Samuel G. Mackintosh

High Impact

Professor

UAMS primary UA Little Rock

Also affiliated: University of North Carolina at Chapel Hill (2020); University of Rome Tor Vergata (2016); University of California, Los Angeles (2022); University of Arkansas Medical Center (2015–2020); University of Arkansas System (2020–2022); Central Arkansas Veterans Healthcare System (2016); UCLA Jonsson Comprehensive Cancer Center (2022); Arkansas Children's Research Institute (2024)

Biochemistry & Molecular Biology, College of Medicine

37 h-index 153 pubs 4,753 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group UAMS TRI Profile

OverviewAI-generated summary

Samuel G. Mackintosh serves as Professor in Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences. He has extensive experience, spanning nearly two decades, in the operation and maintenance of nanoflow liquid chromatography mass spectrometry (MS) instrument systems, including various Thermo Orbitrap models. As Managing Director of the IDeA National Resource for Quantitative Proteomics and Co-Director of the UAMS WP Rockefeller Cancer Institute Proteomics Shared Resource, Mackintosh collaborates with principal investigators to apply MS technology to diverse research projects.

His work involves planning research, preparing biological samples for MS analysis, operating and maintaining HPLC and MS instruments, and analyzing MS data. He routinely uses software such as Mascot, MaxQuant, Scaffold, and Spectronaut for data analysis. In the past five years, nearly 50 publications from users of the IDeA National Resource for Quantitative Proteomics have incorporated data generated in his facility. Mackintosh has a strong record of collaboration, with numerous shared publications with colleagues at the University of Arkansas for Medical Sciences, including Ricky D. Edmondson, Stephanie D. Byrum, Alan J. Tackett, and Aaron J. Storey. His scholarly output is recognized by an h-index of 37 and over 4,700 citations across 153 publications.

Metrics

h-index: 37
Publications: 153
Citations: 4,753

Positions

Professor 2006–present

University of Arkansas for Medical Sciences Biochemistry & Molecular Biology, College of Medicine Institutional directory

Selected Publications

Human gastric extracellular matrix hydrogels maintain organoid growth and reduce gene expression associated with stemness and inflammation (2026)

Biomedical Materials DOI OpenAlex
Effect of complement 3/5 knockout on renal proteomics landscape after ischemia and reperfusion injury in rats (2026)

Physiological Reports DOI OpenAlex
Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)

Figshare DOI OpenAlex
A method utilizing chemical carcinogens and a Western diet to reliably induce advanced hepatocellular carcinoma in male and female mice (2026)

Cancer & Metabolism DOI OpenAlex
Abstract 6079: Resistance-specific proteogenomics in melanoma PDXs (2026)

Cancer Research DOI OpenAlex
A new chemical carcinogen and Western diet protocol to reliably induce advanced hepatocellular carcinoma in male and female mice (2026)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex

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Grants & Funding

As listed on this researcher's institutional profile.

HCV NS3: Biological, Biochemical and Structural Analysis NIH Co-Investigator
Single molecule nucleic acid enzymology NIH Co-Investigator
Orbitrap Fusion Tribrid Mass Spectrometer NIH Principal Investigator
Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer NIH/Office of the Director Principal Investigator
Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer NIH Principal Investigator
IDeA National Resource for Quantitative Proteomics NIH Co-Investigator