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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-09

Shabiha Afroj Heeamoni

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Also affiliated: University of Dhaka (2024–2025)

1 h-index 6 pubs 7 cited

  • Enhancer of Zeste Homolog 2 Protein
  • RNA Splicing
  • Oligonucleotides, Antisense
  • Gene Regulatory Networks
  • Serine-Arginine Splicing Factors
  • Animals
  • Humans
  • Mutation
  • Gene Expression Regulation, Neoplastic
  • Cell Line, Tumor
  • Mice
  • Nonsense Mediated mRNA Decay

Biography and Research Information

OverviewAI-generated summary

Shabiha Afroj Heeamoni's research focuses on understanding gene regulation and its implications in cancer, particularly bladder cancer. Her work investigates the roles of splicing factors, such as SRSF6 and SRSF1, in generating specific protein isoforms, like a Wnt-sensitive MuSK isoform. She also studies the oncogenic splicing activity of Enhancer of Zeste Homolog 2 (EZH2) and explores potential therapeutic strategies, including antisense oligonucleotide correction. Heeamoni's research extends to the impact of TP53 gene mutations on gene expression and patient survival in bladder cancer. She has also identified prognostic signatures associated with the epithelial-mesenchymal transition pathway in bladder cancer using TCGA database analysis. Her recent publications include work on targeting EZH2 oncogenic splicing, CRISPR-mediated correction of oncogenic AS-NMD, and the prognostic significance of the TP53 gene in bladder cancer.

Metrics

  • h-index: 1
  • Publications: 6
  • Citations: 7

Selected Publications

  • Targeting EZH2 oncogenic splicing: decoding the regulatory network and antisense correction (2026)
    Genes & Development DOI OpenAlex
  • CRISPR-mediated Correction of Oncogenic AS-NMD in Splicing Factor Mutant Cancer (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Targeting EZH2 Oncogenic Splicing: Decoding the Regulatory Network and Antisense Correction (2026)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform (2025)
    NAR Molecular Medicine 5 citations DOI OpenAlex

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Collaboration Network

22 Collaborators 9 Institutions 2 Countries

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