like miR-21. Strub has also examined quantitative plasma proteomic analyses in children following surgical procedures related to pulmonary arteriovenous malformations. His publications include studies on the dysregulation of signaling pathways in extracranial AVMs, the initiation of endothelial-to-mesenchymal transition by mural cells in AVMs, and the use of microRNAs to inhibit cell proliferation in LMs. Additionally, Strub has contributed to practice pattern studies for genetic testing in vascular anomalies and has an interest in improving diversity in medical residency interviews. His scholarship metrics include an h-index of 10 with over 3,200 citations across 41 publications.
Metrics
- h-index: 10
- Publications: 42
- Citations: 3,298
Selected Publications
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M2 Macrophage Polarization Characterizes an Immunosuppressive Microenvironment in Extracranial Arteriovenous Malformations (2026)
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A Case of Noncommunicating Hydrocephalus Presenting as Isolated Hyposmia (2026)
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Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells (2025)
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Toward an Unbiased Deep Learning Classifier of Pediatric Middle Ear Disease (2025)
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Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs (2024)
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Advanced laryngeal squamous cell carcinoma in an adolescent: A case and treatment considerations (2024)
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Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations (2024)
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Massive Subcutaneous Emphysema after Hydrogen Peroxide Irrigation of a Penetrating Facial Injury (2023)
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Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4 (2023)
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Genetic testing for vascular anomalies – American society of pediatric otolaryngology vascular anomalies task force practice patterns (2022)
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Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1 (2022)
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A novel algorithm to reduce bias and improve the quality and diversity of residency interviewees (2022)
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Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1 (2022)
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Bronchogenic cyst of the posterior neck mimicking lymphatic malformation (2022)
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Detection of Respiratory Pathogens Does Not Predict Risks After Outpatient Adenotonsillectomy (2020)
Grants & Funding
As listed on this researcher's institutional profile.
- Next Generation Treatments for Lymphatic Malformations NIH Principal Investigator
- AWD-034171: 4517 - CTPR Phase II - Admin Core 07/01/2022 (version 0) Grant: GR034175 4687 Tackett COBRE CTPR Phase II - Project 5 Strub UAMS ACHRI Flow Through Principal Investigator
- Intracellular Target of Sphingosine-1-Phosphate NIH Principal Investigator
Collaboration Network
Top Collaborators
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
Showing 5 of 7 shared publications
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
Showing 5 of 6 shared publications
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- A novel algorithm to reduce bias and improve the quality and diversity of residency interviewees
- Toward an Unbiased Deep Learning Classifier of Pediatric Middle Ear Disease
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
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