Sara C. Shalin
Professor
Also affiliated: Brigham and Women's Hospital (2024); Harvard University (2024); Medical University of South Carolina (2020); Baylor College of Medicine (2004–2022); University of Arkansas Medical Center (2014–2026); University of Mississippi Medical Center (2019); Arlington Dermatology (2019); Dermatrials Research (2019); University of South Alabama Medical Center (2024); Gabba Dermatology (2019); Saint Louis University (2019); University of South Alabama (2024)
Department Chairs, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Sara C. Shalin's research focuses on cancer, particularly melanoma, and the underlying molecular mechanisms driving its progression and metastasis. She has investigated the role of specific proteins, such as E-Cadherin and EZH2 histone methyltransferase, in melanoma development and responsiveness to immune checkpoint inhibitors. Her work also extends to the study of sebaceous neoplasia and its connection to Muir-Torre syndrome, highlighting important clinical implications.
In addition to her work on cancer, Shalin has contributed to the understanding of neuronal signaling pathways involved in synaptic plasticity, memory formation, and fear conditioning in mice. Her research group at the University of Arkansas for Medical Sciences includes collaborators such as Megan S. Evans, Brian Koss, Ricky D. Edmondson, and Kirk L. West. Shalin is a highly cited researcher with an h-index of 21 and over 2,460 citations across her 153 publications. She has also served as Co-PI on the NIH-funded Clinician Research Education and Scientific Training (CREST) Program, which received $269,148.
Metrics
- h-index: 21
- Publications: 151
- Citations: 2,467
Positions
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Professor 2022–presentUniversity of Arkansas for Medical Sciences Department Chairs, College of Medicine Institutional directory
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Associate Professor 2017–2022University of Arkansas for Medical Sciences Pathology and Dermatology ORCID
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Assistant Professor 2012–2017University of Arkansas for Medical Sciences Pathology and Dermatology ORCID
Selected Publications
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Lupus Miliaris Disseminatus Faciei and Follicular Mucinosis: A New Pattern of Janus Kinase Inhibitor Acneiform Eruption (2026)
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Incise parallel, section perpendicular to the dermatoglyphs for diagnosis of acral melanocytic lesions—A comment on Thakker et al (2026)
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Photo Quiz: Persistent eyelash debris in a 10-year-old female (2026)
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Clinical Outcomes and Prognostication of CRTC1::TRIM11 Fusion Cutaneous Tumors (2026)
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Hypertrophic Lichen Sclerosus (2026)
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A 25-year evolution of systemic mastocytosis to mast cell leukemia: Cutaneous clues (2026)
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Case Study of Fulminant Pyoderma Gangrenosum: Conservative Therapy―Cornerstone of Management (2026)
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958 Hypertrophic Lichen Sclerosus: A Form of “Atypical” Lichen Sclerosus in the Pathway to HPV-Independent Squamous Cell Carcinoma of the Vulva (2026)
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Generalized Petechial‐Purpuric Eruption in a Child: A Rare Presentation of Parvovirus B19 Infection (2026)
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Mimicry in the vasculature: a review of diagnostic clues in cutaneous intravascular lymphoid proliferations (2026)
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Non-Neoplastic Disorders of the Skin (2025)
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A network-based cross-sectional study of geographic access disparities to Medicare-participating dermatologists in the United States (2025)
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A Case of Norwegian Scabies in a Kidney Transplant Patient. (2025)PubMed OpenAlex
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Merkel Cell Carcinoma Arising in Combination With Basal Cell Carcinoma: A Rare Diagnosis and Potential Pitfall (2025)
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Violaceous Nodules in an Infant With Noonan Syndrome: Challenge (2025)
Federal Grants 1 $269,148 total
Clinician Research Education and Scientific Training (CREST) Program
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Kinase Suppressor of ras: Function in the hippocampus NIH Principal Investigator
- Identification of Druggable Targets to Complement Melanoma Therapy NIH Co-Investigator
Collaboration Network
Top Collaborators
- Superficial fibrin thrombi … and other findings: a review of the histopathology of human scabietic infections
- Impact of Pathologist Involvement in Sarcoma and Rare Tumor Patient Support Groups on Facebook: A Survey of 542 Patients and Family Members
- Nuclear factor XIIIa staining (clone AC‐1A1 mouse monoclonal) is a highly sensitive marker of sebaceous differentiation in normal and neoplastic sebocytes
- Plaque‐like CD34‐Positive Dermal Fibroma/Medallion‐like Dermal Dendrocyte Hamartoma: An Unusual Spindle Cell Neoplasm
- Interface dermatitis along Blaschko's lines
Showing 5 of 27 shared publications
- Nuclear factor XIIIa staining (clone AC‐1A1 mouse monoclonal) is a highly sensitive marker of sebaceous differentiation in normal and neoplastic sebocytes
- Nuclear factor XIIIa staining (clone AC‐1A1 mouse monoclonal) is a sensitive and specific marker to discriminate sebaceous proliferations from other cutaneous clear cell neoplasms
- Characterization of dermatopathology fellowship applicants: a 5‐year single institution experience
- Epithelioid melanocytic nevus with tubule and pseudoacini formation
- Signet-Ring Cell Melanoma
Showing 5 of 13 shared publications
- Current state of melanoma diagnosis and treatment
- Indicators of responsiveness to immune checkpoint inhibitors
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
- Role of EZH2 histone methyltrasferase in melanoma progression and metastasis
- Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack
Showing 5 of 12 shared publications
- Indicators of responsiveness to immune checkpoint inhibitors
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
- Role of EZH2 histone methyltrasferase in melanoma progression and metastasis
- Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack
- Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma
Showing 5 of 8 shared publications
- Colliding, colonizing or combining? Four cases illustrating the unique challenges presented by melanoma arising in conjunction with basal cell carcinoma
- Hansen Disease (Leprosy) and Armadillo Exposure in Arkansas: A Case Series
- Metastatic laryngeal large cell neuroendocrine carcinoma: A rare case of presentation and extreme tumor burden
- ALK Rearrangements Are Infrequent in Cellular Blue Nevus and Deep Penetrating Nevus
- Prospective Consensus Reporting by Gynecologic Pathology and Dermatopathology Improves Diagnosis of Vulvar Biopsies
Showing 5 of 8 shared publications
- Indicators of responsiveness to immune checkpoint inhibitors
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
- Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma
- Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression
- Proteomic signatures of innate immunity in immunotherapy naïve melanomas correlate with anti-CTLA-4 immunotherapy responsiveness
Showing 5 of 7 shared publications
- A case of proteasome-associated auto-inflammatory syndrome with compound heterozygous mutations
- Granulomatous pigmented purpuric dermatosis
- Loss of Cytokeratin 20 and Acquisition of Thyroid Transcription Factor-1 Expression in a Merkel Cell Carcinoma Metastasis to the Brain
- A novelCYLDgene mutation and multiple basal cell carcinomas in a patient with Brooke-Spiegler syndrome
- A case of cutaneous Rosai-Dorfman disease (CRDD) with underlying calvarial involvement and absence of BRAFV600E mutation
Showing 5 of 6 shared publications
- Indicators of responsiveness to immune checkpoint inhibitors
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
- Role of EZH2 histone methyltrasferase in melanoma progression and metastasis
- Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack
- Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma
Showing 5 of 6 shared publications
- Indicators of responsiveness to immune checkpoint inhibitors
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
- Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma
- Proteomic signatures of innate immunity in immunotherapy naïve melanomas correlate with anti-CTLA-4 immunotherapy responsiveness
- Identification of Misregulated Histone Post Translational Modifications in Melanoma
Showing 5 of 6 shared publications
- Lichenoid dermatoses involving the vulva: A clinical-pathologic correlation✰
- Immunologic overlap in a case of linear IgG/IgA bullous dermatosis responsive to rituximab
- Dermatofibrosarcoma protuberans with platelet‐derived growth factor‐D rearrangement; two cases with morphologically distinct presentations
- Consecutive Immunohistochemical Staining on a Single Slide is Effective in Confirming Melanocytic Derivation
- Vulvar Melanocytic Lesions
Showing 5 of 6 shared publications
- A Pink Pedal Plaque in an 8-Year-Old Boy
- Bilateral eyelid swelling as the presenting sign of subcutaneous sarcoidosis
- Unilateral Pachydermodactyly in a Young Female: A Rare Diagnosis Requiring Novel Clinicopathological Correlation
- Violaceous Nodules in an Infant With Noonan Syndrome: Answer
- Violaceous Nodules in an Infant With Noonan Syndrome: Challenge
Showing 5 of 6 shared publications
- Superficial fibrin thrombi … and other findings: a review of the histopathology of human scabietic infections
- Nuclear factor XIIIa staining (clone AC‐1A1 mouse monoclonal) is a highly sensitive marker of sebaceous differentiation in normal and neoplastic sebocytes
- Desmoplastic melanoma presenting as primary alopecia neoplastica: a report of two cases
- A case of a giant sarcomatoid basal cell carcinoma with heterologous osteosarcomatous elements
- Characterization of dermatopathology fellowship applicants: a 5‐year single institution experience
- Indicators of responsiveness to immune checkpoint inhibitors
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
- Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression
- Proteomic signatures of innate immunity in immunotherapy naïve melanomas correlate with anti-CTLA-4 immunotherapy responsiveness
- Abstract LB-206: Indicators of responsiveness to immune checkpoint inhibitors
- Nuclear factor XIIIa staining (clone AC‐1A1 mouse monoclonal) is a highly sensitive marker of sebaceous differentiation in normal and neoplastic sebocytes
- Nuclear factor XIIIa staining (clone AC‐1A1 mouse monoclonal) is a sensitive and specific marker to discriminate sebaceous proliferations from other cutaneous clear cell neoplasms
- Characterization of dermatopathology fellowship applicants: a 5‐year single institution experience
- Epithelioid melanocytic nevus with tubule and pseudoacini formation
- A case of proteasome-associated auto-inflammatory syndrome with compound heterozygous mutations
- Benign lymphangioendothelioma presenting as a giant flank mass
- Benign lymphangioendothelioma presenting as a giant flank mass: Giant lymphangioendothelioma
- Nonlymphoid Tumors Mimicking Lymphoma
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