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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-03

Seongok Lee

Post Doctoral Fellow

Also affiliated: Yonsei University (2011); Yonsei University Health System (2011); Catholic University of Korea (2011–2015)

Radiation Oncology, College of Medicine

3 h-index 13 pubs 33 cited

  • Animals
  • Humans
  • Kidney Transplantation
  • DNA Repair
  • Kidney
  • Tumor Suppressor p53-Binding Protein 1
  • Histones
  • Male
  • Rats
  • Organ Preservation
  • Proteasome Endopeptidase Complex
  • BRCA1 Protein
  • DNA Damage
  • Ubiquitin-Protein Ligases
  • Ubiquitination

Biography and Research Information

OverviewAI-generated summary

Seongok Lee's research focuses on understanding the molecular mechanisms underlying DNA repair and cellular responses to damage. Recent work has investigated the role of histone modifications and associated proteins, such as 53BP1 and RNF168, in regulating homologous recombination and DNA double-strand break repair pathways. Lee has also explored the impact of organ preservation and transplantation on kidney injury and the function of the immunoproteasome in rat kidney allografts. Prior research has examined cephalosporin resistance mechanisms in Escherichia coli and the prevalence of imipenem or meropenem resistance in Klebsiella pneumoniae and Escherichia coli.

Metrics

  • h-index: 3
  • Publications: 13
  • Citations: 33

Positions

  • Post Doctoral Fellow publications 2023–2026
    University of Arkansas for Medical Sciences Radiation Oncology, College of Medicine Institutional directory

Selected Publications

  • Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation (2026)
    American Journal of Physiology-Renal Physiology DOI OpenAlex
  • 137 Protocol optimization for adenine nephropathy in Ahr genotype-divergent mouse strains (2026)
    Journal of Clinical and Translational Science DOI OpenAlex
  • Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats (2025)
    Journal of the American Society of Nephrology DOI OpenAlex
  • Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat (2025)
    Physiological Reports 4 citations DOI OpenAlex
  • Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640) (2025)
    Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
  • Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749) (2025)
    Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
  • Mechanism of Impaired Protein Homeostasis in Kidney Grafts following Cold Storage and Transplant (2024)
    Journal of the American Society of Nephrology DOI OpenAlex
  • Evolved histone tail regulates 53BP1 recruitment at damaged chromatin (2024)
    Nature Communications 13 citations DOI OpenAlex
  • Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation (2024)
    International Journal of Molecular Sciences 3 citations DOI OpenAlex
  • Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function (2024)
    Kidney360 4 citations DOI OpenAlex
  • Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model (2023)
    Journal of the American Society of Nephrology 1 citation DOI OpenAlex
  • Cold Storage-Mediated p38MAPK Activation: A Potential Contributor of Proteasome Dysfunction and Kidney Damage After Transplantation (2023)
    Journal of the American Society of Nephrology DOI OpenAlex
  • Mechanism of Cold Storage-Mediated Regulation of Heat Shock Proteins in Renal Grafts After Transplantation (2023)
    Journal of the American Society of Nephrology DOI OpenAlex
  • UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair (2023)
    Journal of Biological Chemistry 10 citations DOI OpenAlex
  • ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination (2022)
    Nucleic Acids Research 39 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

38 Collaborators 9 Institutions 2 Countries

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