Dinesh Bhattarai

Sourced from institutional research profiles (UAMS TRI or ARA).

Post Doctoral Fellow

UAMS

Also affiliated: Louisiana State University (2020–2025); United Nations (2019–2023); Louisiana State University Agricultural Center (2024); Tribhuvan University (2017); Huazhong Agricultural University (2015–2020); University of Utah (2026); Government of Nepal (2022); Agriculture and Forestry University (2018–2019); Jianghan University (2017); Hubei Water Resources Research Institute (2017); University of Applied Management Studies (2025); Kathmandu University (2022)

Postdoc Researcher

14 h-index 51 pubs 883 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website UAMS TRI Profile

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OverviewAI-generated summary

Dinesh Bhattarai's research investigates mechanisms of kidney injury and transplantation, with a focus on the role of the immunoproteasome and cold storage.

His work has explored how cold storage impacts the proteome and phosphoproteome landscape of rat kidney allografts. He has also examined the influence of hypothermic machine perfusion on oxidative stress markers and early tubular injury in donor kidneys prior to transplantation. Further research has investigated the complement system's role in kidney ischemia-reperfusion injury in rats.

Bhattarai also studies host defense mechanisms against sepsis, specifically the negative regulation of host defense by NLRP6 in polymicrobial sepsis. His publications include work on apoptosis, kidney transplantation, and sepsis in animal models. He has an h-index of 14 and 864 citations across 50 publications. Collaborations include Nirmala Parajuli, Seongok Lee, Madison McGraw, and Lee Ann MacMillan-Crow, all at the University of Arkansas for Medical Sciences.

Metrics

h-index: 14
Publications: 51
Citations: 883

Selected Publications

Effect of complement 3/5 knockout on renal proteomics landscape after ischemia and reperfusion injury in rats (2026)

Physiological Reports DOI OpenAlex
Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation (2026)

American Journal of Physiology-Renal Physiology DOI OpenAlex
Novel interactions between the <scp>C5</scp> ‐ <scp>C5aR</scp> 1 Axis and <scp>IF</scp> 1: Implications for kidney mitochondrial physiology and ischemia–reperfusion injury (2026)

Physiological Reports 2 citations DOI OpenAlex
Cold Storage Induced Mortalin-Mediated SDHA Proteostasis to Drive Mitochondrial Dysfunction in Kidney Transplants (Abstract ID: 225742) (2026)

Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
Influence of Hypothermic Machine Perfusion on Markers of Oxidative Stress and Early Tubular Injury in Rat Donor Kidneys Before Transplantation (2026)

Kidney and Dialysis DOI OpenAlex
Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats (2025)

Journal of the American Society of Nephrology DOI OpenAlex
Compared with Static Cold Storage, Hypothermic Machine Perfusion Mitigates Oxidative Stress and Tubular Injury in Rat Kidneys (2025)

Journal of the American Society of Nephrology DOI OpenAlex
Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat (2025)

Physiological Reports 4 citations DOI OpenAlex
Cold Storage-Induced Proteasome Dysfunction in Rat Kidney Transplants: A Plausible Role of p38MAPK Signaling (Abstract ID: 161861) (2025)

Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749) (2025)

Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
Cold Storage Disrupts the Proteome and Phosphoproteome Landscape in Rat Kidney Transplants (2024)

Transplantation 3 citations DOI OpenAlex
Cold Storage-Mediated Activation of P38MAPK-MK2 Axis Induces Kidney Injury after Transplantation (2024)

Journal of the American Society of Nephrology DOI OpenAlex
Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation (2024)

International Journal of Molecular Sciences 3 citations DOI OpenAlex
Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function (2024)

Kidney360 4 citations DOI OpenAlex
Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model (2023)

Journal of the American Society of Nephrology 1 citation DOI OpenAlex