Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
S
Seongok Lee
Post Doctoral Fellow
Also affiliated: Yonsei University (2011); Seonam University (2021–2024); Catholic University of Korea (2011–2015)
Postdoc Researcher
Radiation Oncology, College of Medicine
4 h-index
14 pubs
128 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Seongok Lee's research investigates mechanisms of kidney injury and transplantation, with a focus on the roles of complement and proteasomes. Recent studies have examined the impact of cold storage followed by transplantation on rat kidney allografts, specifically observing the induction of the immunoproteasome and the necessity of normal proteasome function to prevent graft injury. Further work explores the involvement of Complement 5 in mitochondria during kidney ischemia-reperfusion injury in rats, including the effects in a complement 5 knockout rat model. Lee also contributes to research on DNA repair pathways, investigating the roles of proteins such as ZMYM2, 53BP1, and UBA80 in maintaining genomic stability. These studies involve animal models and molecular biology techniques to elucidate complex biological processes relevant to disease and injury.
Metrics
- h-index: 4
- Publications: 14
- Citations: 128
Selected Publications
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Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation (2026)
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137 Protocol optimization for adenine nephropathy in Ahr genotype-divergent mouse strains (2026)
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Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats (2025)
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Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat (2025)
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Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640) (2025)
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Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749) (2025)
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Mechanism of Impaired Protein Homeostasis in Kidney Grafts following Cold Storage and Transplant (2024)
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Evolved histone tail regulates 53BP1 recruitment at damaged chromatin (2024)
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Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation (2024)
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Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function (2024)
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Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model (2023)
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Cold Storage-Mediated p38MAPK Activation: A Potential Contributor of Proteasome Dysfunction and Kidney Damage After Transplantation (2023)
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Mechanism of Cold Storage-Mediated Regulation of Heat Shock Proteins in Renal Grafts After Transplantation (2023)
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UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair (2023)
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ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination (2022)
Collaboration Network
Top Collaborators
Nirmala Parajuli
University of Arkansas for Medical Sciences
10 shared publications
In database
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation
- Mechanism of Cold Storage-Mediated Regulation of Heat Shock Proteins in Renal Grafts After Transplantation
- Cold Storage-Mediated p38MAPK Activation: A Potential Contributor of Proteasome Dysfunction and Kidney Damage After Transplantation
- Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model
Showing 5 of 10 shared publications
Dinesh Bhattarai
University of Arkansas for Medical Sciences
7 shared publications
In database
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation
- Cold Storage-Mediated p38MAPK Activation: A Potential Contributor of Proteasome Dysfunction and Kidney Damage After Transplantation
- Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model
- Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749)
Showing 5 of 7 shared publications
Madison McGraw
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model
- Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749)
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats
Justin Leung
The University of Texas Health Science Center at San Antonio (US)
3 shared publications
- ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
Jessica L Kelliher
University of Arkansas for Medical Sciences
2 shared publications
In database
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
Wan Song
The University of Texas Health Science Center at San Antonio (US)
2 shared publications
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
Eloïse Dray
The University of Texas Health Science Center at San Antonio (US)
2 shared publications
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
Neelam Joshi
University of Arkansas for Medical Sciences
2 shared publications
In database
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
Se‐Ran Jun
University of Arkansas for Medical Sciences
2 shared publications
In database
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640)
Gopinath Venugopal
University of Arkansas for Medical Sciences
2 shared publications
In database
- Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640)
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
Amod Sharma
University of Arkansas for Medical Sciences
2 shared publications
In database
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats
Neriman Gokden
University of Arkansas for Medical Sciences
2 shared publications
In database
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats
Doo‐Hyung Lee
The University of Texas at Austin (US)
1 shared publication
- ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
Katja Apelt
Leiden University Medical Center (NL)
1 shared publication
- ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
Hsin‐Ru Chan
The University of Texas at Austin (US)
1 shared publication
- ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
Similar Researchers
Based on overlapping research topics
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