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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
S
Samaneh Goorani
Assistant Research Professor
Also affiliated: Medical College of Wisconsin (2023–2025); University of Tehran (2018–2024); University of Arkansas Medical Center (2024–2025); Islamic Azad University Pharmaceutical Sciences Branch (2014)
Faculty Researcher
COP | Pharmaceutical Science
14 h-index
61 pubs
1,107 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Samaneh Goorani's research investigates the multifaceted roles of nanoparticles in biological systems and the physiological impacts of environmental contaminants. Her work includes the green synthesis of copper, tin, and silver/chitosan nanoparticles, examining their chemical characterization and evaluating their cytotoxicity, antioxidant properties, and potential in wound healing and managing conditions like heart failure. Goorani also studies the health consequences of microplastic exposure, specifically focusing on reproductive toxicity in male mice. Her research extends to understanding disease mechanisms, such as salt-sensitive hypertension following ureteral obstruction, and exploring therapeutic strategies like multi-target drugs for metabolic diseases. She has published extensively on these topics and collaborates with researchers at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 14
- Publications: 61
- Citations: 1,107
Selected Publications
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Sorafenib Treatment Results in Greater Kidney Injury in Renal Hypoplasia Mice (Abstract ID: 272359) (2026)
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Renal hemodynamics underlie hepatorenal physiology in bile duct-ligated rats (2026)
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EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage (2025)
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Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice (2025)
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Targeting p66Shc to restore KATP channel and renal microvascular responses in a preclinical model of diabetic nephropathy (2025)
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Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice (2025)
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Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol (2025)
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591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice (2025)
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Editorial: Debates in experimental pharmacology and drug discovery 2023: innovative approaches to chronic kidney disease drug discovery, identification of targets and safety assessment (2025)
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Hypertension: A Continuing Public Healthcare Issue (2024)
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The Immune System in Nephrotoxicity (2024)
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Polystyrene microplastics cause reproductive toxicity in male mice (2024)
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Kidney Hypoplasia Increases Kidney Injury following Reversal of Unilateral Ureteral Obstruction (2024)
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Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4 (2024)
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Novel compounds that target epoxyeicosanoids protect rat kidney epithelial cells in organ transplant solution during cold storage (2024)
Collaboration Network
Top Collaborators
John D. Imig
University of Arkansas for Medical Sciences
14 shared publications
In database
- Hypertension: A Continuing Public Healthcare Issue
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Lack of Kidney Injury Sex Differences in Unilateral Ureter Obstructed Mice
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Novel compounds that target epoxyeicosanoids protect rat kidney epithelial cells in organ transplant solution during cold storage
Showing 5 of 14 shared publications
Abdul H. Khan
University of Arkansas for Medical Sciences
7 shared publications
In database
- Polystyrene microplastics cause reproductive toxicity in male mice
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Editorial: Debates in experimental pharmacology and drug discovery 2023: innovative approaches to chronic kidney disease drug discovery, identification of targets and safety assessment
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Showing 5 of 7 shared publications
Henry A. Palfrey
University of Arkansas for Medical Sciences
4 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Abhishek Mishra
University of Arkansas for Medical Sciences
4 shared publications
In database
- The Immune System in Nephrotoxicity
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
- EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage
Baku Acharya
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Brendan Frett
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Somaye Zangene
University of Tehran (IR)
3 shared publications
- Hypertension: A Continuing Public Healthcare Issue
- Polystyrene microplastics cause reproductive toxicity in male mice
- Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol
Wojciech K. Jankiewicz
Medical College of Wisconsin (US)
2 shared publications
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
Michael M. Yeboah
Medical College of Wisconsin (US)
2 shared publications
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
Ashraf El‐Meanawy
Medical College of Wisconsin (US)
2 shared publications
- Salt-sensitive hypertension after reversal of unilateral ureteral obstruction
- Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
Amod Sharma
University of Arkansas for Medical Sciences
2 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
John R. Falck
The University of Texas Southwestern Medical Center (US)
2 shared publications
- Novel compounds that target epoxyeicosanoids protect rat kidney epithelial cells in organ transplant solution during cold storage
- Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
Bruce D. Hammock
UC Davis Comprehensive Cancer Center
2 shared publications
- Novel compounds that target epoxyeicosanoids protect rat kidney epithelial cells in organ transplant solution during cold storage
- Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
Hassan Morovvati
University of Tehran (IR)
2 shared publications
- Polystyrene microplastics cause reproductive toxicity in male mice
- Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol
Hojat Anbara
University of Tehran (IR)
2 shared publications
- Polystyrene microplastics cause reproductive toxicity in male mice
- Effects of polystyrene microplastics on mice cardiac tissue structure: Protective role of resveratrol
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