Valentina K. Todorova

Assistant Professor

UAMS

Last publication 2024 Last refreshed 2026-05-16

faculty

Internal Med, College of Medicine

18 h-index 39 pubs 794 cited

Research Areas

Links

Research Group UAMS TRI Profile

OverviewAI-generated summary

Valentina K. Todorova's research program investigates mechanisms of chemotherapy-induced cardiotoxicity, particularly in the context of breast cancer treatment. Her work has explored the role of neutrophils and the endothelium in subclinical doxorubicin-induced cardiotoxicity. Todorova has also examined circulating exosomal microRNAs and protein profiles as potential predictive biomarkers for treatment response in breast cancer and hepatocellular carcinoma.

Her recent publications include studies on RNA sequencing of heart tissue to understand transcriptomic changes associated with chemotherapy-induced cardiotoxicity and metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients. She has also reviewed research on the effect of neutrophil-to-lymphocyte ratio and vitamin D3 levels on treatment response in breast cancer. Todorova's scholarship metrics include an h-index of 18 with 39 publications and 783 citations. She has collaborated with researchers including Jeanne Y. Wei, Nathan S. Reyna, Dr. Stephanie Byrum, and Allen Gies.

Metrics

h-index: 18
Publications: 39
Citations: 794

Selected Publications

Neutrophil Biomarkers Can Predict Cardiotoxicity of Anthracyclines in Breast Cancer (2024)

6 citations DOI OpenAlex
RNA sequencing of formalin fixed paraffin-embedded heart tissue provides transcriptomic information about chemotherapy-induced cardiotoxicity (2024)

1 citation DOI OpenAlex
Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients (2024)

DOI OpenAlex
Review of: "Effect of neutrophil-to-lymphocyte ratio and vitamin D3 levels on the pathological complete response after neoadjuvant treatment in TNBC and HER2-positive early breast cancer – results of a prospective study" (2023)

DOI OpenAlex
Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells (2023)

10 citations DOI OpenAlex
Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer (2022)

39 citations DOI OpenAlex

View all publications on OpenAlex →

Grants & Funding

Center for Studies of Host Response to Cancer Therapy NIH Co-Investigator
No FP attached UAMS Executive Breast Committee Principal Investigator
Advancing Breast Cancer Treatment through Suppression of Chemo-Resistance UAMS Executive Breast Committee Principal Investigator
Arkansas Claude Pepper Older Americans Independence Center at UAMS NIH Co-Investigator
TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine NIH Co-Investigator
Advancing Breast Cancer Treatment through Suppression of Chemo-Resistance UAMS Executive Breast Committee Principal Investigator
Dietary glutamine and protection against doxorubicin and cyclophosphamide toxicity Susan G. Komen for the Cure Principal Investigator
No FP attached UAMS Executive Breast Committee Principal Investigator