S
Samaneh Goorani
Assistant Research Professor
faculty
COP | Pharmaceutical Science
14 h-index
61 pubs
1,045 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Samaneh Goorani's research investigates the physiological impacts of environmental factors and medical conditions, with a particular focus on hypertension and the effects of microplastics. Her work includes studies on salt-sensitive hypertension following unilateral ureteral obstruction in animal models, and the reproductive toxicity of polystyrene microplastics in male mice. Goorani also explores the potential therapeutic applications of nanoparticles, investigating the antioxidant and cytotoxic properties of copper and tin nanoparticles synthesized using medicinal plants, as well as silver/chitosan nanoparticles for heart failure treatment in rats. She has published extensively on these topics, with a h-index of 14 and over 1,000 citations. Her collaborations at the University of Arkansas for Medical Sciences include extensive work with John D. Imig, Abdul H. Khan, Abhishek Mishra, and Henry A. Palfrey.
Metrics
- h-index: 14
- Publications: 61
- Citations: 1,045
Selected Publications
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Renal Hemodynamics Underlie Hepatorenal Physiology in Bile Duct-Ligated Rats (2026)
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EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage (2025)
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Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice (2025)
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Targeting p66Shc to restore KATP channel and renal microvascular responses in a preclinical model of diabetic nephropathy (2025)
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Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice (2025)
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Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol (2025)
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591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice (2025)
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Editorial: Debates in experimental pharmacology and drug discovery 2023: innovative approaches to chronic kidney disease drug discovery, identification of targets and safety assessment (2025)
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Hypertension: A Continuing Public Healthcare Issue (2024)
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The Immune System in Nephrotoxicity (2024)
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Polystyrene microplastics cause reproductive toxicity in male mice (2024)
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Kidney Hypoplasia Increases Kidney Injury following Reversal of Unilateral Ureteral Obstruction (2024)
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Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4 (2024)
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Novel compounds that target epoxyeicosanoids protect rat kidney epithelial cells in organ transplant solution during cold storage (2024)
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557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis. (2024)
Collaboration Network
Top Collaborators
John D. Imig
University of Arkansas for Medical Sciences
17 shared publications
In database
- Hypertension: A Continuing Public Healthcare Issue
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences
- <scp>Multi‐target</scp> Drugs to Treat Metabolic Diseases
- Lack of Kidney Injury Sex Differences in Unilateral Ureter Obstructed Mice
Showing 5 of 17 shared publications
Hassan Morovvati
University of Tehran (IR)
10 shared publications
- Novel green formulation of copper nanoparticles by Foeniculum vulgare: Chemical characterization and determination of cytotoxicity, anti-human lung cancer and antioxidant effects
- Polystyrene microplastics cause reproductive toxicity in male mice
- Biosynthesis of copper oxide nanoparticles (CuO NPs) using sodium lignosulfonate and evaluation of its cutaneous wound healing properties
- Novel formulation, characterization, cytotoxicity, antioxidant, and anti-lung cancer activities of silver nanoparticles green-formulated by plant extract
- Green synthesis, characterization and anti-atherosclerotic properties of vanadium nanoparticles
Showing 5 of 10 shared publications
Abdul H. Khan
University of Arkansas for Medical Sciences
8 shared publications
In database
- Polystyrene microplastics cause reproductive toxicity in male mice
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences
- Editorial: Debates in experimental pharmacology and drug discovery 2023: innovative approaches to chronic kidney disease drug discovery, identification of targets and safety assessment
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
Showing 5 of 8 shared publications
Abhishek Mishra
University of Arkansas for Medical Sciences
5 shared publications
In database
- Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences
- The Immune System in Nephrotoxicity
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
- EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage
Henry A. Palfrey
University of Arkansas for Medical Sciences
4 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Somaye Zangene
University of Tehran (IR)
4 shared publications
- Hypertension: A Continuing Public Healthcare Issue
- Polystyrene microplastics cause reproductive toxicity in male mice
- Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol
- Effects of Polystyrene Microplastics on Mice Cardiac Tissue Structure: Protective Role of Resveratrol
Behnam Mahdavi
Hakim Sabzevari University (IR)
3 shared publications
- Novel green synthesis of tin nanoparticles by medicinal plant: Chemical characterization and determination of cytotoxicity, cutaneous wound healing and antioxidant properties
- Gold nanoparticles formulated with Nigella aqueous extract having potent antioxidant and anti-human ovarian cancer activities in vitro condition
- Anti-breast carcinoma effects of green synthesized nickel nanoparticles from Alhagi sparsifolia leaf aqueous extract: A pre-clinical trial study
Ashraf El‐Meanawy
Medical College of Wisconsin (US)
3 shared publications
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences
- Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
Baku Acharya
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Brendan Frett
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Hojat Anbara
University of Tehran (IR)
3 shared publications
- Polystyrene microplastics cause reproductive toxicity in male mice
- Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol
- Effects of Polystyrene Microplastics on Mice Cardiac Tissue Structure: Protective Role of Resveratrol
Khodabakhsh Rashidi
Kermanshah University of Medical Sciences (IR)
2 shared publications
- Gold nanoparticles formulated with Nigella aqueous extract having potent antioxidant and anti-human ovarian cancer activities in vitro condition
- Anti-breast carcinoma effects of green synthesized nickel nanoparticles from Alhagi sparsifolia leaf aqueous extract: A pre-clinical trial study
Ali Aidy
Medical University of Ilam (IR)
2 shared publications
- Anti-human lung adenocarcinoma, cytotoxicity, and antioxidant potentials of copper nanoparticles green-synthesized by <i>Calendula officinalis</i>
- Gold nanoparticles formulated with Nigella aqueous extract having potent antioxidant and anti-human ovarian cancer activities in vitro condition
Akram Zangeneh
Ilam University (IR)
2 shared publications
- Biosynthesis of copper oxide nanoparticles (CuO NPs) using sodium lignosulfonate and evaluation of its cutaneous wound healing properties
- Gold nanoparticles formulated with Nigella aqueous extract having potent antioxidant and anti-human ovarian cancer activities in vitro condition
Mohammad Mahdi Zangeneh
Ilam University (IR)
2 shared publications
- Biosynthesis of copper oxide nanoparticles (CuO NPs) using sodium lignosulfonate and evaluation of its cutaneous wound healing properties
- Anti-breast carcinoma effects of green synthesized nickel nanoparticles from Alhagi sparsifolia leaf aqueous extract: A pre-clinical trial study
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