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Biography and Research Information
OverviewAI-generated summary
Ashim K. Bagchi's research focuses on the molecular mechanisms underlying cardiovascular diseases, particularly those induced by chemotherapy agents like doxorubicin. His work investigates the roles of oxidative stress, endoplasmic reticulum (ER) stress, and apoptotic pathways in the development of doxorubicin-induced cardiomyopathy. Bagchi has published studies examining how factors such as Interleukin-10 and empagliflozin can mitigate these damaging effects by modulating ER stress pathways. His research also extends to other forms of heart failure, including studies on the protective effects of olive oil against cardiac remodeling following myocardial infarction in rats and the role of oxidative stress versus lipids in monocrotaline-induced pulmonary hypertension. Bagchi has a scholarly h-index of 18 with 1,290 citations across 67 publications. He has collaborated with Amanda J. Stolarz, Rushita A. Bagchi, Soumiya Pal, and Jawahar L. Mehta on multiple projects.
Metrics
- h-index: 18
- Publications: 67
- Citations: 1,290
Selected Publications
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Obesity, histone acetylation, and insulin resistance (2024)
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List of contributors (2024)
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Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats (2024)
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Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts (2024)
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JoVE Video Dataset (2024)
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Real-Time Evaluation of Absolute, Cytosolic, Free Ca<sup>2+</sup> and Corresponding Contractility in Isolated, Pressurized Lymph Vessels (2024)
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Doxorubicin‑induced cardiomyopathy is mitigated by empagliflozin via the modulation of endoplasmic reticulum stress pathways (2024)
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The cardioprotective effects of Empagliflozin in Doxorubicin-induced endoplasmic reticulum (ER) stress (2023)
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Lipidomic Predictors of Coronary No-Reflow (2023)
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Olive oil protects against progression of heart failure by inhibiting remodeling of heart subsequent to myocardial infarction in rats (2022)
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NF-κB, A Potential Therapeutic Target in Cardiovascular Diseases (2022)
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The Structural Basis of Effective LOX-1 Inhibition (2022)
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Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy (2022)
Collaboration Network
Top Collaborators
Pawan K. Singal
St. Boniface Hospital (CA)
11 shared publications
- Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin
- Endoplasmic Reticulum Stress Promotes iNOS/NO and Influences Inflammation in the Development of Doxorubicin-Induced Cardiomyopathy
- Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy
- Olive oil protects against progression of heart failure by inhibiting remodeling of heart subsequent to myocardial infarction in rats
- Role of oxidative stress versus lipids in monocrotaline‐induced pulmonary hypertension and right heart failure
Showing 5 of 11 shared publications
Akshi Malik
University of Manitoba (CA)
10 shared publications
- Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin
- Endoplasmic Reticulum Stress Promotes iNOS/NO and Influences Inflammation in the Development of Doxorubicin-Induced Cardiomyopathy
- Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy
- Olive oil protects against progression of heart failure by inhibiting remodeling of heart subsequent to myocardial infarction in rats
- Role of oxidative stress versus lipids in monocrotaline‐induced pulmonary hypertension and right heart failure
Showing 5 of 10 shared publications
Davinder S. Jassal
University of Manitoba (CA)
7 shared publications
- Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin
- Endoplasmic Reticulum Stress Promotes iNOS/NO and Influences Inflammation in the Development of Doxorubicin-Induced Cardiomyopathy
- Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy
- Olive oil protects against progression of heart failure by inhibiting remodeling of heart subsequent to myocardial infarction in rats
- Doxorubicin‑induced cardiomyopathy is mitigated by empagliflozin via the modulation of endoplasmic reticulum stress pathways
Showing 5 of 7 shared publications
Gauri Akolkar
University of Ottawa (CA)
4 shared publications
- Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin
- Endoplasmic Reticulum Stress Promotes iNOS/NO and Influences Inflammation in the Development of Doxorubicin-Induced Cardiomyopathy
- IL-10: A Key Molecule in the Mitigation of Heart Failure
- Role of Nitric Oxide Synthases in Doxorubicin-Induced Cardiomyopathy
Amanda J. Stolarz
University of Arkansas for Medical Sciences
4 shared publications
In database
- Real-Time Evaluation of Absolute, Cytosolic, Free Ca<sup>2+</sup> and Corresponding Contractility in Isolated, Pressurized Lymph Vessels
- JoVE Video Dataset
- Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts
- Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats
Soumiya Pal
University of Arkansas for Medical Sciences
3 shared publications
In database
- Real-Time Evaluation of Absolute, Cytosolic, Free Ca<sup>2+</sup> and Corresponding Contractility in Isolated, Pressurized Lymph Vessels
- JoVE Video Dataset
- Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats
Anya Dhar
University of Michigan–Ann Arbor (US)
3 shared publications
- Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts
- List of contributors
- Obesity, histone acetylation, and insulin resistance
Rushita A. Bagchi
University of Arkansas for Medical Sciences
3 shared publications
In database
- Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts
- List of contributors
- Obesity, histone acetylation, and insulin resistance
Adriane Belló‐Klein
Universidade Federal do Rio Grande do Sul (BR)
2 shared publications
- Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin
- IL-10: A Key Molecule in the Mitigation of Heart Failure
Arun Surendran
University of Manitoba (CA)
2 shared publications
- Lipidomic Predictors of Coronary No-Reflow
- PLASMA LIPIDOMICS IN PATIENTS WITH CORONARY NO REFLOW
Umar Ismail
University of Manitoba (CA)
2 shared publications
- Lipidomic Predictors of Coronary No-Reflow
- PLASMA LIPIDOMICS IN PATIENTS WITH CORONARY NO REFLOW
Negar Atefi
St. Boniface Hospital (CA)
2 shared publications
- Lipidomic Predictors of Coronary No-Reflow
- PLASMA LIPIDOMICS IN PATIENTS WITH CORONARY NO REFLOW
Michel Aliani
University of Manitoba (CA)
2 shared publications
- Lipidomic Predictors of Coronary No-Reflow
- PLASMA LIPIDOMICS IN PATIENTS WITH CORONARY NO REFLOW
Jawahar L. Mehta
Central Arkansas Veterans Healthcare System
2 shared publications
In database
- NF-κB, A Potential Therapeutic Target in Cardiovascular Diseases
- The Structural Basis of Effective LOX-1 Inhibition
Neelam Khaper
NOSM University (CA)
2 shared publications
- IL-10: A Key Molecule in the Mitigation of Heart Failure
- Role of Nitric Oxide Synthases in Doxorubicin-Induced Cardiomyopathy
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