Biography and Research Information
OverviewAI-generated summary
Henry A. Palfrey is a postdoctoral fellow at the University of Arkansas for Medical Sciences. His research focuses on the role of eicosanoids in kidney and cardiovascular function, with specific attention to radiation-induced kidney injury and potential pharmacotherapeutic interventions. Palfrey also collaborates with engineers on the development and commercialization of a novel medical device, stemming from a research commercialization fellowship. His previous work includes studies on the prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in rats and the adverse cardiac events associated with hypercholesterolemia and sitagliptin administration in Sprague Dawley rats. He has also investigated the therapeutic potential of dual TGFβR1/MAP4K4 inhibitors in reducing renal fibrosis and injury in mouse models.
Metrics
- h-index: 3
- Publications: 10
- Citations: 403
Selected Publications
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Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice (2025)
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591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice (2025)
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Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4 (2024)
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557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis. (2024)
Collaboration Network
Top Collaborators
Samaneh Goorani
University of Arkansas for Medical Sciences
4 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
John D. Imig
4 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Rashmi Pathak
Southern University and Agricultural and Mechanical College (US)
3 shared publications
- Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet
- Adverse cardiac events of hypercholesterolemia are enhanced by sitagliptin in sprague dawley rats
- Adverse Cardiac Events of Hypercholesterolemia Are Enhanced by Sitagliptin Administration in Sprague Dawley Rats
Avinash Kumar
Southern University and Agricultural and Mechanical College (US)
3 shared publications
- Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet
- Adverse cardiac events of hypercholesterolemia are enhanced by sitagliptin in sprague dawley rats
- Adverse Cardiac Events of Hypercholesterolemia Are Enhanced by Sitagliptin Administration in Sprague Dawley Rats
Kirsten P. Stone
Pennington Biomedical Research Center (US)
3 shared publications
- Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet
- Adverse cardiac events of hypercholesterolemia are enhanced by sitagliptin in sprague dawley rats
- Adverse Cardiac Events of Hypercholesterolemia Are Enhanced by Sitagliptin Administration in Sprague Dawley Rats
Thomas W. Gettys
Pennington Biomedical Research Center (US)
3 shared publications
- Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet
- Adverse cardiac events of hypercholesterolemia are enhanced by sitagliptin in sprague dawley rats
- Adverse Cardiac Events of Hypercholesterolemia Are Enhanced by Sitagliptin Administration in Sprague Dawley Rats
Subramanyam N. Murthy
Southern University and Agricultural and Mechanical College (US)
3 shared publications
- Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet
- Adverse cardiac events of hypercholesterolemia are enhanced by sitagliptin in sprague dawley rats
- Adverse Cardiac Events of Hypercholesterolemia Are Enhanced by Sitagliptin Administration in Sprague Dawley Rats
Baku Acharya
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Brendan Frett
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Amod Sharma
University of Arkansas for Medical Sciences (US)
2 shared publications
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
Abhishek Mishra
University of Arkansas for Medical Sciences
2 shared publications
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Abdul H. Khan
University of Arkansas for Medical Sciences
2 shared publications
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Narayan R. Raju
1 shared publication
- Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague–Dawley rats fed a high-cholesterol diet
Mohani Abdul
University of Arkansas for Medical Sciences
1 shared publication
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
Rupak Pathak
University of Arkansas for Medical Sciences
1 shared publication
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
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