Vikrant Vijay

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Staff Fellow (Pharmacologist)

NCTR

Also affiliated: United States Food and Drug Administration (2013–2026); Center for Drug Evaluation and Research (2020); North Carolina State University (2007–2009); Annamalai University (2011); Yashoda Hospital (2023); Advanced Energy Materials (United States) (2015); Youth Development (2025); Joint Research Center (2015); RMIT University (2015)

Staff Researcher

16 h-index 45 pubs 1,203 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Vikrant Vijay's research focuses on understanding and predicting drug-induced toxicities, particularly cardiotoxicity. His work investigates the molecular mechanisms underlying these adverse effects, employing techniques such as gene expression profiling and metabolomics. A significant portion of his research has examined the cardiotoxic effects of doxorubicin, an antineoplastic antibiotic, in mouse models. He has explored delayed-onset cardiotoxicity and the potential role of specific pathways, like the apelin-APJ pathway, in sex-related differential toxicity. Vijay has also identified circulating microRNAs as potential early biomarkers for chronic cardiotoxicity. His research extends to the development of frameworks for integrating transcriptomics and metabolomics data in regulatory toxicology and has explored metabolomics for identifying biomarkers in COVID-19 patient plasma. Collaborations include work with researchers from the National Center for Toxicological Research and the University of Arkansas for Medical Sciences.

Metrics

h-index: 16
Publications: 45
Citations: 1,203

Selected Publications

Correction: Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2026)

Cardiovascular Toxicology DOI OpenAlex
Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2025)

Cardiovascular Toxicology DOI OpenAlex
Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers (2024)

Metabolomics 4 citations DOI OpenAlex
Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin (2024)

Toxicological Sciences 4 citations DOI OpenAlex
Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice (2022)

Journal of Applied Toxicology 7 citations DOI OpenAlex
MicroRNA‐34a‐5p as a promising early circulating preclinical biomarker of doxorubicin‐induced chronic cardiotoxicity (2022)

Journal of Applied Toxicology 14 citations DOI OpenAlex
Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice (2021)

Journal of Applied Toxicology 15 citations DOI OpenAlex
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology (2021)

Regulatory Toxicology and Pharmacology 95 citations DOI OpenAlex
Gene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with estradiol benzoate, estradiol, and testosterone (2020)

The Journal of Toxicological Sciences 2 citations DOI OpenAlex
Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism (2020)

Drug Metabolism and Disposition 21 citations DOI OpenAlex
Rebuttal to the comments by Dr. Yan Xu on the article “Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone” (2019)

Reproductive Toxicology DOI OpenAlex
Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice (2018)

Toxicology and Applied Pharmacology 23 citations DOI OpenAlex
Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone (2018)

Reproductive Toxicology 10 citations DOI OpenAlex
In Vitro Modulation of Redox and Metabolism Interplay at the Brain Vascular Endothelium: Genomic and Proteomic Profiles of Sulforaphane Activity (2018)

Scientific Reports 21 citations DOI OpenAlex
Sex and age differences in the expression of liver microRNAs during the life span of F344 rats (2017)

Biology of Sex Differences 33 citations DOI OpenAlex