Biography and Research Information
OverviewAI-generated summary
Farhana Nasrin's research investigates the molecular mechanisms underlying gene regulation, with a particular focus on alternative splicing and its role in disease. Her work has explored how proteins like hnRNP H and CstF64 influence the production of different acetylcholinesterase isoforms. She has also studied the antagonistic regulation of COLQ exon 16 splicing by SRSF1 and hnRNP H in congenital myasthenic syndrome, and how hnRNP C, YB-1, and hnRNP L affect MUSK exon 10 skipping to generate a Wnt-insensitive MuSK isoform. Nasrin's publications also address the splicing regulation of cholinergic genes at the neuromuscular junction and GFPT1 isoforms related to glucose metabolism and neuromuscular junction function. Additionally, her research has touched on the detection of Mycobacterium tuberculosis and the structural properties of DNA in immune adaptor genes.
Metrics
- h-index: 7
- Publications: 21
- Citations: 238
Positions
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Staff Scientist 2021–presentUniversity of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
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Postdoctoral Fellow 2017–2021Cold Spring Harbor Laboratory ORCID
Selected Publications
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G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025)
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SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform (2025)
Collaboration Network
Top Collaborators
- SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform
- SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform
- SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform
- SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform
- SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform
- SRSF6 and SRSF1 coordinately enhance the inclusion of human MUSK exon 10 to generate a Wnt-sensitive MuSK isoform
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
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