Rushita Adhikari Bagchi

High Impact

Assistant Professor

UAMS

Also affiliated: University of Burdwan (2015); St. Boniface Hospital (2012–2018); University of Manitoba (2011–2018); University of Colorado Anschutz (2013–2024); University of Colorado Denver (2013–2021)

26 h-index 98 pubs 1,826 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group UAMS TRI Profile

OverviewAI-generated summary

Rushita Adhikari Bagchi's research focuses on the molecular mechanisms underlying cardiovascular and metabolic diseases, particularly investigating the role of histone deacetylases (HDACs) and chromatin remodeling in these conditions.

Her work has explored how dynamic chromatin targeting, specifically involving BRD4, contributes to cardiac fibroblast activation. She has also investigated the therapeutic potential of HDAC inhibition, demonstrating its ability to reverse diastolic dysfunction and modulate extracellular matrix remodeling. Further research has examined the suppression of thermogenic programs in adipose tissue by HDAC11 and the restoration of leptin sensitivity through HDAC6 inhibition in obesity models. Her publications also include studies on oxidative stress and altered energy production in the heart following ischemic acute kidney injury in mice, and the regulation of cardiac fibroblast phenotype by the transcription factor scleraxis.

Bagchi holds a high-impact researcher designation and has an h-index of 26 with 99 total publications and 1,822 total citations. She leads a research group and collaborates with several colleagues at the University of Arkansas for Medical Sciences, including S Ibrahim, Ryan Holdiness, Ashim K. Bagchi, and Se‐Ran Jun.

Metrics

h-index: 26
Publications: 98
Citations: 1,826

Positions

Assistant Professor 2024–present

University of Arkansas for Medical Sciences Physiology and Cell Biology Institutional directory
Postdoctoral Fellow 2015–2022

University of Colorado - Anschutz Medical Campus Medicine-Cardiology ORCID

Selected Publications

Cardiac Fibroblasts in Extracellular Matrix Homeostasis and Remodeling (2026)

American Journal of Physiology-Heart and Circulatory Physiology DOI OpenAlex
Uncovering a novel cell death-independent mechanism of acute anthracycline toxicity in human cardiac fibroblasts (2026)

Physiology DOI OpenAlex
Sex-Specific Adipose Transcriptomic Reprogramming Drives Early Inter-Organ Remodeling in Heart and Liver Under Nutrient Excess (2026)

Physiology DOI OpenAlex
Hidden Receptor Crosstalk Governs Lymphatic Failure After Cancer Therapy (2026)

The FASEB Journal DOI OpenAlex
A call to redefine cardiovascular immunobiology around leukocyte plasticity (2026)

American Journal of Physiology-Heart and Circulatory Physiology DOI OpenAlex
A Defined and Cost-Efficient Strategy for Generating Functionally Quiescent Human iPSC-Derived Cardiac Fibroblasts (2026)

Research Square DOI OpenAlex
3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease (2025)

American Journal of Physiology-Heart and Circulatory Physiology 1 citation DOI OpenAlex
Temporal Dynamics of Extracellular Matrix Remodeling in Anthracycline-Induced Cardiotoxicity (2025)

Cells 5 citations DOI OpenAlex
Interplay between stress, chloride homeostasis, and cardiovascular regulation (2025)

American Journal of Physiology-Heart and Circulatory Physiology DOI OpenAlex
Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress (2025)

Physiology DOI OpenAlex
Global Transcriptional Profiling of Adipose Tissue Uncovers Unique Sex-Dependent Mechanisms in Acute Obesity: Implications for Adipose-Heart Interorgan Crosstalk (2025)

Physiology DOI OpenAlex
Obesity, histone acetylation, and insulin resistance (2024)

Elsevier eBooks DOI OpenAlex
List of contributors (2024)

Elsevier eBooks DOI OpenAlex
Histone Deacetylases in Metabolism: the Known and the Unexplored (2024)

Physiology 8 citations DOI OpenAlex
Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts (2024)

Physiology DOI OpenAlex

View all publications on OpenAlex →

Grants & Funding

As listed on this researcher's institutional profile.

Research Training Award American Physiological Society
Mapping the interactome of a lysine demyristoylase in the diabetic heart Brunson Endowment Grant for Cardiovascular Diseases Research/UAMS College of Medicine
Elucidation of the regulatory role of scleraxis in cardiac fibrosis (Funded by: Canadian Institutes of Health Research (CIHR)/Research Manitoba Predoctoral Research Award)
HDAC11 in Diabetic Cardiomyopathy American Heart Association Career Development Award
ABI P. Prather NIH T32 FY26 Y3 State of Arkansas
A Multi-omics Approach to Identify Mechanisms of HDAC11 mediated Lipid Regulation in the Diabetic Heart Sturgis Endowment Grant for Diabetes Research/UAMS College of Medicine
Epigenetic regulation of cardiac hypertrophy by BET acetyl-lysine binding proteins (Funded by: Canadian Institutes of Health Research (CIHR) Postdoctoral Research Fellowship)