Vikrant Vijay
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Staff Fellow (Pharmacologist)
Also affiliated: United States Food and Drug Administration (2011–2026); Center for Drug Evaluation and Research (2020); North Carolina State University (2007–2009)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Vikrant Vijay's research focuses on the pharmacological effects and toxicity of drugs, particularly in the context of cardiotoxicity and liver injury. He has investigated early biomarkers of doxorubicin-induced heart injury in mouse models, examining gene expression profiles and metabolomic changes in the heart and plasma during chronic doxorubicin treatment. His work also explores sex and age differences in gene expression within the kidney and heart of F344 rats, specifically looking at mitochondria-related genes and microRNA expression. Vijay has also contributed to discussions on regulatory toxicology frameworks, including progress towards an OECD reporting framework for transcriptomics and metabolomics. His collaborators include researchers from the National Center for Toxicological Research and the University of Arkansas for Medical Sciences.
Metrics
- h-index: 16
- Publications: 39
- Citations: 1,203
Positions
-
Staff Fellow (Pharmacologist) 2009–presentNational Center for Toxicological Research Systems Biology ORCID
Selected Publications
-
Correction: Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2026)
-
Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2025)
-
Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers (2024)
-
Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin (2024)
-
Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice (2022)
-
MicroRNA‐34a‐5p as a promising early circulating preclinical biomarker of doxorubicin‐induced chronic cardiotoxicity (2022)
-
Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice (2021)
-
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology (2021)
-
Gene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with estradiol benzoate, estradiol, and testosterone (2020)
-
Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism (2020)
-
Rebuttal to the comments by Dr. Yan Xu on the article “Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone” (2019)
-
Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice (2018)
-
Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone (2018)
-
In Vitro Modulation of Redox and Metabolism Interplay at the Brain Vascular Endothelium: Genomic and Proteomic Profiles of Sulforaphane Activity (2018)
-
Sex and age differences in the expression of liver microRNAs during the life span of F344 rats (2017)
Collaboration Network
Top Collaborators
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
- Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages
- Sex differences in kidney gene expression during the life cycle of F344 rats
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
Showing 5 of 20 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
- Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages
- Sex differences in kidney gene expression during the life cycle of F344 rats
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
Showing 5 of 19 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
- Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages
- Sex differences in kidney gene expression during the life cycle of F344 rats
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
Showing 5 of 14 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
- Sex and age differences in the expression of liver microRNAs during the life span of F344 rats
- Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice
- Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism
Showing 5 of 9 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
- Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice
- Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice
Showing 5 of 7 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
- Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages
- Sex differences in kidney gene expression during the life cycle of F344 rats
- Sex and age differences in the expression of liver microRNAs during the life span of F344 rats
Showing 5 of 6 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
- Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice
- MicroRNA‐34a‐5p as a promising early circulating preclinical biomarker of doxorubicin‐induced chronic cardiotoxicity
- Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice
- MicroRNA‐34a‐5p as a promising early circulating preclinical biomarker of doxorubicin‐induced chronic cardiotoxicity
- Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice
- Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study
- Correction: Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
- Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice
- Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology
- Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice
- Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism
- Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice
- Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
- Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers
- Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice
- Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study
- Correction: Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study
- Reproductive hormone levels and differential mitochondria-related oxidative gene expression as potential mechanisms for gender differences in cardiosensitivity to Doxorubicin in tumor-bearing spontaneously hypertensive rats
- Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice
- Abstract 2554: Doxorubicin induced gender differences in tumor-bearing spontaneously hypertensive rats, with an emphasis on cardiotoxicity
Similar Researchers
Based on overlapping research topics